Adrenal

P1

Hematoma: unusual presentation of adrenal masses

Alexandra Vieira1 , Carla Baptista1, Isabel Paiva1, Luisa Barros1, Jacinta Santos1, Mariana Martinho2, Francisco Carrilho1, Manuela Carvalheiro11University Hospital of Coimbra, EPE, Portugal, 2Portuguese, Institute of Oncology, FG, EPE, Portugal

Adrenal

P2

Von-Hippel Lindau disease and pheochromocytoma- case report

Daniel Silva Vaz1 , J. Queiroz1, E. Lima1, Jorge Dores11Centro hospitalar do Porto, Portugal

Adrenal

P3

Effect of dietary protein on post-prandial salivary cortisol and androgen levels in healthy women volunteers

Alison Lyles1, Emad Al-Dujaili11Queen Margaret University, United Kingdom

Adrenal

P4

Correlation between development of Testicular Adrenal Rest Tumors and Genotype in Children, Adolescents and Adult Males with Congenital Adrenal Hyperplasia.

Annette Mouritsen1 , Niels Jørgensen1, Katharina M. Main1, Marianne Schwartz2, Anders Juul11University Department of Growth and Reproduction, Denmark, 2Department of Clinical Genetics, Denmark

Adrenal

P6

Unbiased stereological study of silymarin effects on adrenocortical structure of dexamethasone treated hamsters

Gholamreza Hamidian1 , Naeem Alboghobeish1, Hossein Najafzadeh Varzi2, Saleh Esmaeilzadeh31Department of Histology, Faculty of Veterinary Medicine, Shahid Chamran Univerity, Iran, Islamic Republic of, 2Department of Pharmacology, Faculty of Veterinary Medicine, Shahid Chamran Univerity, Iran, Islamic Republic of, 3Department of Pathology, Faculty of Veterinary Medicine, Shahid Chamran Univerity, Iran, Islamic Republic of

Adrenal

P7

Use of diurnal rhythm in salivary aldosterone to discriminate between bilateral adrenal hyperplasia (BAH) and aldosterone producing adenoma (APA)

Jenny Manolopoulou1 , Sabine Gerum1, Paolo Mulatero2, Ariadni Spyroglou1, Martin Reincke1, Martin Bidlingmaier11Department of Medicine, University Hospital Innenstadt, Ludwig Maximilians University, Germany, 2Department of Medicine and Experimental Oncology, Division of Medicine and Hypertension, San Giovanni Battista Hospital, Italy

Adrenal

P8

EFFECT OF UNIVERSAL SOMATOSTATIN ANALOG (SOM230) ON PRIMARY ADRENAL CELL CULTURES.

Barbara Mariniello1 , Isabella Finco1, Beatrice Rubin1, Anna Patalano1, Sergio Ferasin1, Maurizio Iacobone1, Ambrogio Fassina1, Franco Mantero11University of Padua, Italy

Adrenal

P9

Replicating the normal cortisol circadian rhythm using a formulation of modified-release hydrocortisone

Miguel Debono1 , Cyrus Ghobadi6, Amin Rostami-Hodjegan6, Hiep Huatan2, Mike Campbell7, John Newell-Price1, Ken Darzy3, Deborah P Merke4, Wiebke Arlt5, Richard Ross11Academic Unit of Diabetes, Endocrinology & Metabolism, University of Sheffield, United Kingdom, 2H2 Pharma, United Kingdom, 3East and North Hertfordshire NHS Trust, United Kingdom, 4National Institutes of Health Clinical Center and The Eunice Kennedy Shriver National Institute of Child Health and Human Development, United States, 5Section Endocrinology, Diabetes & Metabolism, School of Clinical & Experimental Medicine, University of Birmingham, United Kingdom, 6Academic Unit of Clinical Pharmacology, University of Sheffield, United Kingdom, 7Health Services Research ScHARR, University of Sheffield, United Kingdom

Adrenal

P10

The cortisone to cortisol conversion in autoimmune Type 1 diabetes

Katerina Simunkova1 , Lubomir Kriz1, Martin Hill1, Jana Vrbíková1, Richard Hampl1, Vaclav Zamrazil1,2, Denisa Janickova1,2, Karel Vondra11Institute of Endocrinology, Czech Republic, 2University hospital Motol, Czech Republic

Adrenal

P11

ARE THERE SOME ALTERATIONS OF SALIVARY CORTISOL DYNAMICS IN OBESE PATIENTS?

Svetlana Jelic1 , Zorica Caparevic1, Sanja Ilic1, Djordje Marina11Dr Dragisa Misovic-Dedenje, Clinical-Hosopital Center, Serbia

Adrenal

P12

Short term regulation of aldosterone secretion after stimulation and suppression experiments in mice

Ariadni Spyroglou1 , Jenny Manolopoulou1, Martin Reincke1, Martin Bidlingmaier1, Felix Beuschlein11Medizinische Klinik Innenstadt, Ludwig Maximilians University, Germany

Adrenal

P13

Autoimmune adrenal insufficiency: Addison's disease vs idiopathic isolated secondary adrenal insufficiency

Anna Kasperlik-Zaluska , Barbara Czarnocka2, Wojciech Jeske3, Lucyna Papierska4, Anna-Lena Hulting5, Sophie Bensing6, Patricia Crock7, Olle Kämpe81gy, Centre for Postgraduate Medical Education, Poland, 2Department of Biochemistry and Molecular Medicine, Centre for Postgraduate Medical Education, Poland, 3Department of Endocrinology, Centre for Postgraduate Medical Education, Poland, 4Department of Endocrinology, Centre for Postgraduate Medical Education, Poland, 5Department of Molecular Medicine, Karolinska Institutet, Karolinska Hospital, Sweden, 6Department of Molecular Medicine, Karolinska Institutet, Karolinska Hospital, Sweden, 7John Hunter Children's Hospital, University of Newcastle, Australia, 8Department of Medical Sciences, University Hospital, Sweden

Adrenal

P14

Prediction of metabolic syndrome by low serum testosterone levels in men: Results from the Study of Health in Pomerania

Robin Haring1 , Henry Völzke1, Stephan B. Felix1, Sabine Schipf1, Marcus Dörr1, Dieter Rosskopf1, Matthias Nauck1, Christof Schöfl2, Henri Wallaschofski11Ernst Moritz Arndt University, Germany, 2Friedrich-Alexander-University, Germany

Adrenal

P15

Prediction of Fatal Stroke by High Serum Aldosterone Levels

Andreas Tomaschitz1 , Stefan Pilz1, Harald Dobnig1, Bernhard R. Winkelmann2, Wilfried Renner3, Bernhard O. Boehm4, Winfried Maerz3,51Division of Endocrinology and Nuclear Medicine, Department of Internal Medicine, Medical University of Graz, Austria, 2Cardiology Group, Frankfurt-Sachsenhausen, Germany, 3Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Austria, 4Division of Endocrinology and Diabetes, Department of Internal Medicine, University of Ulm, Germany, 5Synlab Center of Laboratory Diagnostics Heidelberg, Germany

Adrenal

P16

Effects of castration and testosterone treatment on adrenal activity of a saharan gerbil, Meriones libycus In breeding and non breeding season

Nawel AKNOUN1 , Yamina ZATRA1, Farida KHAMMAR1, Zaina AMIRAT11USTHB Science and Technology University, Algeria

Adrenal

P17

Gitelman syndrome: clinical presentation and genetic analysis of 27 patients with hypokalemia caused by renal potassium wasting

Anne-Sophie Balavoine1 , Pierre Bataille2, Philippe Vanhille3, Raymond Azar4, François Glowacki1, Rosa Vargas-Poussou5, Xavier Jeunemaitre5, Jean-Louis Wémeau1, Marie-Christine Vantyghem11CHRU, France, 2Centre hospitalier, France, 3Centre hospitalier, France, 4Centre hospitalier, France, 5HEGP, France

Adrenal

P18

Bilateral adrenal incidentalomas - a clinical study of 1710 patients observed at a single endocrinological centre

Anna Kasperllik-Zaluska , Jadwiga Slowinska-Srzednicka1, Elzbieta Roslonowska1, Magdalena Kochman1, Wojciech Zgliczynski1, Wojciech Jeske1, Maciej Otto7, Andrzej Cichocki81Department of Endocrinology, Centre for Postgraduate Medical Education, Poland, 2Department of Endocrinology, Centre for Postgraduate Medical Education, Poland, 3Department of Endocrinology, Centre for Postgraduate Medical Education, Poland, 4Department of Endocrinology, Centre for Postgraduate Medical Education, Poland, 5Department of Endocrinology, Centre for Postgraduate Medical Education, Poland, 6Department of Endocrinology, Centre for Postgraduate Medical Education, Poland, 7Department of General, Vascular and Transplant Surgery, Medical University of Warsaw, Poland, 8Department of Surgery, Maria Sklodowska-Curie Memorial Cancer Center and Institutee of Oncology, Poland

Adrenal

P19

Adipokine levels in patients with adrenal incidentaloma.

Laura Iorio1, Valentina Morelli2, Francesca Coletti3, Sonia Della Casa4, Maura Arosio3, Massimiliano Corsi5, Iacopo Chiodini2, Bruno Ambrosi11Endocrinology Unit, Department of Medical and Surgical Sciences, IRCCS Policlinico San Donato, University of Milan, Italy, 2Endocrinology Unit, Department of Medical and Surgical Sciences, IRCCS Fondazione Ospedale Maggiore Policlinico, Mangiagalli, Regina Elena, University of Milan, Italy, 3Endocrinology Unit, San Giuseppe-MilanoCuore Hospital, AfaR, Italy, 4Chair of Endocrinology, Catholic University, Italy, 5Laboratory of Clinical Pathology, Institute of General Phatology, Italy

Adrenal

P20

Chemokine receptor expression in the adrenal cortex and in adrenocortical tumours

Katharina Lang1 , Andrea Stürmer1, Patrick Adam2, Martin Fassnacht1, Marcus Quinkler3, Michael Morcos4, Bruno Allolio1, Stefanie Hahner11Department of Internal Medicine I, Dept. of Endocrinology, Germany, 2Department of Pathology, University of Wuerzburg, Germany, 3Dept of Medicine, Gastroenterology, Hepatology and Endocrinology, Charité Campus Mitte, Charité University Medicine Berlin, Germany, 4Department of Internal Medicine 1, Endocrinology, Metabolism and Clinical Chemistry, Germany

Adrenal

P21

Bilateral Macronodular Adrenal Hyperplasia VERSUS Bilateral Micronodular Adrenal Hyperplasia

Nur Kebapci1 , Belgin Efe1, Mahmut Kebapci21Eskisehir Osmangazi University, Department of Endocrinology, Turkey, 2Eskisehir Osmangazi University, Department of Radiology, Turkey

Adrenal

P22

ROLE OF CHEMOKINES MIP1α AND MIP1β IN PATIENTS WITH ADDISON’S DISEASE ISOLATED OR ASSOCIATED TO AUTOIMMUNE THYROID DISEASE.

Annamaria De Bellis1, Elena Pane1, Marina Battaglia1, Giuseppe Ruocco1, Gilda Tirelli1, Giuseppe Bellastella1, Antonio Agostino Sinisi1, Costantini Susan2, Francesca Capone2, Annarita Aiello Talamanca2, Rosa Calemma3, Antonio Bizzarro1, Antonio Bellastella11Chair of Endocrinology and Chair of Immunology and Allergology- Department of Clinical and Experimental Medicine and Surgery “F. Magrassi, A. Lanzara”, Second University of Naples, Italy, 2Research Oncological Centre of Mercogliano*, Italy, 3UOSC of Immunology, IRCCS National Tumoral Institute of Naples**, Italy

Adrenal

P23

IL-6 and Osteoprotogerin levels in subjects with non-functioning adrenal adenomas

Serkan Yener1 , Abdurrahman Comlekci1, Faize Yuksel1, Abdurrahman Comlekci1, Baris Akinci1, Tevfik Demir1, Sena Yesil11Dokuz Eylul University, Division of Endocrinology, Turkey, 2Dokuz Eylul University, Division of Hematology, Turkey, 3Dokuz Eylul University, Department of Radiology, Turkey

Adrenal

P24

Characterization of tyrosine hydroxylase (TH) expression in various adrenal tumors to confirm the diagnosis of adrenal pheochromocytomas

Bianca Ueberberg1 , Jakob Hinrichs2, Martin, K. Walz2, Kurt, W. Schmid3, Klaus Mann1, Stephan Petersenn11Division of Endocrinology, Medical Center, University of Duisburg-Essen, Germany, 2Department of Surgery and Center of Minimally Invasive Surgery, Kliniken Essen-Mitte, Germany, 3Institute of Pathology, University of Duisburg-Essen, Germany

Adrenal

P25

Towards an aldosterone producing cell line from an aldosterone producing adenoma

Urs Lichtenauer1 , Oliver Zwermann1, Igor Shapiro1, Thomas Mussack1,2, Martin Reincke1, Felix Beuschlein11Endocrine Research Unit, Medizinische Klinik-Innenstadt, Ludwig-Maximilians-University, Germany, 2Department of Visceral Surgery, Chirurgische Klinik- Innenstadt, Ludwig-Maximilians-University, Germany

Adrenal

P26

CARDIAC STRUCTURE AND FUNCTION IN PATIENTS WITH ADRENAL INCIDENTALOMA: AN ECHOCARDIOGRAPHIC STUDY

Monica De Leo1 , Maurizio Galderisi2, Maria Cristina De Martino1, Alessia Cozzolino1, Annamaria Colao1, Rosario Pivonello1, Gaetano Lombardi11Dept of Clinical and Molecular Endocrinology and Oncology, University Federico II, Italy, 2Dept of Clinical and Experimental Medicine, University Federico II, Italy

Adrenal

P27

AUTOANTIBODY SCREENING OF AUTOIMMUNE GASTROINTESTINAL DISORDERS IN PATIENTS WITH AUTOIMMUNE ADDISON DISEASE

Peter Kentos1 , Mikulas Pura1, Peter Vanuga11Department of Endocrinology, National Institute of Endocrinology and Diabetology, Slovakia

Adrenal

P28

Prior dexamethasone suppression test predicts development of adrenal insufficiency after a 14 days’ course of oral prednisone in healthy male volunteers

Stefanie Neidert1 , Philipp Schuetz1, Beat Mueller2, Mirjam Christ-Crain11Department of Endocrinology, Universitiy Hospital Basel, Switzerland, 2Department of Internal Medicine, Kantonsspital Aarau, Switzerland

Adrenal

P29

Glucocorticoid replacement therapy in adrenocortical insufficiency

Anna Rita Carli1, Gemma Frigato1, Marta Bondanelli1, Maria Chiara Zatelli1, Maria Rosaria Ambrosio1, Ettore degli Uberti11Section of Endocrinology-Department of Biomedical Sciences and Advanced Therapy-University of Ferrara, Italy

Adrenal

P30

Study of hormonal activity and insulin resistance in patients harbouring incidentally discovered bilateral adrenal adenomas

Ioannis Androulakis1 , Lambrini Papanastasiou1, Ermioni Tsenilklidi1, Anastasia Prevoli1, Paraskevi Kafritsa1, Theodora Pappa1, Vaios Tsiavos1, George Piaditis11Department of Endocrinology and Diabetes Center , General Hospital of Athens ‘G.Gennimatas’, Greece

Adrenal

P31

Confounding variables for plasma metanephrines and normetanephrines may influence the diagnosis of pheochromocytomas

Timo Deutschbein1 , Andrea Jäger1, Klaus Mann1, Stephan Petersenn11Division of Endocrinology, University of Duisburg-Essen, Germany

Adrenal

P32

Is adrenal adenoma associated with the development of non alcoholic fatty liver disease?

Serkan Yener1 , Senem Ertilav1, Mustafa Secil2, Baris Akinci1, Tevfik Demir1, Firat Bayraktar1, Sena Yesil11Dokuz Eylul University, Division of Endocrinology, Turkey, 2Dokuz Eylul University, Department of Radiology, Turkey

Adrenal

P33

A multi-institutional audit of laparoscopic adrenalectomy in Greece and the UK

Panagiotis Kekis1, Haridimos Markogiannakis1, Nikolaos Michalopoulos1, Emmanuel Lagoudianakis1, Bill Fleming2, Alberto Martínez-Isla3, John Lynn2, Andreas Manouras11Department of Endocrine Surgery, 1st Department of Propaedeutic Surgery, Hippokrateion Hospital, Athens Medical School, University of Athens, Greece, 2Department of Endocrine Surgery, Hammersmith Hospital, Imperial College Healthcare NHS Trust, United Kingdom, 3Department of Upper Gastrointestinal and Laparoscopic Surgery, Ealing Hospital, Ealing Hospital NHS Trust, United Kingdom

Adrenal

P34

The utility of the low dose dexamethasone suppression test in patients diagnosed with an adrenal incidentaloma

Miguel Debono1 , Charlotte Durrington1, Scott Williams1, John Newell-Price11Academic Unit of Diabetes, Endocrinology & Metabolism, University of Sheffield, United Kingdom

Adrenal

P35

SYNACTEN TEST IN PATIENTS WITH ADRENAL INCIDENTALOMA

Miomira Ivovic1 , Milos Stojanovic1, Milina Tancic-Gajic1, Ljiljana Marina1, Svetlana Vujovic1, Milka Drezgic11Institute of Endocrinology, Serbia

Adrenal

P36

CENTRAL GHRELIN MODULATES MORPHOLOGY AND FUNCTION OF ADRENAL CORTEX IN MALE RATS

Verica Milosevic1 , Branka Sosic-Jurjevic1, Darko Stevanovic2, Milica Terzic2, Dejan Nesic2, Vesna Starcevic2, Milka Sekulic11Institute for Biological Research "Sinisa Stankovic", Serbia, 2Institute of Medical Physiology, School of Medicine, University of Belgrade, Serbia

Adrenal

P37

PHEOCHROMOCYTOMA: A RETROSPECTIVE STUDY ON CLINICAL PRESENTATION, MANAGEMENT AND OUTCOMES

Mariana Martinho2 , Isabel Paiva1, Francisco Carrilho1, Ana Fagulha1, Jacinta Santos1, Alexandra Vieira1, Fernando Rodrigues2, Manuela Carvalheiro11Coimbra’s University Hospital, Portugal, 2Portuguese Institute of Oncology of Coimbra, Portugal

Adrenal

P38

EPIDEMIOLOGICAL STUDY OF ADRENAL MASS IN OUR CLINICAL CENTRE

Jovanka Novakovic-Paro1 , Milena Mitrovic1, Milica Medic-Stojanoska1, Ivana Bajkin1, Tijana Icin1, Dusan Tomic1, Bojan Vukovic1, Branka Kovacev -Zavisic11Clinic of endocrinology, diabetes and metabolic diseases, Clinical Centre of Vojvodina, Serbia

Adrenal

P39

ANEMIA IN MALE PATIENTS WITH CUSHING’S SYNDROME BEFORE AND AFTER CURE

Francesca Pecori Giraldi1, Paola Ascoli1, Martina De Martin1, Nicoletta Polli1, Francesco Cavagnini11Chair of Endocrinology, University of Milan, Dept. Endocrinology, Ospedale San Luca, Istituto Auxologico Italiano, Italy

Adrenal

P40

Bilateral adrenal hemangioma cavernosum: NMI and a CT scanning as a complementary methods in newly detected degeneration in one gland

Dragan Tesic1 , Tijana Icin1, Dragana Bogdanovic2, Olivera Nikolic3, Zoran djermanov4, Pavle Budakov51Clinic of Endocrinmology, Diabetes and Metabolic Diseases, Serbia, 2Institute for Radiology, Serbia, 3Institute for Radiology, Serbia, 4Clinic of Abdominal and Endocrine Surgery, Serbia, 5Institute for Pathology, Serbia

Adrenal

P41

Prospective evaluation of metabolic and anthropometric parameters in non- functioning adrenal adenomas

Serkan Yener1 , Senem Ertilav1, Abdurrahman Comlekci1, Mustafa Secil2, Baris Akinci1, Tevfik Demir1, Sena Yesil11Dokuz Eylul University Division of Endocrinology, Turkey, 2Dokuz Eylul University Department of Radiology, Turkey

Adrenal

P42

Metastases of renal cell carcinoma to the adrenal glands: results of surgical treatment

Vladimir Koloskov1 , Timur Britvin1, Galina Polyakova1, Mikhail Beloshitsky1, Arian Kalinin11Moscow Regional M.F. Vladimirsky Clinical Research Institute, Russian Federation

Adrenal

P43

Iatrogenic Cushing’s syndrome induced by topical corticoid application in child and adult

Dumitru Branisteanu1 , Serban Turliuc1, Blenda Veliaj1, Simona Mogos1, Eusebie Zbranca1, Ionut Repede1, Adrian Aancute1, Voichita Mogos11University of Medicine and Pharmacy "Gr.T.Popa", Romania

Adrenal

P44

A rare cause of hyponatraemia presenting as acute adrenal insufficiency: bilateral adrenal haemorrhage.

Saket Gupta1 , Sarah Hyde1, Babar Abbasi1, Sam Thomas1,2, Shu Hoashi1,21Midlands Regional Hospital in Mullingar, Ireland, 2Royal College of Surgeons in Ireland, Ireland

Adrenal

P45

Long-term follow-up of a 46XX patient with Congenital Lipoid Adrenal Hyperplasia (CLAH) due to a new mutation of the Steroidogenic Acute Regulatory Protein (StAR) gene.

Frédérique Albarel1 , Gilbert Simonin2, Yves Morel3, Thierry Brue1, Rachel Reynaud21Department of Endocrinology, Hôpital Timone and Université de la Méditerranée, France, 2Department of Pediatrics, Hôpital Timone and Université de la Méditerranée, France, 3Laboratory of Biochemistry, Hôpital Debrousse and Université Claude Bernard, France

Adrenal

P46

INSULIN HYPOGLYCEMIA TEST IN THE DIAGNOSIS OF SUBCLINICAL CUSHING’S SYNDROME

Feyza Yener Ozturk1 , Erdinc Erturk1, Metin Guclu1, Sinem Kiyici1, Oguzkaan Unal1, Sazi Imamoglu11Uludag University, Turkey

Adrenal

P47

Carotid intima media thickness is increased and associated with morning cortisol in subjects with non-functioning adrenal incidentaloma

Serkan Yener1 , Sinan Genc2, Baris Akinci1, Mustafa Secil2, Tevfik Demir1, Abdurrahman Comlekci1, Senem Ertilav1, Sena Yesil11Dokuz Eylul University, Division of Endocrinology, Turkey, 2Dokuz Eylul University,Department of Radiology, Turkey

Adrenal

P48

Evidence of increased cardiovascular risk in patients with non secreting unilateral adrenocortical adenomas

Ioannis Androulakis1 , George Kollias2, Athina Markou1, Lambrini Papanastasiou1, Tilemachos Angnostou1, Christos Papamichael2, George Piaditis1, Gregory Kaltsas31Department of Endocrinology and Diabetes Center, General Hospital of Athens “G. Gennimatas”,, Greece, 2Vascular Laboratory, Department of Clinical Therapeutics, Alexandra University Hospital, Greece, 3Endocrine Unit, Department of Pathophysiology, University of Athens, Greece

Adrenal

P49

Laparoscopic resection of a large adrenal oncocytoma.

Nikolaos Michalopoulos1 , Panagiotis Kekis1,2, Maria Liparaki2, Emmanuel Evagelidakis2, Maria Natoudi1, Eleftheria Kleidi1, Haridimos Markogiannakis1, Andreas Manouras11Department of Endocrine Surgery, First Department of Propaedeutic Surgery, Hippokrateion Hospital, Athens Medical School, University of Athens, Greece, 2Athens Medical Center, Greece

Adrenal

P50

Effects of corticosterone intake as stress-alternative hormone on broiler chickens: performance and blood parameters

Tohid Vahdatpour11Department of Animal Science, Islamic Azad University-Shabestar branch, Iran, Islamic Republic of

Adrenal

P51

Evaluation of cardiovascular risk factors in patients with incidentally discovered adrenal adenoma during a follow-up longer than five years

Giuseppe Reimondo1 , Silvia Bovio1, Anna Pia1, Barbara Allasino1, Arianna Ardito1, Ilaria Micossi1, Barbara Zaggia1, Angela Termine1, Alberto Angeli1, Massimo Terzolo11Dipartimento di Scienze Cliniche e Biologiche - Università di Torino - Medicina Interna I - ASO San Luigi, Italy

Adrenal

P52

Expression of mTOR pathway in human adrenocortical carcinomas and in vitro effects of mTOR inhibitors in human adrenocortical cell lines

Maria Cristina De Martino 1,2, Peter van Koetsveld1, Diana Sprij-Mooij1, Richard A. Feelders1, Steven W.J. Lamberts1, Wouter W. de Herder1, Annamaria Colao2, Rosario Pivonello2, Leo J Hofland111Department of Internal Medicine, Division of Endocrinology, Erasmus MC, Netherlands, 22Deparment of Endocrinology & Oncology, “Federico II” University, Italy

Adrenal

P53

Prospective evaluation of tumour size and hormone secretion in adrenal incidentalomas

Serkan Yener1 , Senem Ertilav1, Mustafa Secil2, Baris Akinci1, Tevfik Demir1, Abdurrahman Comlekci1, Sena Yesil11Dokuz Eylul University, Division of Endocrinology, Turkey, 2Dokuz Eylul University, Department of Radiology, Turkey

Adrenal

P54

ROSIGLITAZONE INTERFERES WITH HUMAN ADRENOCORTICAL CARCINOMA GROWTH IN A XENOGRAFT MOUSE MODEL

Monica Mangoni1, Stefania Gelmini1, Gabriella Nesi2, Giada Poli1, Giulia Cantini1, Adriana Lombardi1, Claudio Orlando1, Mario Serio1, Massimo Mannelli1, Michaela Luconi11Dept. Clinical Physiopathology, University of Florence, Italy, 2Dept. Human Pathology and Oncology, University of Florence, Italy

Thyroid

P55

Report of Twelve Cases with Thyroid Hemiagenesis: Single Centre Experience from Turkey

Abdurrahman Comlekci1 , Baris Akinci1, Tevfik Demir1, Ozhan Ozdogan1, Mustafa Secil1, Ali Saklamaz1, Serkan Yener1, Serafettin Canda1, Tulay Canda1, Sena Yesil1, Yigit Goktay11Dokuz Eylul University, Turkey

Thyroid

P56

Severe obesity accompanied with subclinical hypothyroidism.

Ketevan Asatiani1, Shota Janjgava1, Lasha Uchava1, Marina Tsagareli1, Nana Tsagareli11City Clinical Hospital N4, Endocrine Disorders Department, Georgia

Thyroid

P57

THE PSYCHOVEGETATIVE STATUS AT PATIENTS WITH POSTOPERATIVE PRIMARY HYPOTHYRIODISM, COMPENSATED BY LEVOTHYROXYN

Elena Smirnova1, Klara Shtayn1, Natalia Suhaia1, Irina Rusinova1, Julia Belikova11Perm State Medical Academy, Russian Federation

Thyroid

P58

The influence of thyroxine replacement therapy on bone mineral density in hypothyroid subjects

Snezana Polovina1 , Klara Tucic Nemet1, Ivana Pletikosic1, Angelina Obradovic11General Hospital Subotica, Serbia

Thyroid

P59

Real-time Elastography and Contrast-Enhanced Ultrasound for the Assessment of Thyroid Nodules

Mireen Friedrich-Rust1 , Andrea Sperber1, Katharina Holzer2, Frank Gruenwald3, Klaus Badenhoop1, Wolf Bechstein2, Stefan Zeuzem1, Joerg Bojunga11Department of Internal Medicine 1, J.W.Goethe- University Hospital, Germany, 2Department of General and Visceral Surgery, J.W.Goethe-University Hospital, Germany, 3Department of Nuclear Medicine, J.W.Goethe-University Hospital, Germany

Thyroid

P60

The Value of TSH-assisted 18F-FDG PET in initial Stage M0 Thyroid Carcinoma with suspicion of residual or recurrent disease

David Taïeb1 , Cecile Ghander1, Frederic Sebag1, Laurent Tessonnier1, F Fausto Palazzo1, Catherine De Micco1, Jean-François Henry1, Olivier Mundler11CHU Timone, France

Thyroid

P61

Influence of pentoxifylline on peripheral blood mononuclear cells proliferation and apoptosis in Graves’ ophthalmopathy

Irina Melnik1, Anastasiya Hlazkova1, Svetlana Kosmacheva2, Natallia Goncharova2, Larisa Danilova1, Aleksey Romanovskiy11Belarussian Medical Academy of Post-Graduate Education, Belarus, 2Republican Scientific and Practic Center for Hematology and Transfusiology, Belarus

Thyroid

P62

Soluble CD40 and its ligand CD154 in patients with Graves’ orbitopathy during combined therapy with corticosteroids and teleradiotherapy

Janusz Mysliwiec1 , Dariusz Waligorski2, Agnieszka Nikolajuk1, Maria Gorska11Department of Endocrinology, Medical University, Poland, 2Department of Endocrinology, Holycross Cancer Center, Poland

Thyroid

P63

Analysis of the genetic markers: ANLN, BIRC5, UBE2C, IRAK1, ZMYCD11, CENPA in needle aspiration cytology (FNA) of thyroid and their used as targets for molecular- diagnosis and prognostic value.

Eugenia Mato1 , Jesús Martín-Campos2, Josefina Mora3, Enrique Lerma4, Olga Bell1, Alberto de Leiva1,51Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER- BBN), Hospital Santa Creu i Sant Pau, Autonomous University, Spain, 2Department of Biochemistry and Molecular Biology. Institut de Recerca. Hospital de la Santa Creu i Sant Pau, Autonomous University, Spain, 3Department of Clinical Biochemistry, Hospital Santa Creu i Sant Pau, Autonomous University, Spain, 4Department of Pathology, Hospital de la Santa Creu i Sant Pau, Autonomous University, Barcelona, Spain, 5Endocrinology Department, Hospital Sant Pau. Autonomous University, Spain

Thyroid

P64

Association of G1201/T exon8 and A2257/C exon 12 polymorphisms with Anti-TPO titter

Mehdi Hedayati1 , Maryam Sadat Daneshpour1, Marziyeh Salehi1, Fereidoun Azizi11Research Institute for Endocrine Sciences, Iran, Islamic Republic of

Thyroid

P65

Prevalence of growth hormone deficiency in autoimmune hypothyroidism

Silvia Eskes1 , Erik Endert1, Eric Fliers1, Wilmar Wiersinga11Academic Medical Center, Netherlands

Thyroid

P66

Differences in expression pattern of all-trans retinoic acid and retinoid X nuclear receptor subtypes in papillary thyroid carcinoma: A comparison with anaplastic thyroid carcinoma.

Dana Macejova1 , Slavomira Ondkova1, Stefan Galbavy2, Jan Podoba2, Juraj Kausitz2, Julius Brtko111Institute of Experimental Endocrinology, Slovakia, 2Saint Elizabeth Institute of Oncology, Slovakia

Thyroid

P67

RAPID PREPARATION OF PATIENTS WITH HYPERTHYROIDISM FOR THYROIDECTOMY

Sinem KIYICI1 , Ozen OZ GUL1, Soner CANDER1, Turkay KIRDAK2, Oguz Kaan UNAL1, Canan ERSOY1, Ercan TUNCEL1, Erdinc ERTURK1, Sazi IMAMOGLU11Uludag University, Medical Faculty, Department of Endocrinology and Metabolism, Turkey, 2Uludag University, Medical Faculty, Department of General Surgery, Turkey

Thyroid

P68

TREATMENT OF PATIENTS WITH GRAVES’ ORBITOPATHY (GO) WITH RITUXIMAB: EFFECTS ON HUMORAL IMMUNITY

Guia Vannucchi1 , Irene Campi1, Marco Bonomi2, Nicola Currò3, Davide Dazzi1, Danila Covelli1, Paola Bonara4, Luca Persani2, Jack Wall5, Paolo Beck-Peccoz1, Mario Salvi11Department of Medical Sciences, Endocrine Unit Fondazione Policlinico IRCCS University of Milan, Italy, 2Istituto Auxologico, Italy, 3Ophthalmology, Fondazione Policlinico IRCCS, Italy, 4Internal Medicine, Fondazione Policlinico IRCCS, Italy, 5University of Sidney, Australia

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P69

Diagnostic ability of computed tomography to asses Graves ophthalmopathy

Adina Dragomir1 , Anda Dumitrascu1, Ileana Marinescu1, Constantin Dumitrache1, Anca Dalea1, Ruxandra Hristea1, Laura Iconaru1, Sabina Oros11National Institute of Endocrinology C. I. Parhon, Romania

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P70

Recombinant-human TSH (rh-TSH) testing in patients with history of thyroid microcarcinomas.

Selene Capitanio1, Francesca Cecoli1, Lorenzo Mortara1, Francesco Fiz1, Valeria Caorsi1, Francesco Minuto1, Massimo Giusti11Dipartimento di Scienze Endocrinologiche e Mediche, University of Genova, Italy

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P71

Comparison of the Analgesic Efficacy of Lidocaine/Prilocaine (EMLA) Cream and Needle-free delivery of lidocaine during the Fine-Needle Aspiration Biopsy of Thyroid Nodules

Alptekin Gürsoy1 , Cüneyd Anil1, Semra Aytürk1, Asli Nar1, Neslihan Bascil Tütüncü11Baskent University Faculty of Medicine, Department of Endocrinology and Metabolism, Turkey

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P72

The role of anti-DNA antibodies in pathogenesis of Hashimoto’s thyroiditis.

Gulnar Vagapova1,2 , Lilya Sattarova21Kazan State Medical Academy, Russian Federation, 2Interregional Clinical Diagnostic Centre, Russian Federation

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P73

Effects of 900 MHz electromagnetic fields emitted from cellular phone on T3, T4 and cortisol hormones of Syrian Hamsters ( Mesocricetus auratus )

habib aghdam shahryar, Alireza Lotfi11Islamic azad university, shabestar branch, Iran, Islamic Republic of

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P74

The effect of overt and subclinical hypothyroidism on the development of nondipper blood pressure pattern

Salih Inal2 , Mehmet Ayhan Karakoç1, Erdal Kan1, Füsun Balos Törüner1, Metin Aslan11Gazi University Hospital, Faculty of Medicine, Department of Endocrinolgy and Metabolism, Turkey, 2Gazi University Hospital, Faculty of Medicine, Department of Internal Medicine, Turkey

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P75

Influence of thiamazole, lithium carbonate or prednisone administration on the efficacy of radioiodine treatment (131I) in hyperthyroid patients

Lidia Oszukowska1, Malgorzata Knapska-Kucharska1, Malgorzata Karbownik-Lewinska2,4, Andrzej Lewinski3,41Department of Nuclear Medicine and Oncological Endocrinology, Medical University, Poland, 2Department of Oncological Endocrinology, Medical University, Poland, 3Department of Endocrinology and Metabolic Diseases, Medical University, Poland, 4Polish Mother’s Memorial Hospital – Research Institute, Poland

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P76

BRAFV600E MUTATION AND TIMP-1 HYPER-EXPRESSION IN CLASSICAL VARIANTS OF PAPILLARY THYROID CARCINOMA (PTC)

Alessandra Bommarito1 , Elvira Carissimi1, Pierina Richiusa1, Marco Calogero Amato1, Leonardo Russo1, Giovanni Zito1, Giuseppe Pizzolanti1, Carla Giordano11University of Palermo, Italy

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P77

Analysis of Sonic Hedgehog gene in patients with thyroid hemiagenesis – preliminary report

Ewelina Szczepanek1 , Marek Ruchala1, Witold Szaflarski2, Bartlomiej Budny3, Michal Nowicki2, Maciej Zabel2, Jerzy Sowinski11Department of Endocrinology, Metabolism and Internal Medicine, University of Medical Sciences, Poland, 2Department of Histology and Embriology, University of Medical Sciences, Poland, 3Department of Medical Genetics, University of Medical Sciences, Poland

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P78

VALUE OF ULTRASOUND ELASTOGRAPHY OF THE THYROID GLAND IN DIFFERENTIATING MALIGNANT NODULES

Cristina Ghervan1 , Dana Dumitriu2, Sorin Dudea2, Valentin Muntean3, Ileana Duncea11University of Medicine and Pharmacy - Endocrinology Dept., Romania, 2University of Medicine and Pharmacy - Radiology Dept., Romania, 3University of Medicine and Pharmacy - Surgery IV Dept, Romania

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P79

Autoimmune Thyroiditis- Ultrasound Phenotypes in 1500 patients

Dan Peretianu1 , Mara Carsote2, Andrei Goldstein3, Corina Chirita31SCM Povernei, Romania, 2Carol Davila University of Medicine and Pharmacy, Romania, 3CI Parhon National Institute of Endocrinology, Romania

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P80

Association between BMI and serum TSH in euthyroid subjects: The Tehran Thyroid Study

atieh Amouzegar1,2 , farhad Hosseinpanah1, fereidoun Azizi11Research Institute of Endocrine Science, Iran, Islamic Republic of

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P81

PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-γ (PPARγ) EXPRESSION IN PARATHYROID ADENOMAS IN PRIMARY HYPERPARATHYROIDISM.

Güngör Akçay1 , Müfide Nuran Akçay2, Remzi Arslan31University of Atatürk,School of Medicine,Department of Internal Medicine,Division of Endocrinology of, Turkey, 2University of Atatürk,School of Medicine,Department of Surgery, Turkey, 3University of Atatürk,School of Medicine,Department of Pathology, Turkey

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P82

SOMATOSTATIN RECEPTOR 2 EXPRESSION IN COLD THYROID NODULES EXCEEDS THAT OF HOT THYROID NODULES, PAPILLARY THYROID CARCINOMA AND GRAVES’ DISEASE

Seda Sancak1 , Anna Hardt2, Jörg Singer2, G. Klöppel3, Funda Tanay Eren4, Leyla Semiha Sen5, Bahadir M. Güllüoglu5, Zeynep Sever4, N.Sema Akalin1, Markus Eszlinger2, Ralf Paschke21Section of Endocrinology and Metabolism of Marmara Medical School, Turkey, 2IIIrd Medical Department, University of Leipzig, Germany, 3University Clinic Schleswig-Holstein, Germany, 4Department of Pathology of Marmara Medical School, Turkey, 5General Surgery Department of Marmara Medical School, Turkey

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P83

The role of repeat fine-needle aspiration biopsy (FNAB) in the management of thyroid nodule

Ignasi Castells1 , Nuria Pardo1, Gabriel Gimenez1, Olga Simo1, Asumpta Recasens1, Guzman Franch1, Xavier Guirao1, Angel Serrano11Hospital General de Granollers, Spain

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P84

CLINICOPATHOLOGIC FEATURES OF INCIDENTAL AND NONINCIDENTAL PAPILLARY THYROID MICROCARCINOMA

UFUK OZUGUZ1 , DILEK BERKER1, YUSUF AYDIN1, SERHAT ISIK1, YASEMIN TUTUNCU1, TUNCAY DELIBASI1, SERDAR GULER11S.B. ANKARA NUMUNE RESEARCH AND TRAINING HOSPITAL, ENDOCRINOLOGY AND METABOLISM CLINIC, Turkey

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P85

IS THERE ANY BENEFICIAL EFFECT OF L-THYROXINE REPLACEMENT THERAPHY ON CARDIOVASCULAR RISK FACTORS IN PATIENTS WITH SUBCLINICAL HYPOTHYROIDISM?

Oguz Kaan Ünal1 , Erdinc Erturk1, Emre Sarandöl2, Esma Eröz2, Sinem Kiyici1, Metin Güclü1, Sazi Imamoglu11Endocrinology and Metabolism Department, Uludag University, Faculty of Medicine, Turkey, 2Biochemistry, Uludag University, Faculty of Medicine, Turkey

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P86

A comprehensive surgical approach of persistent cervical papillary thyroid carcinoma based on initial surgery and modern preoperative imaging modalities

Fares Benmiloud1 , David Taieb1, Frederic Sebag1, Jean-François Henry11La Timone Hospital, France

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P87

LONG-TERM EXOGENOUS SUBCLINICAL HYPERTHYROIDISM IS NOT ASSOCIATED WITH DECRASED BONE MINERAL DENSITY IN MEN WITH DIFFERENTIATED THYROID CARCINOMA.

Eulàlia Colomé1 , Jordi L. Reverter1, Susana Holgado2, Rocio Puig1, Núria Alonso1, Anna Sanmartí11Department of Endocrinology and Nutrition. Germans Trias i Pujol University Hospital, Spain, 2Department of Reumathology. Germans Trias i Pujol University Hospital, Spain

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P88

What is the outcome of combined therapies in amiodarone-induced thyrotoxicosis?

Raluca-Alexandra Trifanescu1,2 , Horea Ursu1,2, Mariana Purice21"Carol Davila" University of Medicine and Pharmacy, Romania, 2"C.I.Parhon" Institute of Endocrinology, Romania

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P89

Our Experience in Visualization of Non-Radioiodine-Avid Differentiated Thyroid Carcinoma (NRADTC)

Zbigniew Podgajny1 , Grzegorz Kaminski1, Norbert Szalus21Endocrinology and Radioisotope Therapy Department – Military Institute of Health Services, Poland, 2Nuclear Medicine Department – Military Institute of Health Services, Poland

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P90

Long-term follow-up of antithyroid peroxidase antibodies in patients with Hashimoto's thyroiditis

Kemal Agbaht1 , Iffet Dagdelen1, Sevim Gullu11Ankara University, Faculty of Medicine, Endcorinology and Metabolic Diseases, Turkey

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P91

EVALUATION OF CHRONIC URTICARIA IN PATIENTS WITH AUTOIMMUNE THYROID DISEASE

Evangeline Vassilatou1 , Dimitrios Hadjidakis1, Anagnostis Mellios2, Michael Makris2, Ekaterini Chliva2, Theophanis Economopoulos1, Dimitrios Kalogeromitros21Endocrine Unit, 2nd Dpt of Internal Medicine, Attikon University Hospital, Greece, 2Allergy Clinical Research Center, Allergy Unit, Attikon University Hospital, Greece

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P92

AUTOIMMUNE THYROIDITIS, GRAVES’ DISEASE AND CARDIOVASCULAR RISK FACTORS

Celestino Neves1 , Marta Alves1, Luís Miguel Pereira1, Ema Carvalho1, Isolina Pimentel1, Renata Carvalho2, Cristina Guimarães2, João Pedro Ramos2, Davide Carvalho1, José Luís Delgado2, José Luís Medina11Endocrinology Service, S. João Hospital, Faculty of Medicine, University of Porto, Portugal, 2Immunology Service, S. João Hospital, Faculty of Medicine, University of Porto, Portugal

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P93

CURRENT IODINE STATUS IN TURKEY

Murat Faik Erdogan1 , Kemal Agbaht1, Tanju Altunsoy2, Sema Ozbas2, Fatma Yucesan2, Basak Tezel2, Canan Sargin3, Ibrahim Ilbeg4, Nevzat Artik4, Rifat Kose2, Gurbuz Erdogan11Ankara University, Faculty of Medicine, Department of Endocrinology and Metabolism, Turkey, 2The Ministry of Health of Turkey, Directorship of Health of Mother and Child and Family Planning, Turkey, 3UNICEF-Turkey, Turkey, 4The Ministry of Agriculture of Turkey, Directorship of Prevention and Control, Turkey

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P94

RESULTS OF THE 2007 FOLLOW-UP MONITORING SURVEY FOR IODINE STATUS IN TURKEY

Murat Faik Erdogan1 , Kemal Agbaht1, Tanju Altunsoy2, Sema Ozbas2, Fatma Yucesan2, Basak Tezel2, Canan Sargin3, Ibrahim Ilbeg4, Nevzat Artik4, Rifat Kose2, Gurbuz Erdogan11Ankara University Faculty of Medicine Endcorinology and Mebolic Diseases, Turkey, 2The Ministry of Health of Turkey, Directorship of Health of Mother and Child and Family Planning, Turkey, 3UNICEF-Turkey, Turkey, 4The Ministry of Agriculture of Turkey, Directorship of Prevention and Control, Turkey

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P95

Evaluation of metabolic and endocrine complications in β-Thalassemia major. Cross sectional study of 65 patients.

Farzad Najafipour1 , Amir Bahrami11Endocrinology and Metabolism section, Department of Medicine, Tabriz University of Medical sciences, Iran, Islamic Republic of

Thyroid

P96

When Antithyroid Drugs Must be Started in Patients with Hyperemesis Gravidarum?

Farzad Najafipour1 , Amir Bahrami11Department of Endocrinology and Metabolisem, Emam Reza Hospital, Tabriz University of Medical sciences,, Iran, Islamic Republic of

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P97

Frequency of Metabolic Syndrome in Hypothyroid Patients

Sencer Ganidagli1, Mehmet Erdogan2, Aybike Kosenli1, Mustafa Kulaksizoglu3, Soner Solmaz1, Nebi Sokmen4, Abdullah Canataroglu11Numune Education and Research Hospital, Department of Internal Medicine, Turkey, 2Ege University Medical School, Department of Endocrinology and Metabolism Disease, Turkey, 3Numune Education and Research Hospital, Department of Endocrinology, Turkey, 4Numune Education and Research Hospital, Department of Family Practice, Turkey

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P98

Lipid oxidation, antioxidants and paraoxonase enzyme activity in subclinical thyrotoxicosis.

Mehrdad Solati1 , Ladan Atai2, Fereidoun Azizi21Hormozgan University of Medical Sciences, Iran, Islamic Republic of, 2Shahid Beheshti University of Medical Sciences, Iran, Islamic Republic of

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P99

THE PREVALENCE AND THE SIGNIFICANCE OF NODULAR THYROID DISEASE (NTD) IN THYROID AUTOIMMUNE DISEASE (TAD)

IOANA ZOSIN1 , MARIOARA CORNIANU2, MIHAELA VLAD1, MELANIA BALAS1, IOANA GOLU1, DANIELA AMZAR1, ROLAND SCHMIDT11DEPARTMENT OF ENDOCRINOLOGY,UNIVERSITY OF MEDICINE AND PHARMACY, Romania, 2DEPARTMENT OF MORPHOPATHOLOGY, UNIVERSITY OF MEDICINE AND PHARMACY, Romania

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P100

Correlation of sonographic findings with thyroid function and autoimmune activity in patients with vitiligo

parvin layegh1 , pouran layegh1, masoud pezeshki rad1, ahmad sahebalam1, parvaneh layegh1, mohammad taghi shakeri11Mashhad university of medical sciences, Iran, Islamic Republic of

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P101

Thyroid node pathology: correlation between cytology, histology and radiology using a new cytological classification

Ignasi Castells1 , Nuria Pardo1, Guzman Franch1, Olga Simo1, Asumpta Recasens1, Xavier Guirao1, Gabriel Gimenez11Hospital General de Granollers, Spain

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P102

Levothyroxine suppression treatment for benign thyroid nodules alters coagulation

Tevfik Demir1, Baris Akinci1, Abdurrahman Comlekci1, Oguzhan Karaoglu1, Mehmet Ali Ozcan1, Serkan Yener1, Faize Yuksel1, Mustafa Secil1, Sena Yesil11Dokuz Eylul University, Turkey

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P103

The role of Large-neddle biopsy (LNB) in thyroid nodules. Validation with surgical results in more than 100 cases.

Miguel Paja1 , Josu Pérez-Yéboles1, Maider Sánchez1, Ana Izuzquiza1, Estíbaliz Ugarte1, Rosa Zabala2, Jose I. López3, Amelia Oleaga11Endocrinología. Hospital de Basurto, Spain, 2Radiología. Hospital de Basurto, Spain, 3Anatomía Patológica. Hospital de Basurto, Spain

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P104

CA 19-9 LEVELS IN HASHIMOTO’S THYROIDITIS

Kerem Sezer1 , Mesut Ozkaya2, Erman Cakal3, Esen Akbay11Department of Endocrinology and Metabolic Diseases, School of Medicine, Mersin University, Turkey, 2Department of Endocrinology and Metabolic Diseases, School of Medicine, Sutcuimam University, Turkey, 3Department of Endocrinology and Metabolic Diseases, Yuksek Ihtisas Hospital, Turkey

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P105

NO ASSOCIATON OF CTLA-4 GENE POLYMORPHISM WITH GRAVES’ DISEASE IN TURKISH POPULATION

Leyla Kilic1 , Sema Yarman1, Burcak Vural2, Ugur Ozbek21Division of Endocrinology and Metabolism, Department of Internal Medicine,Istanbul University, Istanbul Faculty of Medicine, Turkey, 2Experimental Medicine Reseach Center, Istanbul University, Istanbul Faculty of Medicine, Turkey

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P106

THE RATIO OF MALIGNANCY IN PATIENTS WHO UNDERWENT THYROIDECTOMY DUE TO FOLLICULAR LESION/NEOPLASIA

Kamile GUL1 , Didem Ozdemir SEN1, Husniye BASER1, Ali ERKAN2, Reyhan ERSOY1, Bekir CAKIR11Ankara Ataturk Education and Research Hospital, Department of Endocrinology and Metabolism, Turkey, 2Ankara Ataturk Education and Research Hospital, Department of 2. General Surgery, Turkey

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P107

CONCOMITANT THYROID CARCINOMA AND HASHIMOTO THYROIDITIS: EFFECT OF THYROIDITIS ON ULTRASONOGRAPHIC AND HISTOPATHOLOGIC FEATURES OF NODULES

Kamile GUL1 , Dilek TUZUN1, Ahmet DIRIKOC1, Gulten KIYAK1,2, Reyhan ERSOY1, Bekir CAKIR11Ankara Ataturk Education and Research Hospital, Department of Endocrinology and Metabolism, Turkey, 2Ankara Ataturk Education and Research Hospital, Department of 2.General Surgery, Turkey

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P108

Quality of life changes, clinical outcomes and radiation protection issues in thyroid cancer patients undergoing radioiodine remnant ablation with recombinant human thyrotropin: a randomized controlled study.

Taïeb David1 , Sebag Frederic1, Cherenko Maria1, Baumstarck-Barrau Karine1, Bardia Farman-Ara1, Catherine De Micco1, Jean François henry1, Olivier Mundler11CHU Timone, France

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P109

Incidental and nonincidental papillary thyroid microcarcinomas in the material of Endocrinology Clinic and Institute of Pathology Targu Mures

Zsuzsanna Szanto1 , Imre Zoltan Kun1, Janos Jung21Endocrinology Clinic, Romania, 2Institute of Pathology, Romania

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P110

ERYTHROXYTE MEMBRANE CHOLESTEROL CONCENTRATION IN PATIENTS WITH HYPERTHYROIDISM

Constantinos Lempesopoulos1, Constantinos Timbas2, Georgeta Parvouleskou2, Athanasios Yalouris21A.FLEMING GENERAL HOSPITAL, Greece, 2ELPIS GENERAL HOSPITAL, Greece

Thyroid

P111

ASSOCIATION OF THYROID FUNCTION TESTS WITH THYROID MALIGNANCY

Kamile GUL1 , Reyhan ERSOY1, Ahmet DIRIKOC1, Ayten OGUZ1, Dilek TUZUN1, Husniye BASER1, Bekir CAKIR11Ankara Ataturk Education and Research Hospital, Department of Endocrinology and Metabolism, Turkey

Thyroid

P112

PREOPERATIVE THYROID PROBLEMS IN A CARDIOVASCULAR HOSPITAL

Dilek Yazici1 , Eylem Tuncer2, Ilker Mataraci2, Vedat Erentug21Kartal Kosuyolu Heart Education and Research Hospital, Section of Endocrinology and Metabolism, Turkey, 2Kartal Kosuyolu Heart Education and Research Hospital, Department of Cardiovascular Surgery, Turkey

Thyroid

P113

The changes of the IL-2,IL-4,IL-12, TNF-α and IFN-γ levels with L-thyroxine treatment in patients with Hashimoto's throiditis. Feyzullah Güçlü 1, Bilgin Özmen 2, Cengiz Kırmaz 3, Sabriye Kafesçiler 2, Fatma Taneli 4, Zeliha Hekimsoy 2 Antakya Government Hospital, Department of Endocrinology 1, Antakya, Turkey Celal Bayar University Faculty of Medicine, Department of Endocrinology 2, Allergy – Immunology 3 and Biochemistry 4 , Manisa, Turkey

Feyzullah Güçlü1 , Bilgin Özmen2, Cengiz Kirmaz2, Sabriye Kafesçiler2, Fatma Taneli2, Zeliha Hekimsoy21Antakya Government Hospital, Department of Endocrinology, Turkey, 2Celal Bayar University Faculty of Medicine, Department of Endocrinology, Turkey

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P114

Analysis of demographic and clinical factors, affecting the outcome of radioiodine therapy in patients with hyperthyroidism

Malgorzata Kanpska-Kucharska1, Lidia Oszukowska1, Malgorzata Karbownik-Lewinska2,4, Andrzej Lewinski3,41Department of Nuclear Medicine and Oncological Endocrinology, Medical University, Poland, 2Department of Oncological Endocrinology, Medical University, Poland, 3Department of Endocrinology and Metabolic Diseases, Medical University, Poland, 4Polish Mother’s Memorial Hospital – Research Institute, Poland

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P115

THYROID FUNCTION AND VOLUME DISORDERS CORRELATES WITH IQ IN MENTAL RETARD CHILDREN (interim report)

Hamid Reza Bazrafshan , Syrous Vahedi3, Ghiam Jafari2, Ali Reza Maleki21Department of endocrinology,Golestan university of medical sciences, Iran, Islamic Republic of, 2Faculty of medicine,Golestan university of medical sciences, Iran, Islamic Republic of, 3Assistant professor of clinical radiology, Azad university of medical sciences, Iran, Islamic Republic of

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P116

Application of flow cytometry for evaluation of the phenotype of lymphocytes, present in the thyroid glands of patients with lymphoma in extrathyroid localisation

Zbigniew Adamczewski 1,2, Jan Dabrowski1,2, Andrzej Lewinski1,21Department of Endocrinology and Metabolic Diseases, Medical University, Poland, 2Polish Mother's Memorial Hospital - Research Institute, Poland

Thyroid

P117

SUBJECTIVE AND OBJECTIVE SLEEP EVALUATION IN PATIENTS WITH HYPO- AND HYPER- THYROIDISM

Fabrizio Riganti1 , Fabiana Di Noi1, Maria Angela Seardo1, Elena Gramaglia1, Nadia Bonelli1, Ruth Rossetto1, Ezio Ghigo1, Fabio Broglio11Division of Endocrinology, Department of Internal Medicine, University of Turin, Italy

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P118

Demographic, Clinical, Laboratory, Ultrasonographic and Cytological Features of Patients with Hashimoto’s Thyroiditis: results of a university hospital of 769 patients in Turkey

Mehmet Erdogan1 , Nihat Erdem2, Sevki Cetinkalp1, Gokhan Ozgen1, Fusun Saygili1, Candeger Yilmaz1, Mehmet Tuzun1, Taylan Kabalak11Ege University Faculty of Medicine, Department of Endocrinology and Metabolism, Turkey, 2Ege University, Department of Internal Medicine, Turkey

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P119

Assessment of the thyroid hormone’s profile during pregnancy

Alicja Hubalewska-Dydejczyk1, Marta Kostecka- Matyja1, Dorota Pach1, Monika Buziak-Bereza1, Malgorzata Trofimiuk1, Justyna Gil1, Edyta Polak11Department and Clinic of Endocrinology, Poland

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P120

Seasonal occurrence of Graves’ disease and associated orbitopathy at diagnosis.

Irene Campi1 , Guia Vannucchi1, Danila Covelli1, Nicola Currò2, Davide Dazzi1, Paolo Beck-Peccoz1, Mario Salvi11Department of Medical Sciences, Endocrine Unit, University of Milan, Fondazione Policlinico IRCCS, Italy, 2Ophthalmology, University of Milan, Fondazione Policlinico IRCCS, Italy

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P121

The incidence of thyroid cancer in the North-Eastern Region of Poland: a twelve year follow-up.

Anna Zonenberg1 , Beata Telejko1, Agnieszka Nikolajuk1, Katarzyna Siewko1, Lech Zimnoch2, Jacek Dadan3, Ida Kinalska1, Maria Górska11Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, Poland, 2Department of Clinical Pathomorphology, Medical University of Bialystok, Poland, 3Department of General Surgery, Medical University of Bialystok, Poland

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P122

The TSH receptor antibody levels (TSHRAb) and thyroid function after 131I therapy in patients with Graves’ disease - 10 years follow-up.

Jolanta Kijek1 , Jerzy S. Tarach2, Maria Kurowska2, Bozena Szymanek11Department of Nuclear Medicine, Medical University, Poland, 2Department of Endocrinology, Medical University, Poland

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P123

The outcome of radioiodine therapy in Graves’ hyperthyroidism – thyroid size as prognostic factor.

Jolanta Kijek1 , Jerzy S. Tarach2, Maria Kurowska2, Helena Jankowska11Department of Nuclear Medicine, Medical University, Poland, 2Department of Endocrinology, Medical University, Poland

Thyroid

P124

PROGNOSTIC ROLE OF SUB-CLINICAL HYPOTHYROIDISM IN CHRONIC HEART FAILURE OUTPATIENTS

Edoardo Guastamacchia1 , Vincenzo Triggiani1, Massimo Iacoviello2, Pietro Guida2, Cinzia Forleo2, Raffaella Catanzaro2, Emilio Tafaro1, Stefano Favale21Endocrinology and Metabolic Diseases. University of Bari, Italy, 2Cardiology. University of Bari, Italy

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P125

Cognitive functions and concentrations of thyroid hormones and thyrotropin in hyperthyroidism in the course of Graves’ disease

Karolina Jablkowska1 , Katarzyna Nowakowska1, Joanna Klubo-Gwiezdzinska2, Roman Junik2, Alina Borkowska11Department of Medical Psychology, Poland, 2Department of Endocrinology and Diabetology, Nicolaus Copernicus University in Torun, Collegium Medicum in Bydgoszcz, Poland

Thyroid

P126

ANTITUMOR EFFECTS OF AMINOBISPHOSPHONATES ON ANAPLASTIC THYROID CARCINOMA CELL LINES

Maria Pitrone1 , Giovanni Zito1, Elvira Carissimi1, Alessandra Bommarito1, Pierina Richiusa1, Aldo Galluzzo1, Carla Giordano1, Giuseppe Pizzolanti1, V Bullara11University of Palermo, Lab. of Molecular Endocrinology, DOSAC, Italy

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P127

CHRONIC AUTOIMMUNE THYROIDITIS - MORPHO-FUNCTIONAL AND IMMUNOLOGICAL ASPECTS

Corina Crista1 , Ioana Zosin1, Otilia Marginean2, Ioana Micle21Clinic of Endocrinology, University of Medicine and Pharmacy, Romania, 2Ist Pediatric Clinic, “Louis Turcanu” Children Hospital, Romania

Thyroid

P128

Coexistence of hyperparathyroidism and non-medullary thyroid carcinoma

Leonidas Alevizos1 , Haridimos Markogiannakis1, Panagiotis Kekis1, Artemisia Papadima1, Frantzeska Sigala1, Konstantinos Filis1, Konstantinos Toutouzas1, Andreas Manouras11Department of Endocrine Surgery, 1st Department of Propaedeutic Surgery, Hippokrateion Hospital, Athens Medical School, University of Athens, Greece

Thyroid

P129

The effect of radioiodine therapy in patients with non toxic goitre

Saeid Abdelrazek1 , Franciszek Rogowski1, Anna Zonenberg2, Maria Maria Gorska2, Malgorzata Malgorzata Szelachowska2, Piotr Piotr Szumowski1, Malgorzata Malgorzata Frackiel2, Katarzyna Siewko2, Malgorzata Malgorzata Karolczuk-Zarachowicz21Department of Nuclear Medicine, Medical University of Bialystok, Poland, 2Department of Endocrinology, Diabetology and Internal Medicine Medical University of Bialystok, Poland

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P130

A Case of Complete Deficiency of Total Thyroxine-binding Globulin (TBG) Associated with Graves' Disease

DOO-MAN KIM1 , HYEON KYU KIM1, SOON JIB YOO21Department of Internal Medicine, Hallym University College of Medicine, Korea, Republic of, 2Department of Internal Medicine, College of Medicine, Catholic University, Korea, Republic of

Thyroid

P131

REGRESSION OF PULMONARY ARTERIAL HYPERTENSION AFTER TREATMENT OF HYPERTHYROIDISM

Ana Rosa Quidute1, Joyce Paiva1, Virgínia Fernandes1, Clarisse Ponte1, Rejane Magalhães1, Renan Montenegro1, Ana Gardênia Farias2, Carlos Roberto Rodrigues Sobrinho2,4, Renan Montenegro Júnior1,31Endocrinology and Diabetes Service, Walter Cantídio University Hospital,Federal University of Ceará, Brazil, 2Cardiology Service, Walter Cantídio University Hospital,Federal University of Ceará, Brazil, 3Comunity Health Department, Faculty of Medicine, Federal University of Ceará, Brazil, 4Clinical Medicine Department, Faculty of Medicine, Federal University of Ceará, Brazil

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P132

THYROID FUNCTION, SERUM LIPIDS AND INSULIN RESISTANCE IN PATIENTS WITH AUTOIMMUNE THYROIDITIS

Celestino Neves1 , Marta Alves1, Luís Miguel Pereira1, Isolina Pimentel1, Ema Carvalho1, Renata Carvalho2, Cristina Guimarães2, João Pedro Ramos2, Davide Carvalho1, José Luís Delgado2, José Luís Medina11Endocrinology Service, S. João Hospital, Faculty of Medicine, University of Porto, Portugal, 2Immunology Service, S. João Hospital, Faculty of Medicine, University of Porto, Portugal

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P133

Association of HTLV-I with autoimmune thyroiditis in patients with myelopathy/tropical spastic paraparesis and in HTLV-I carriers in Mashhad, North East of Iran

Morteza Taghavi11Ghaem Hospital, Mashhad Medical Science University, Iran, Islamic Republic of

Thyroid

P134

INFLUENCE OF THYROMETABOLIC STATE ON DISTRIBUTION OF SUBPOPULATIONS AND FENOTYPES OF DENDRITIC CELLS IN PERIPHERAL BLOOD OF THE PATIENTS WITH CHRONIC THYROIDITIS AND PATIENTS MONITORED BECAUSE OF DIFFERENTIATED THYROID CANCER

Marek Dedecjus1 , Mariusz Stasiolek2, jan Brzezinski3, Krzysztof Selmaj2, Andrzej Lewinski41Department of General and Endocrine Surgery, Chair of Endocrinology and Metabolic Diseases, Medical University of Lodz, Polish Mother's Memorial Hospital - Research Institute, Poland, 2Department of Neurology, Medical University of Lodz, Poland, 33Department of General and Endocrine Surgery, Chair of Endocrinology and Metabolic Diseases, Medical University of Lodz, Polish Mother's Memorial Hospital - Research Institute, Poland, 44Department of Endocrinology and Metabolic Diseases, Chair of Endocrinology and Metabolic Diseases, Medical University of Lodz, Polish Mother's Memorial Hospital - Research Institute, Poland

Thyroid

P135

EVALUATION OF CYCLINS A AND B1 EXPRESSION IN CLASSICAL AND NONCLASSICAL VARIANTS OF PAPILLARY THYROID CARCINOMA

M Naze 1 , M Dedecjus1, O Stasikowska2, S Sporny2, J Brzezinski111Department of General and Endocrine Surgery, Medical University of Lodz, Polish Mother’s Memorial Hospital – Research Institute, Poland, 22Department of Pathomorphology, Medical University of Lodz, Poland

Thyroid

P136

Alterations in TSH and Thyroid Hormones Following Mobile Phone Use

S Mohammad J Mortazavi, Asadollah Habib1, AH Ganj-Karimi1, Razieh Samimi Doost11Rafsanjan University of Medical Sciences, Iran, Islamic Republic of

Thyroid

P137

Prevalence of Thyroid Dysfunction in the Elderly women of Iran

mitra niafar1 , akbar Aliasgharzadeh1, amir bahrami1, farzad Najafipur11Tabriz University of Medical sciences, Iran, Islamic Republic of

Thyroid

P138

Experimental method of post-surgery hypothyroidism treatment

Sergey Astapenko1, Olexandr Kostyrnoy1, Olexandr Butyrsky1, Dmytro Shestopalov11crimean state medical university, Ukraine

Thyroid

P139

PHYSICAL AND PYSCHOLOGICAL WELL-BEING IN ADULTS WITH THYROID ANORMALITIES

Gideon Mlawa1 , Charles Bodmer2,1, Ryod D'Souza11COLCHESTER HOSPITAL, United Kingdom, 2COLCHESTER HOSPITAL, United Kingdom, 3CHASEFARM HOSPITAL, United Kingdom

Thyroid

P140

Anemia frequency and etiology in primary hypothyroidism

Aybike Kosenli1, Mehmet Erdogan2, Sencer Ganidagli1, Mustafa Kulaksizoglu3, Soner Solmaz1, Ozgun Kosenli4, Cagatay Unsal5, Abdullah Canataroglu11Numune Education and Research Hospital, Department of Internal Medicine, Turkey, 2Ege University Medical School, Department of Endocrinology and Metabolism Disease, Turkey, 3Numune Education and Research Hospital, Department of Endocrinology, Turkey, 4Numune Education and Research Hospital, Department of Emergency Medicine, Turkey, 5Numune Education and Research Hospital, Department of Hemotology, Turkey

Thyroid

P141

Thyrotropin suppression by metformin in a cohort of patients with differentiated thyroid cancer in follow-up

ROBERTO CITARRELLA1 , LUCIANA PULEO1, FRANCESCO CHIOFALO1, LUCIA SMERALDI1, MIRIAM NUCERA1, PIERINA RICHIUSA11Endocrinology Section of Universitary Policlinic, Italy

Thyroid

P142

Human Thyroid Tissue HCO-3-ATPase in Norm and Pathology

Nana Koshoridze1 , Manana Chipashvili1, Keti Menabde1, Zurab Kuchukashvili11Tbilisi Iv. Javakhishvili State University, Georgia

Thyroid

P143

Clinical and epidemiological characteristics of thyroid hemiagenesis: Ultrasound screening in patients with thyroid disease and normal population.

Alptekin Gürsoy1 , Cüneyd Anil1, Asli Dogruk Ünal1, Asli Nar1, Neslihan Bascil Tütüncü1, Murat Faik Erdogan21Baskent University, Faculty of Medicine, Department of Endocrinology and Metabolism, Turkey, 2Ankara University, Faculty of Medine, Department of Endocrinology and Metabolism, Turkey

Thyroid

P144

Targeted high-risk case finding of thyroid dysfunction in an Iranian pregnant population

Khatereh Mahoori1, Mohsen Dehghani Zahedani1, Azadeh Azinfar1, Mehrdad Solati11Hormozgan University of Medical Sciences, Iran, Islamic Republic of

Thyroid

P145

ASSESSMENT OF BIOCHEMICAL PARAMETERS DURING LEVOTHYROXINE REPLACEMENT THERAPY IN HYPOTHYROID PATIENTS

Romana Mijovic1, Milica Medic-Stojanoska2, Nikola Curic1, Stanislava Tonic1, Branka Kovacev-Zavisic2, Ljiljana Djilas-Todorovic21Center for laboratory medicine, Clinical Center of Vojvodina, Serbia, 2Clinic for Endocrinology, Diabetes and Metabolic Disease, Clinical Center of Vojvodina, Serbia

Thyroid

P146

NONDIAGNOSTIC FINE NEEDLE ASPIRATION BIOPSY RESULTS

Kamile GUL1 , Cevdet AYDIN1, Fevzi BALKAN1, Ali ERKAN2, Reyhan ERSOY1, Bekir CAKIR11Ankara Ataturk Education and Research Hospital, Department of Endocrinology and Metabolism, Turkey, 2Ankara Ataturk Education and Research Hospital, Department of 2.General Surgery, Turkey

Thyroid

P147

CONCURRENCY OF PRIMARY HYPERPARATHYROIDISM AND THYROID DISEASES

Kamile GUL1 , Reyhan ERSOY1, Birol KORUKLUOGLU2, P. Eren ERSOY3, Raci AYDIN4, Olcay K. BELENLI5, Nevzat Serdar UGRAS5, Bekir CAKIR11Ankara Ataturk Education and Research Hospital, Department of Endocrinology and Metabolism, Turkey, 2Ankara Ataturk Education and Research Hospital, Department of 2.General Surgery, Turkey, 3Ankara Ataturk Education and Research Hospital, Department of 3.General Surgery, Turkey, 4Ankara Ataturk Education and Research Hospital, Department of 1.General Surgery, Turkey, 5Ankara Ataturk Education and Research Hospital, Department of Pathology, Turkey

Thyroid

P148

INCIDENTAL THYROID CARCINOMA IN PATIENTS WITH THYROTOXICOSIS

SERHAT ISIK1 , DILEK BERKER1, YUSUF AYDIN1, UFUK OZUGUZ1, GULHAN AKCIL1, TUNCAY DELIBASI1, SERDAR GULER11S.B. ANKARA NUMUNE RESEARCH AND TRAINING HOSPITAL, ENDOCRINOLOGY AND METABOLISM CLINIC, Turkey

Thyroid

P149

The influence of radioiodine therapy on some parameters of oxidant/antioxidant balance in patients with toxic nodular goitre.

Saeid Abdelrazek1 , Franciszek Rogowski1, Anna Zonenberg2, Malgorzata Szelachowska2, Maria Gorska2, Agnieszka Nikolajuk2, Adam Parfienczyk1, Piotr Szumowski1, Malgorzata Frackiel1, Malgorzata Karolczuk-Zarachowicz21Department of Nuclear Medicine, Medical University of Bialystok, Poland, 2Department of Endocrinolog diabetology and internal medicine, Medical University of Bialystok, Poland

Thyroid

P150

FEVER IN THE DEBUTE OF THE DIFFUSE TOXIC GOITER

Tamara KAMYNINA1 , Valeria GUBKINA1, Alexander DREVAL11Moscow Regional Research Clinical Institute, Russian Federation

Thyroid

P151

Efficacy RAI patients with Graves disease using different methods colculation of optimum therapeutic activiti I131

Olga Nechaeva1 , Alexander Dreval1, Irina Chikh1, Irina Komerdus1, Tatiana Shestakova11Moscow Regional Recerth Clinical Institute, Russian Federation

Thyroid

P152

Comparing the Outcome of radioactive iodine treatment for hyperthyroidism in a Jordanian and British cohorts.

AHMAD OMARI1, FARES HADDAD1, OMAR MALKAWI1, JONATHAN THAW1, PAUL JENNINGS11KING HUSSEIN MEDICAL CENTER, Jordan, 2YORK DISTRICT HOSPITAL, United Kingdom

Thyroid

P153

PRIMARY HYPERPARATHYROIDISM AND SYNCHRONOUS THYROID DISORDERS: A SINGLE CENTER EXPERIENCE

Arzu Gedik1, Duygu Yazgan Aksoy1, Ayla Harmanci1, Bulent Okan Yildiz1, Miyase Bayraktar11Hacettepe University, Turkey

Thyroid

P154

Primary thyroid lymphomas

Amada Guimón1 , Dolores Moure1, Teresa Ruiz de Azua1, Javier Santamaría1, Sonia Gaztambide11Hospital de Cruces, Spain

Thyroid

P155

Iodine metabolism in hyperthyroidism.

Jolanta Kijek1 , Jerzy S. Tarach2, Maria Kurowska2, Beata Chrapko11Department of Nuclear Medicine, Medical University, Poland, 2Department of Endocrinology, Medical University, Poland

Thyroid

P156

ANALYSIS OF GHRELIN AND OBESTATIN LEVELS IN CHILDREN WITH THYROID DISEASE

Artur Bossowski1 , Beata Sawicka1, Mieczyslaw Szalecki2, Miroslawa Urban1, Franciszek Rogowski3, Alicja Koput4, Beata Zelazowska- Rutkowska4, Jolanta Tobolczyk11Medical University in Bialystok, Poland, 2Department of Endocrinology. IHC., Poland, 3Dep. of Nuclear Medicine, Poland, 4Dep. of Ped. Laboratory Diagnostic. MU in Bialystok, Poland, 5Dep. of Children's Allergology. MU in Bialystok, Poland

Thyroid

P157

Bronchiectasis as a false-positive on Iodine-131 scintigraphy in thyroid papillary carcinoma- three case reports

Anabela Martins1 , Francisco Rosário1, António Garrão1, Pedro Quaresma2, Teresa Ferreira2, Rita Santos1, Maria Bugalho1, Valeriano Leite11Portuguese Institute of Cancer, Endocrinology, Portugal, 2Portuguese Institute of Cancer, Nuclear Medicine, Portugal

Thyroid

P158

Combined doxorubicin and hyperfracionated radiation therapy of anaplastic thyroid carcinoma- case report

Anabela Martins1 , Francisco Rosário1, Candida Trindade2, Rita Santos1, Maria Bugalho1, Valeriano Leite11Portuguese Institute of Cancer, Endocrinology, Portugal, 2Portuguese Institute of Cancer, Radiotherapy, Portugal

Thyroid

P159

THREE CASES WITH THYROID LYMPHOMA

Banu Aktas Yilmaz1 , Erdal Kan1, Fusun Balos Toruner1, Ayhan Karakoc1, Mustafa Benekli1, Nuri Cakir1, Suleyman Buyukberber1, Metin Arslan11Gazi Univercity Medical faculty, Turkey

Thyroid

P160

Autoimmune thyroid disease functional evolution: the role of thyroid volume.

Pierluigi De Remigis1 , Gaetana Parisi2, Teresa Consiglio1, Elisabetta Ciccarone2, Alessandra De Remigis3, Luigi Vianale1, Gaetano Frajese31Endocrine Unit-General Hospital, Italy, 2Endocrine Unit-General Hospital, Italy, 3Endocrine Clinic- University-Tor Vergata, Italy

Thyroid

P161

Predictors of incidental parathyroidectomy during thyroid surgery

Nikolaos Michalopoulos1 , Leonidas Alevizos1, Haridimos Markogiannakis1, Nikolaos Memos1, Aggelos Giannopoulos1, Sofia Malachtari1, Panagiotis Kekis1, Andreas Manouras11Department of Endocrine Surgery, 1st Department of Propaedeutic Surgery, Hippokrateion Hospital, Athens Medical School, University of Athens, Greece

Thyroid

P162

Thyroid surgery with the new harmonic scalpel: a prospective randomized study

Leonidas Alevizos1 , Nikolaos Michalopoulos1, Haridimos Markogiannakis1, Nikolaos Memos1, Dimitrios Tsamis1, Dimitrios Linardoutsos1, Panagiotis Kekis1, Andreas Manouras11Department of Endocrine Surgery, 1st Department of Propaedeutic Surgery, Hippokrateion Hospital, Athens Medical School, University of Athens, Greece

Thyroid

P163

Hashimoto’s Thyroiditis - the Value of Antithyreoperoxidase Antibodies Measurement

Dan Peretianu1 , Mara Carsote2, Ramona Samoila3, Cristina Ene3, Florin Alexiu3, Catalina Poiana2,31SCM Povernei, Romania, 2Carol Davila University of Medicine and Pharmacy, Romania, 3CI Parhon National Institute of Endocrinology, Romania

Thyroid

P164

PROPYLTHIOURACIL-INDUCED ANTI-NEUTROPHIL CYTOPLASMIC ANTIBODIES POSITIVE VASCULITIS

Marta Alves1 , Celestino Neves1, Ângela Magalhães1, Ana Varela1, Fernanda Guerra1, Lídia Pereira-Monteiro1, Davide Carvalho1, Paulo Morais2, Ana Calistru2, Teresa Braudier2, A. Mota2, J.A. Capela3, P.S. Couto3, R. Ramalho4, J.P. Ramos4, C. Guimarães4, J.L. Delgado1, J.L. Medina11Endocrinology department, S. João Hospital, Faculty of Medicine, University of Porto, Portugal, 2Dermatology department, S. João Hospital, Faculty of Medicine, University of Porto, Portugal, 3Surgery department, S. João Hospital, Faculty of Medicine, University of Porto, Portugal, 4Immunology department, S. João Hospital, Faculty of Medicine, University of Porto, Portugal

Thyroid

P165

New Clinical Feature in Hypothyroidism: Paroxysmal Supraventricular Tachycardia − Case Report

Cristina Olarescu1 , Cristina Ghervan1, Georgeta Hazi1, Ileana Duncea11University of Medicine and Pharmacy “Iuliu Hatieganu”, Romania

Thyroid

P166

Frequency of Subclinical Hypothyroidism (SH) and Autoimmune Thyroiditis (AT) in pregnancy.

Hernando Vargas Uricoechea1Cauca University, Colombia

Thyroid

P167

Evaluation of thyroid disorders in patients with alopecia areata

Pouran Layegh1 , Parvin Layegh2, Narges Sadeghi1, Mohammad Khajedaluee11Qaem Hospital, Mashad University of Medical Sciences, Mashad,Iran, Iran, Islamic Republic of, 2Imam Reza Hospital, Mashad University of Medical Sciences, Iran, Islamic Republic of

Thyroid

P168

Unusual onset of subacute thyroiditis. Case report

Ioana Stoica1 , Alina Plesa1, Delia Gabriela Ciobanu1, Roxana Dinu1, Eusebie Zbranca1, Carmen Vulpoi11University of Medicine, Romania

Thyroid

P169

Frequency of thyroid function test abnormalities in an open population in Queretaro, Mexico.

Ma. Ludivina Robles Osorio 1 , Hebert Luis Hernandez Montiel1, Juan Carlos Solis Sainz1, Pablo Garcia Solis1, Ernesto Francisco Sabath Silva1, Adrian Hernandez Lomeli1, Victor Eduardo Maya1, Nestor Ramirez1, David Gonzalez1, Alejandro Alcantara11Facultad de Medicina, Univerdidad Autonoma de Queretaro, Mexico

Thyroid

P170

Primary cavernous hemangioma of the thyroid gland

Nikolaos Michalopoulos1 , Artemisia Papadima1, Emmanuel Lagoudianakis1, Sotirios-Georgios Panoussopoulos1, Levon Toufektzian1, Leonidas Alevizos1, Haridimos Markogiannakis1, Andreas Manouras11Department of Endocrine Surgery, First Department of Propaedeutic Surgery, Hippokrateion Hospital, Athens Medical School, University of Athens, Greece

Thyroid

P171

Heart ischemic disease patients with mild thyroid failure.

A Volkova1 , E Grineva1, E Krasilnikova11Saint-Petersburg state medical university, Russian Federation

Endocrine Tumours and Neoplasia

P172

Manifestation of Hyperprolactinemia and IST managment by Bromocriptin and Cabergoline

Faiza Qari11KAUH, Saudi Arabia

Endocrine Tumours and Neoplasia

P173

Von-Hippel-Lindau disease: clinical report

Jacinta Santos1 , Isabel Paiva1, Mariana Martinho1, Alexandra Vieira1, Diniz Vieira2, Lurdes Cunha3, Fernando Martinho3, Manuela Carvalheiro11Endocrinology, Diabetes and Metabolism, University Hospital of Coimbra, EPE, Portugal, 2Medicine 2 DepartmentUniversity Hospital of Coimbra, EPE,, Portugal, 3Surgery 2 Department , University Hospital of Coimbra, EPE, Portugal

Endocrine Tumours and Neoplasia

P174

ASSESSMENT OF INTERFERON ALPHA-2a IN PHARMACEUTICAL FORMULATIONS BY LIQUID CHROMATOGRAPHY METHODS

Sérgio Luiz Dalmora1 , Lucélia Magalhães da Silva1, Estevan Sonego Zimmermann1, Aline Jacobi Dalla Lana1, Maximiliano da Silva Sangoi1, Felipe Bianchini D'Avila11Federal University of Santa Maria, Brazil

Endocrine Tumours and Neoplasia

P175

Pregnancy and childbirth in active acromegaly patient treated with long acting somatostatin analog

Olga Nechaeva1 , Julia Pokramovich1, Alexander Dreval11Moscow Regional Research Clinical Institute, Russian Federation

Endocrine Tumours and Neoplasia

P176

ECTOPIC GROWTH HORMONE-RELEASING HORMONE SECRETION BY A NEUROENDOCRINE TUMOR CAUSING ACROMEGALY: LONG-TERM FOLLOW-UP RESULTS

Nese Colak Ozbey1 , Yersu Kapran2, Alp Bozbora3, Yesim Erbil3, Cemil Tascioglu4, Silvia L. Asa51Istanbul University, Istanbul Medical Faculty, Department of Medicine, Division of Endocrinology, Turkey, 2Istanbul University, Istanbul Medical Faculty, Department of Pathology, Turkey, 3Istanbul University, Istanbul Medical Faculty, Department of Surgery, Turkey, 4Istanbul University, Istanbul Medical Faculty, Department of Medicine, Turkey, 5University Health Network, Department of Pathology, Canada

Endocrine Tumours and Neoplasia

P177

Misleading, difficult and lucky path towards a diagnosis in a Medullary Thyroid Carcinoma case.

Gaetana Parisi1 , Pierluigi De Remigis2, Luigi Vianale2, Elisabetta Ciccarone11Endocrine Unit-General Hospital, Italy, 2Endocrine Unit-General Hospital, Italy

Endocrine Tumours and Neoplasia

P178

Predictive value of interleukin-10 promoter genotypes and haplotypes in determining the susceptibility to nephropathy in type 2 diabetes patients

Nabil Mtiraoui1 , Intissar Ezzidi1, Molka Chieb2, Maha Kacem2, Touhami Mahjoub1, Wassim Y Almawi31Research Unit of Biology and Genetics of Cancer and Haematological and Autoimmune diseases, Faculty of Pharmacy of Monastir, Monastir, Monastir University, Tunisia, 2Nephrology and Internal Medicine Service, EPS F. Bourguiba of Monastir, Tunisia, 3Department of Medical Biochemistry,College of Medicine and Medical Sciences, Arabian Gulf University, Bahrain

Endocrine Tumours and Neoplasia

P179

AIP immunostaining is increased with lanreotide therapy in individuals with acromegaly and predicts changes in IGF-1 levels in female patients.

Harvinder Chahal1 , Olaf Ansorge2, Niki Karavitaki3, Eivind Carlsen1, John Wass3, Ashley Grossman1, Márta Korbonits11Centre for Endocrinology, Barts and the London School of Medicine, United Kingdom, 2Department of Neuropathology, John Radcliffe Hospital, United Kingdom, 3Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, United Kingdom

Endocrine Tumours and Neoplasia

P180

PAPILLARY THYROID CARCINOMA ASSOCIATED WITH THYROID AUTOIMMUNITY: CLINICAL AND MOLECULAR CHARACTERIZATION

Marina Muzza1,2 , Carla Colombo1,2, Michela Perrino1,2, Stefania Rossi3, Valentina Cirello1,2, Paolo Beck-Peccoz1,2, Laura Fugazzola1,21Department of Medical Sciences, University of Milan, Italy, 2Endocrine-Diabetological Unit, Fondazione Policlinico IRCCS, Italy, 3Pathology Unit, Department of Medicine, Surgery and Dentistry, University of Milan, Ospedale S. Paolo, Italy

Endocrine Tumours and Neoplasia

P181

Steroidogenic factor 1 - a valuable diagnostic and prognostic tool in patients with adrenocortical carcinoma

Silviu Sbiera1 , Sebastian Schmull1, Hans-Ullrich Voelker2, Luitgard Kraus1, Felix Beuschlein3, Holger Willenberg4, Stefanie Hahner1, Bruno Allolio1, Martin Fassnacht11Department of Medicine I, Endocrine and Diabetes Unit, University Hospital Würzburg, Germany, 2Department of Pathology, University Hospital Würzburg, Germany, 3Department of Endocrinology, University of Munich, Germany, 4Department of Endocrinology, University of Düsseldorf, Germany

Endocrine Tumours and Neoplasia

P182

Endocrine gland-derived vascular endothelial growth factor (EG-VEGF) and its receptors in adrenocortical carcinoma

Silviu Sbiera1 , Dorothee Kuehner1, Sebastian Wortmann1, Patrick Adam2, Hans- Ullrich Voelker2, Luitgard Kraus1, Melanie Beyer1, Markus Quinkler3, Holger Willenberg4, Dirk Weismann1, Stefanie Hahner1, Bruno Allolio1, Martin Fassnacht11Department of Medicine I, Endocrine and Diabetes Unit, University Hospital Würzburg, Germany, 2Department of Pathology, University Hospital Würzburg, Germany, 3Department of Endocrinology, Charite University Berlin, Germany, 4Department of Endocrinology, University of Düsseldorf, Germany

Endocrine Tumours and Neoplasia

P183

DIFFERENTIAL EXPRESSION OF MICRORNAS IN HUMAN PARATHYROID CARCINOMAS COMPARED WITH NORMAL PARATHYROID TISSUE

Sabrina Corbetta1 , Valentina Vaira2, Vito Guarnieri3, Alfredo Scillitani4, Cristina Eller-Vainicher5, Leonardo Vicentini6, Jacopo Chiodini5, Michele Bisceglia7, Paolo Beck-Peccoz5, Silvano Bosari2, Anna Spada51Endocrinology and Diabetology Unit, Dept. Medical-Surgical Sciences, University of Milan, IRCCS Policlinico S.Donato, Italy, 2Pathology Unit, Dept. of Medicine, Surgery and Dentistry, University of Milan, A.O.S. Paolo, and IRCCS Fondazione Ospedale Maggiore Policlinico, Mangiagalli and Regina Elena, Italy, 3Unit of Medical Genetics, IRCCS Hospital Casa Sollievo della Sofferenza, Italy, 4Unit of Endocrinology, IRCCS Hospital Casa Sollievo della Sofferenza, Italy, 5Endocrine Unit, Dept. Medical Sciences, University of Milan, IRCCS Fondazione Ospedale Maggiore Policlinico, Regina Elena, Mangiagalli, Italy, 6Endocrine Surgery, IRCCS Fondazione Ospedale Maggiore Policlinico, Regina Elena, Mangiagalli, Italy, 7Unit of Pathology, IRCCS Hospital Casa Sollievo della Sofferenza, Italy

Endocrine Tumours and Neoplasia

P184

Recombinant human thyrotropin in follow-up of patients with differentiated thyroid cancer

Jan Podoba11St.Elizabeth Cancer Institute, Slovakia

Endocrine Tumours and Neoplasia

P185

ESTRADIOL INFLUENCES SOMATOSTATIN RECEPTOR EXPRESSION AND POTENTIATES THE EFFECTS OF SOM230 ON PROSTATE CELLS

Valentina Rossi1, Giuseppe Bellastella1, Daniela Visconti1, Ciro Abbondanza2, Luigi Maione1, Antonio Bellastella1, Antonio Agostino Sinisi11Endocrinology, Internal Medicine and Surgery Dpt, Second University of Napoli, Italy, 2General Pathology Dpt, Second University of Napoli, Italy

Endocrine Tumours and Neoplasia

P186

mTOR inhibition influences cell viability of medullary thyroid carcinoma primary cultures

Carlo Filieri1, Mariella Minoia1, Federico Tagliati1, Daniela Molè1, Mattia Buratto1, Angelo Margutti1, Ettore degli Uberti1, Maria Chiara Zatelli11Dept of Biomedical Sciences and Advanced Therapies, Section of Endocrinology, University of Ferrara, Italy

Endocrine Tumours and Neoplasia

P187

Presence and potential pathophysiological relevance of GOAT, the ghrelin O- acylation enzyme, in human pituitary tumors.

Ana Quintero1, Antonio J. Martinez-Fuentes1, Carlos Dieguez2, Pedro Benito-Lopez1, Alfonso Leal3, Susan Webb4, Maria M. Malagon1, Raul M. Luque1, Justo P. Castano11University of Cordoba & CIBERobn, Spain, 2Univ of Santiago de Compostela, Spain, 3IBIS-Hosp. Virgen del Rocio, Spain, 4Hosp Sant Pau, UAB & CIBERER, Spain

Endocrine Tumours and Neoplasia

P188

Efficacy of repeat surgery in patients with recurrent adrenocortical cancer (ACC).

Fulvia Daffara1 , Silvia De Francia3, Arianna Ardito1, Barbara Zaggia1, Cristian Fiori4, Alberto Angeli1, Roberto Scarpa4, Francesco Porpiglia4, Paola Perotti2, Alfredo Berruti2, Massimo Terzolo11Medicina Interna, Dipartimento di Scienze Cliniche e Biologiche, Università di Torino, Italy., Italy, 2Oncologia, Dipartimento di Scienze Cliniche e Biologiche, Università di Torino, Italy., Italy, 3Farmacologia, Dipartimento di Scienze Cliniche e Biologiche, Università di Torino, Italy., Italy, 4Urologia, Dipartimento di Scienze Cliniche e Biologiche, Università di Torino, Italy., Italy

Endocrine Tumours and Neoplasia

P189

Tumor/liver SUV ratio

David Taïeb1 , Laurent Tessonnier1, Frederic Sebag1, Isabelle Morange1, Catherine De Micco1, Bernard Conte-Devolx1, Jean-François Henry1, Olivier Mundler11CHU Timone, France

Endocrine Tumours and Neoplasia

P190

Serum Chromogranin A assay in the biological diagnosis of pheochromocytomas and/or paragangliomas : results in 146 patients

Michele d'Herbomez1 , Catherine Bauters2, Philippe Caron3, Christine Do Cao2, Pascal Pigny4, Emmanuelle Leteurtre5, Bruno Carnaille6, Jean-Louis Wémeau21Department of nuclear Medicine, France, 2Clinic of Endocrinology, France, 3Clinic of Endocrinology, France, 4Department of Biochemistry, France, 5Department of Pathology, France, 6department of endocrine Surgery, France

Endocrine Tumours and Neoplasia

P191

CLINICAL FEATURES AND OUTCOME OF THYROID LYMPHOMA : THE AUVERGNE REGISTRY

Beatrice ROCHE1, Caroline SOLMON1, Elena ROBU1,2, Francoise DESBIEZ1, Philippe THIEBLOT1,2, Igor TAUVERON1,21CHU Endocrinology, France, 2UFR Medecine Université d'Auvergne, France

Endocrine Tumours and Neoplasia

P192

“The comparison of serum endostatin levels between patients with metastatic and non-metastatic well differentiated thyroid cancer”

Joanna Klubo-Gwiezdzinska1, Junik Roman1, Kopczynska Ewa21Department of Endocrinology and Diabetology, Nicolaus Copernicus University in Torun, Collegium Medicum in Bydgoszcz, Poland, 2Department of Biochemistry, Nicolaus Copernicus Yniversity in Torun, Collegium Medicum in Bydgoszcz, Poland

Endocrine Tumours and Neoplasia

P193

EFFECTIVENESS AND SAFETY OF COMBINED THERAPY WITH LOW DOSE KETOCONAZOLE AND CABERGOLINE IN PATIENTS WITH CUSHING’S DISEASE PARTIALLY RESPONSIVE TO MONOTHERAPY WITH CABERGOLINE.

Rosario Pivonello1 , Monica De Leo1, Maria Cristina De Martino1, Alessia Cozzolino1, Renata S Auriemma1, Mariano Galdiero1, Gaetano Lombardi1, Annamaria Colao11Department of Molecular and Clinical Endocrinology and Oncology; Federico II University, Italy

Endocrine Tumours and Neoplasia

P194

Impact of surgery on clinical outcome in patients with recurrence of adrenocortical carcinoma

Ilknur Erdogan1 , Stefanie Hahner1, Sarah Johanssen1, Wiebke Fenske1, Marcus Quinkler2, Holger S. Willenberg3, Felix Beuschlein4, David Brix5, Bruno Allolio1, Martin Fassnacht11University Hospital, Dept. of Medicine, Germany, 2Charite University, Campus Mitte, Dept. of Medicine, Germany, 3University Hospital, Dept. of Endocrinology, Diabetes, Rheumatology, Germany, 4University Hospital, Dept. of Medicine - Innenstadtklinikum, Germany, 5University Hospital, Dept. of Urology, Germany

Endocrine Tumours and Neoplasia

P195

MICROALBUMINURIA AND INSULIN RESISTANCE IN NONDIABETIC ACROMEGALIC PATIENTS

Ayse Serap Yalin1 , Seda Sancak1, Oguzhan Deyneli1, Mutlu Gunes1, Dilek Gogas Yavuz1, Nefise Sema Akalin11Marmara University, School of Medicine, Section of Endocrinology and Metabolism, Turkey

Endocrine Tumours and Neoplasia

P196

SAFETY OF LONG-TERM COMBINED THERAPY WITH SOMATOSTATIN ANALOGUES (SA) AND CABERGOLINE (CAB) ON CARDIAC VALVE IN ACROMEGALY: AN ECHOCARDIOGRAPHY STUDY.

Renata Simona Auriemma, Maurizio Galderisi2, Mariano Galdiero1, Ludovica Francesca Stella Grasso1, Maria Cristina De Martino1, Monica De Leo1, Annamaria Colao1, Rosario Pivonello11Dept of Clinical and Molecular Endocrinology and Oncology, University “Federico II”,, Italy, 2Dept of Clinical and Experimental Medicine, University “Federico II”, Italy

Endocrine Tumours and Neoplasia

P197

INCIDENCE OF BENIGN AND MALIGNANT NEOPLASMS IN ACROMEGALIC PATIENTS AT A SINGLE INSTITUTION.

Agata Baldys-Waligorska, Filip Golkowski1, Anna Krzentowska1, Grzegorz Sokolowski1, Alicja Hubalewska-Dydejczyk11Department of Endocrinology, Collegium Medicum, Jagiellonian University, Poland

Endocrine Tumours and Neoplasia

P198

Gastric Neuroendocrine Tumors –New Diagnostic and Therapeutic Approach

Alicja Hubalewska-Dydejczyk1, Aleksandra Gilis- Januszewska1, Anna Sowa-Staszczak1, Dorota Pach1, Malgorzata Trofimiuk1, Monika Tomaszczuk1, Jan Kulig21Chair and Dept. of Endocrinology, Jagiellonian University, Poland, 2Gastrointestinal and General Surgery Department, Medical College, Jagiellonian University, Poland

Endocrine Tumours and Neoplasia

P199

The German NET-Registry: An Audit on the Diagnosis and Therapy of Neuroendocrine Tumours

Ursula Plöckinger1 , Günther Klöppel2, Rüdiger Lohmann31Charité- Universitätsmedizin Berlin, Germany, 2Universitätsklinikum Schleswig- Holstein, Germany, 3Lohmann&Birkner Health Care Consulting, Germany

Endocrine Tumours and Neoplasia

P200

Adrenocortical carcinoma: results of surgical treatment and clinico-morphological prognostic factors

Denis Pirogov1 , Timur Britvin1, Galina Polyakova1, Oleg Bogatyrev11Moscow Regional M.F. Vladimirsky Clinical Research Institute, Russian Federation

Endocrine Tumours and Neoplasia

P201

Parathyroid cancer

Irina Kotova1 , Timur Britvin1, Mikhail Beloshitsky1, Arian Kalinin11Moscow Regional M.F. Vladimirsky Clinical Research Institute, Russian Federation

Endocrine Tumours and Neoplasia

P202

A National Survey of Neuroendocrine Lung Tumors

Bojana Popovic1 , Tatjana Isailovic1, Ivana Bozic1, Djuro Macut1, Sanja Ognjanovic1, Milan Petakov1, Valentina Elezovic1, Svetozar Damjanovic11Institute of Endocrinology, Diabetes and Metabolic Diseases, Serbia

Endocrine Tumours and Neoplasia

P203

Efficacy and safety of 90Y-DOTATATE therapy in neuroendocrine tumours (NETs).

Anna Sowa-Staszczak1 , Alicja Hubalewska-Dydejczyk1, Jolanta Kunikowska2, Leszek Królicki2, Renata Mikolajczak3, Dariusz Pawlak3, Aleksandra Gilis-Januszewska1, Malgorzata Trofimiuk1, Agnieszka Stefanska11Nuclear Medicine Unit, Endocrinology Department, Jagiellonian University, Medical College, Poland, 2Nuclear Medicine Department, Medical Academy, Poland, 3Research and Development Department, IAE Radioisotope Centre POLATOM, Poland

Endocrine Tumours and Neoplasia

P204

The variability of clinical presentation of Multiple Endocrine Neoplasia syndrome type1 as the reason of the underestimated diagnosis.

Elwira Elwira1 , Alicja Hubalewska-Dydejczyk1, Dorota Pach1, Sylwia Kuniarzz1, Marta Tracz11Chair and Department of Endocrinology, Collegium Medicum, Jagiellonian University, Poland

Endocrine Tumours and Neoplasia

P205

Acromegaly in the Swedish Pituitary Register - Background Data and up to 10 years Follow-up

Britt Edén Engström1 , Margareta Bramnert2, Bertil Ekman3, Charlotte Höybye4, Anders Karlsson1, Cecilia Mattsson5, Thord Rosén6, Stig Valdemarsson7, Sigbritt Werner81Uppsala University Hospital, Sweden, 2Malmö University Hospital, Sweden, 3Linköping University Hospital, Sweden, 4Karolinska University Hospital, Sweden, 5Umeå University Hospital, Sweden, 6Sahlgrenska University Hospital, Sweden, 7Lund University Hospital, Sweden, 8Karolinska University Hospital, Sweden

Endocrine Tumours and Neoplasia

P206

PERCUTANEOUS LASER ABLATION FOR PALLIATIVE TREATMENT OF NEUROENDOCRINE LIVER METASTASES

Silvia Nasoni2, Claudio Maria Pacella3, Antonio Bianchini3, Giancarlo Bizzarri3, Zaccaria Rossi3, Enrico Papini2, Irene Misischi2, Franco Grimaldi11Endocrinology Unit, University Hospital, Italy, 2Endocrine & Metabolic Diseases, Regina Apostolorum Hospital, Italy, 3Imaging and Interventional Radiology, Regina Apostolorum Hospital, Italy

Endocrine Tumours and Neoplasia

P207

The colonic polyps in the patients wich acromegaly

Alexandr Dreval1 , Tamara Kamynina1, Julia Pokramovich1, Olga Nechaeva1, Sergey Tereschenko1, Victoria Banina11Moscow Regional Research Clinical Institute, Russian Federation

Endocrine Tumours and Neoplasia

P208

Laboratory diagnosis of gastrinoma remains dfficult

Joy Ardill1,2 , Lee Armstrong1, David McCance1, Brian Johnston11Royal Victoria Hospital, United Kingdom, 2Queen's University Belfast, United Kingdom

Endocrine Tumours and Neoplasia

P209

R171Q MEN1 POLYMORPHISM IN PATIENTS PRESENTING WITH HYPERPARATHYROIDISM

Maria Chiara Zatelli1 , Carlo Filieri1, Federico Tagliati1, Maria Rosaria Ambrosio1, Ettore degli Uberti11Section of Endocrinology, Dept. of Biomedical Sciences and Advanced therapies, University of Ferrara, Italy

Endocrine Tumours and Neoplasia

P210

Recurrence in patients with pituitary nonfunctioning adenoma

Grazia De Paola1, Roxana Elena Buzoianu1, Marta Bondanelli1, Giorgio Trasforini1, Maria Chiara Zatelli1, Marcello Laparelli2, Luigi Cavazzini3, Maria Rosaria Ambrosio1, Ettore degli Uberti11Dept of Biomedical Sciences and Advanced Therapies, Section of Endocrinology, University of Ferrara, Italy, 2Neurosurgery Unit, Italy, 3Dept of Experimental Medicine and Diagnostics, Section of Pathology, Italy

Endocrine Tumours and Neoplasia

P211

Clinical features and genetic testing in patients with Multiple Endocrine Neoplasia syndrome type 2.

Elwira Przybylik-Mazurek, Alicja Hubalewska-Dydejczyk11, Dorota Pach1, Sylwia Kuzniarz1, Barbara Jarzab2, Elzbieta Gubala2, Agnieszka Pawlaczek2, Malgorzata Oczko - Wojciechowska21Chair and Department of Endocrinology Collegium Medicum Jagiellonian University in Kraków, Poland, 2Department of Nuclear Medicine and Endocrine Oncology, Maria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Poland

Endocrine Tumours and Neoplasia

P212

Pancreatic neuroendocrine tumors: national survey

Tatjana Isailovic1 , Bojana Popovic1, Milan Petakov1, Sanja Ognjanovic1, Djuro Macut1, Ivana Bozic1, Valentina Elezovic1, Svetozar Da11Institute of endocrinology, University Clinical Centre, Serbia

Endocrine Tumours and Neoplasia

P213

Image-guided radioiodine therapy of HCC following AFP-promoter targeted in vivo sodium iodide symporter (NIS) gene transfer

Katrin Klutz1 , Michael J Willhauck1, Nathalie Wunderlich1, Christian Zach1, Reingard Senekowitsch-Schmidtke2, Martina Anton2, Burkhard Göke1, Christine Spitzweg11Ludwig- Maximilians-University, Germany, 2Technische Universität, Germany

Endocrine Tumours and Neoplasia

P214

The retrospective analysis of the pheochromocytoma diagnostic procedures in patients after laparoscopic adrenalectomy

Alicja Hubalewska-Dydejczyk, Andrzej Budzynski2, Monika Buziak-Bereza1, Dorota Pach1, Ewa Stochmal1, Malgorzata Trofimiuk1, Elwira Przybylik-Mazurek1, Robert Chrzan3, Danuta Karcz2, Andrzej Urbanik11Chair and Department of Endocrinology, Medical College, Jagiellonian University, Poland, 2Endoscopic Surgery Department, Medical College, Jagiellonian University, Poland, 3Chair of Radiology, Medical College, Jagiellonian University, Poland

Endocrine Tumours and Neoplasia

P215

Neuroendocrine disorders of patients with pituitary tumours

Said Ismailov1 , Kozim Makhkamov1, Michael Powell1, Ashley Grossman1, Zamira Khalimova1, Yulduz Urmanova11Institute of Endocrinology, Uzbekistan

Endocrine Tumours and Neoplasia

P216

Insulinomas – Experience of Coimbra’s University Hospital, Endocrinology Department

Jacinta Santos1 , Isabel Paiva1, Mariana Martinho1, Alexandra Vieira1, Manuela Carvalheiro11Endocrinology, Diabetes and Metabolismo Dept, University Hospital of Coimbra, EPE, Portugal

Endocrine Tumours and Neoplasia

P217

The Ectopic Adrenocorticotropic Hormone Syndrome in Carcinoid Tumors (case report)

Nino Gabidzashvili2 , Olga Vinogradskaya1, Polina Zykova1, Vyatcheslav Pronin11Sechenov Moscow Medical Academy, Russian Federation, 2Academician N. Kipshidze Central University Clinic, Georgia

Endocrine Tumours and Neoplasia

P218

Growth Hormone Deficiency Problems in Adult Patients with Pituitary Adenomas

Yulduz Urmanova1 , Mukhlisa Shakirova11Institute of Endocrinology, Uzbekistan

Endocrine Tumours and Neoplasia

P219

Parathyroid surgery a paradigm shifts from inpatient to a day case surgery

Apurva Sinha1 , Afaq Siddiqui1, Raj Siddhan1, Makam Kishore1, V Parkinathan11George Eliot Hospital NHS Trust, United Kingdom

Endocrine Tumours and Neoplasia

P220

Oktreotid-depot therapy of acromegaly with long action somatostatin analogue

Julia Pokramovich1, Alexandr Dreval1, Olga Nechaeva1, Viacheslav Pronin1,2, Dmitry Koloda1,2, Evgeny Gitel1,21Moscow Regional Research Clinical Institute of M.F. Vladimirsky, Russian Federation, 2Moscow Medical Academy of I.M. Sechenov, Russian Federation

Endocrine Tumours and Neoplasia

P221

Severe elevation of testosterone serum levels as unique finding in occult Sertoli-Leydig ovarian cell tumors.

Rosa Maria Paragliola1, Maria Pia Ricciato1, Francesca Gallo1, Annapina De Rosa1, Paola Senes1, Carlo Antonio Rota1, Alfredo Pontecorvi1, Salvatore Maria Corsello11Department of Endocrinology, Catholic University School of Medicine, Italy

Endocrine Tumours and Neoplasia

P222

Treatment of active acromegaly with the somatostatin analogue lanreotide SR

Myroslava Mykytuyk1 , Oksana Khyzhnyak1, Yuriy Karachentsev11Institute for Endocrine Pathology Problems, Ukraine

Endocrine Tumours and Neoplasia

P223

Should we offer combination scan in all patients with parathyroid disease: A district general hospital experience.

Apurva Sinha1, Afaq Siddiqui1, Raj Siddhan1, Makam Kishore1, V Parkinathan11Geoge Eliot hospital NHS Trust, United Kingdom

Endocrine Tumours and Neoplasia

P224

Lanreotide effects on glucose metabolism in evolutive acromegaly in remission during chemotherapy

Simona Galoiu1,2 , Mariana Purice2, Dan Hortopan2, Anda Dumitrascu2, Mihail Coculescu1,21"Carol Davila" University of Medicine and Pharmacy, Romania, 2Institute of Endocrinology, Romania

Bone/Calcium

P225

THE STUDY OF BONE TURNOVER BIOCHEMICAL MARKERS IN DELAYED PUBERTY

Iulia Bistriceanu1 , Aurora Covei4, Elena Neacsu2, Ionut Vasile3, Magda Elvira Preda1, Marian Bistriceanu21Emergency Hospital-Department of Endocrinology, Romania, 2Universitary Endocrinology Hospital Dr. C.I.Parhon, Romania, 3University of Medicine and Pharmacy, Romania, 4Filantropia Hospital- Department of Endocrinology,, Romania

Bone/Calcium

P226

The new biology of pituitary natriuretic peptides: novel signalling from guanylyl cyclase-B (GC-B) receptors Bucuraş Dana1,2, Poenaru D.V.1,3, Golea O.4 1 University of medicine and Pharmacy „Victor Babeş” Timişoara 2 ObGZN Clinic nr.I, „Dumitru Popescu” Hospital,Timişoara 3 Clinic for otrhopedy and traumatology II, County Hospital, Timişoara 4 Haemodialysis and transplantation Clinic, Countz Hopsital, Timişoara

Bucuras Dana1,2 , POENARU DAN1,3, Golea Ovidiu41University of medicina and Pharmacy, Romania, 2ObGYN Clinic I, Romania, 3Otropedy adn Traumatology Clinic II, Romania, 4Haemodialysis and transplantation Clinic, Romania

Bone/Calcium

P227

Experience with cinacalcet in Primary Hyperparathyroidism: Results from the Swiss Primary Hyperparathyroidism Cohort Study

Christian Meier1 , Andrea Trombetti2, Christoph Henzen3, Andreas Rohrer4, F Hermann2, Michael Braendle5, Emanuel Christ6, Rene Rizzoli2, Marius Kraenzlin11Division of Endocrinology and Diabetology, University Hospital, Switzerland, 2Bone Disease Service, University Hospital, Switzerland, 3Department of Internal Medicine, Kantonsspital, Switzerland, 4Endocrine Clinic, Switzerland, 5Division of Endocrinology and Diabetes, Kantonsspital, Switzerland, 6Department of Endocrinology and Diabetes, University Hospital, Switzerland

Bone/Calcium

P228

Use of Cinacalcet in Patients with Intractable Primary Hyperparathyroidism (PHPT): A UK Budget Impact Analysis

Monique Martin1 , Sean Robbins2, Z John Lu31Amgen, Switzerland, 2Amgen, United States, 3Innovus, United Kingdom

Bone/Calcium

P229

SWISS PRIMARY HYPERPARATHYROIDISM COHORT STUDY

Andrea Trombetti1 , Christian Meier2, Marius E Kraenzlin2, François R Herrmann1, Christoph H Henzen3, Emmanuel R Christ5, Michael Brändle4, René Rizzoli11Bone Disease Service, University Hospital of Geneva, Switzerland, 2Division of Endocrinology, Diabetes, and Clinical Nutrition, University Hospital of Basel, Switzerland, 3Medizinische Klinik, Kantonsspital Luzern, Switzerland, 4Division of Endocrinology and Diabetes, Kantonsspital St. Gallen, Switzerland, 5Department of Endocrinology and Diabetology, University Hospital of Bern, Switzerland

Bone/Calcium

P230

Bone mineral density among patients with primary hyperparathyroidism with or without diabetes

Francesco Tassone1 , Laura Gianotti1, Micaela Pellegrino1, Claudia Baffoni1, Michela Ghio1, Ignazio Emmolo1, Giorgio Borretta11Endocrinology and Metabolism, Italy

Bone/Calcium

P231

Bone and mineral metabolism before and after Kidney-pancreas transplantation in patients with type 1 diabetes

Daniel Vaz1 , L. Martins1, L. Dias1, C. Henriques1, F. Oliveira1, R. Seca1, A. Lhamas1, S. Esteves1, A. Ribeiro1, R. Almeida1, M. Teixeira1, J. Dores11Centro Hospitalar do Porto, Portugal

Bone/Calcium

P232

Clinical and molecular characterization of Spanish patients with pseudohypoparathyroidism

Maria Dolores Moure1 , Eduardo Fernandez-Rebollo1, Sonia Gaztambide1,2, Gustavo Perez- Nanclares1, Luis Castano1,2, Guiomar Perez de Nanclares1,2, Spanish PHP group11Endocrinology and Diabetes research Group, Hospital de Cruces, Spain, 2CIBERER, Spain

Bone/Calcium

P233

IS PARATHYROID FUNCTION ABNORMAL IN ACTIVE ACROMEGALY

CONSTANTINOS TZIORAS1 , GEORGE IOANNIDIS1, ANDROMAXI VRIONIDOU11RED CROSS HOSPITAL, Greece

Bone/Calcium

P234

The circulating concentration of adiponectin in post-menopausal women with and without osteoporosis and its association with body mass index and biochemical markers of bone metabolism.

R Sodi 1,2 , MJ Hazell3, BH Durham2, C Rees1, LR Ranganath1,2, WD Fraser1,21Department of Clinical Biochemistry & Metabolic Medicine, Royal Liverpool & Broadgreen University Hospital, United Kingdom, 2Unit of Clinical Chemistry, School of Clinical Sciences, The University of Liverpool, United Kingdom, 3Protein and Peptides Laboratory, Oxford Brookes University, United Kingdom

Bone/Calcium

P235

GLUCOSE TOLERANCE, INSULIN SECRETION AND INSULIN SENSITIVITY BEFORE AND AFTER RADICAL TREATMENT OF PRIMARY HYPERPARATHYROIDISM

Dragan Micic1 , Goran Cvijovic1, Aleksandra Kendereski1, Mirjana Sumarac- Dumanovic1, Svetlana Zoric1, Snezana Polovina2, Danica Stamenkovic-Pejkovic11Institute of endocrinology, diabetes and diseases of metabolism, Serbia, 2Department of endocrinology, Medical center Subotica, Serbia

Bone/Calcium

P236

BONE MINERAL DENSITY AND BONE TURNOVER MARKERS IN PATIENTS WITH SCHIZOPHRENIA TREATED WITH ATYPICAL ANTIPSYCHOTICS

Mirjana Doknic1 , Nadja Maric2, Dubravka Britvic2, Sandra Pekic1, Aleksandar Damjanovic2, Marina Djurovic1, Marko Stojanovic1, Miroslava Jasovic-Gasic2, Vera Popovic11Institute of Endocrinology, University Clinical Center, Serbia, 2Institute of Psychiatry, University Clinical Center, Serbia

Bone/Calcium

P237

Thin healthy women have a similar low bone mass as women with anorexia nervosa

Diego Fernández-García, Arántzazu Sebastian1, Jorge García-Aleman1, Jose Manuel García-Almeida1, Francisco Tinahones11Hospital Virgen de la Victoria, Spain

Bone/Calcium

P238

Evaluation of the association between bone turnover markers and OPG/sRANK-L levels in relation with the changes of thyroid function in women with thyroid cancer

Serpil Salman1 , Ferihan Aral1, Harika Boztepe1, Nese Colak1, Beyhan Omer2, Refik Tanakol1, Faruk Alagol1, Ayse Kabut- Uzum11Division of Endocrinology and Metabolism, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Turkey, 2Central Laboratory of Biochemistry, Istanbul Faculty of Medicine, Istanbul University, Turkey

Bone/Calcium

P239

The results of cinacalcet therapy in patients with severe or refractory hypercalcemia due to primary hyperparathyroidism.

Jolanta Krajewska1 , Ewa Paliczka-Cieslik1, Aleksandra Krawczyk1, Sylwia Szpak-Ulczok1, Barbara Michalik1, Kornelia Hasse-Lazar1, Beata Jurecka-Lubieniecka11MSC Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Poland

Bone/Calcium

P240

THE EFFECT OF SHORT TERM HUMAN CHORIONIC GONADOTROPIN TREATMENT ON THE IMPROVEMENT OF BONE MASS IN PATIENTS WITH HYPOGONADOTROPIC HYPOGONADISM

Erol Bolu1 , Alper Sonmez1, Mehmet Apikoglu2, Hasan Gurel2, Ozdes Emer3, Abdullah Taslipinar1, M. Ali Ozguven3, Mustafa Kutlu11Gulhane Military Medical School Department of Endocrinology and Metabolism, Turkey, 2Gulhane Military Medical School Department of Internal Medicine, Turkey, 3Gulhane Military Medical School Department of Nuclear Medicine, Turkey

Bone/Calcium

P241

Role of Vıtamın D Replacement on Serum FGF-23 Levels in Patients With Osteomalacia Due to Vitamin D Defficiency

Ayse Kubat Uzum1 , Aysegul Telci2, Harika Boztepe3, Nese Colak3, Faruk Alagol31Istanbul Research and Training Hospital, Department of Internal Medicine, Turkey, 2Istanbul University, Istanbul Faculty of Medicine,Department of Biochemistry, Turkey, 3Istanbul University, Istanbul Faculty of Medicine,Department of Internal Medicine, Division of Endocrinology and Metabolism, Turkey

Bone/Calcium

P242

Peculiar features of bone disease in thalassemia. Comparison with anorexia nervosa.

Agnese Cattaneo1 , Leila Danesi1, Massimo Scacchi1, Chaiara Carzaniga1, Silvia Vai2, Sergio Ortolani2, Maria Domenica Cappellini3, Francesco Cavagnini11Chair of Endocrinology, University of Milan, Ospedale San Luca IRCCS, Istituto Auxologico Italiano, Italy, 2Bone Metabolism Unit, Ospedale San Michele IRCCS, Istituto Auxologico Italiano, Italy, 3Department of Internal Medicine, University of Milan, Italy

Bone/Calcium

P243

The influence of other hormonal disturbances on the bone density and turnover in women with hyperprolactinemia of various origin

Marek Bolanowski1 , Beata Zadrozna-Sliwka1, Aleksandra Jawiarczyk1, Joanna Syrycka11Medical University, Poland

Bone/Calcium

P244

Effect of one year treatment with strontium ranelate on bone mineral density in women with established osteoporosis previously treated with teriparatide

Athanasios Anastasilakis1 , Stergios Polyzos2, Avraam Avramidis2, Athanasios Papatheodorou3, Evagellos Terpos31424 Military Hospital, Greece, 2Hippokration General Hospital, Greece, 3251 General Air Force Hospital, Greece

Bone/Calcium

P245

BODY COMPOSITION AND BONE MINERAL DENSITY IN HEMODIALYSIS PATIENTS

Zorica Rasic-Milutinovic, Gordana Perunicic-Pekovic2, Olivera Stojanovic3, Jelena Tica1, Vesna Popovic1, Marina Vujovic1, Zoran Gluvic11Dep.of endocrinology, University hospital Zemun/Belgrade, Serbia, 2Dep. of nephrology and hemodialysis, University hospital Zemun/Belgrade, Serbia, 33Institute for rehabilitation, Medical School Belgrade, Serbia

Bone/Calcium

P246

The Relationship between Serum TSH, free T4 and Bone Mineral Density in Pre- and Postmenopausal Women

Lahim Baqi1 , Pavel Langer2, Zdenko Killinger1, Zuzana Homerova1, Jana Kollerova1, Adriana Banarova1, Juraj Payer115th Department of Internal Medicine, Faculty Hospital Bratislava, Slovakia, 2Institute of Experimental Endocrinology, SAS, Slovakia

Bone/Calcium

P247

Changes in adipokines serum levels after anticatabolic drugs in postmenopausal osteoporosis.

Arántzazu Sebastian-Ochoa, Diego Fernández-García1, Rebeca Reyes-García2, Manuel Muñoz-Torres31Hospital Virgen de la Victoria, Spain, 2Hospital Rafael Mendez, Spain, 3Hospital Clínico San Cecilio, Spain

Bone/Calcium

P248

Influence of age, menopause and body composition on bone mineral density in non-obese healthy Romanian subjects

Carmen Georgescu1,2 , Ioana Ilie1,2, Cristian Brad2, Ioana Duncea3, Adrian Paul2, Ileana Duncea1,21Department of Endocrinology, University of Medicine and Pharmacy Cluj, Romania, 2Clinic of Endocrinology, Emergency County Hospital Cluj, Romania, 3Faculty of Dental Medicine, University of Medicine and Pharmacy Cluj, Romania

Bone/Calcium

P249

Bone mineral density, bone turnover, serum osteoprotegerin and soluble receptor activator of nuclear factor kβ ligand levels in patients with differentiated thyroid cancer

Sabriye Özkaya Kafesçiler1, Zeliha Hekimsoy1, Fatma Taneli1, Feray Aras1, Bilgin Özmen1, Feyzullah Güçlü11Celal Bayar University Medical Faculty, Turkey

Bone/Calcium

P250

Colecalciferol loading dose guideline for vitamin D deficient Adults

Lenneke van Groningen1 , Adriaan van Sorge1, Darryl Telting1, Astrid Giesen1, Hans de Boer11Rijnstate Hospital, Netherlands

Bone/Calcium

P251

The incidence of osteoporotic hip fracture in north west of IRAN

Akbar Aliasgarzadeha1 , Amir Bahrami1, Majid Ramazani1, Farzad Najafipoor1, Amin Moradi11Tabriz University (Medical Sciences), Iran, Islamic Republic of

Bone/Calcium

P252

Metabolic and cardiovascular risk in primary hyperparathyroidism.

Mara Dolcino1, Francesca Massaro1, Lara Vera1, Silvia Oddo1, Guido Rodriguez1, Diego Ferone1, Francesco Minuto1, Massimo Giusti11Dipartimento di Scienze Endocrinologiche e Mediche, University of Genova, Italy

Bone/Calcium

P253

VITAMIN D INADEQUACY IN PATIENTES WHO ARE SCREENED FOR OSTEOPOROSIS

Rebeca Reyes-García1 , Diego Fernández-García2, Arántzazu Sebastián-Ochoa2, Manuel Muñoz- Torres31Endocrinology Division. Rafael Mendez Hospital, Spain, 2Endocrinology Division. Virgen de la Victoria University Hospital, Spain, 3Endocrinology Division. San Cecilio University Hospital, Spain

Bone/Calcium

P254

RENAL FUNCTION BEFORE AND AFTER RADICAL TREATMENT OF PRIMARY HYPERPARATHYROIDISM

Goran Cvijovic1 , Dragan Micic1, Aleksandra Kendereski1, Svetlana Zoric1, Mirjana Sumarac-Dumanovic1, Danica Stamenkovic- Pejkovic11Institute of Endocrinology, Diabetes and Diseases of metabolism, Serbia

Bone/Calcium

P255

PREOPERATIVE PARATHYROID HORMONE LEVELS ARE CORRELATED WITH PARATHYROID ADENOMA VOLUME, BONE MINERAL DENSITY BUT NOT SERUM CALCIUM LEVELS

Sinem KIYICI1 , Soner CANDER1, Ozen OZ GUL1, Deniz SIGIRLI2, Oguz Kaan UNAL1, Ozlem SARAYDAROGLU3, Canan ERSOY1, Erdinc ERTURK1, Ercan TUNCEL1, Sazi IMAMOGLU11Uludag University, Medical Faculty, Department of Endocrinology and Metabolism, Turkey, 2Uludag University, Medical Faculty, Department of Bio-Statistics, Turkey, 3Uludag University, Medical Faculty, Department of Pathology, Turkey

Bone/Calcium

P256

THE CHANGE OF BONE MINERAL DENSITY IN POSTMENOPAUSAL WOMEN TREATED BY COMBINED AGENT ALENDRONATE AND ALFACALCIDOL ASSESSED BY DIGITAL X-RAY RADIOGRAMMETRY

Corina Galesanu1 , Natalia Lisnic1, Mihail-Romeo Galesanu2, Ciprian Ciubotariu1, Roxana-Gabriela Galesanu2, Rodica Vasilica3, Dan Radu3, Dan Ursuleanu31Endocrinology, University of Medicine and Pharmacy "Gr.T.Popa", Romania, 2Osteodensitometry, Centre of Imaging and Radiologic Diagnosis, Romania, 3Endocrinology, County Hospital, Romania

Bone/Calcium

P257

Primary hiperparathyroidism surgery: team report 2002-2008

Miguel Allen1 , Ana Rafael1, Carlos Xió1, Luís Fernandes1, Joaquim Torrinha11Hospital de Egas Moniz, Portugal

Bone/Calcium

P258

Growth Hormone Secretory status and Bone Mineral Content in postmenopausal women

Akbar Aliasgarzadeh1 , Majid Mobassery1, Mehrnosh Mobasseri11Tabriz University (Medical Sciences), Iran, Islamic Republic of

Bone/Calcium

P259

Vitamin D status in healthy postmenopausal Iranian women

mitra niafar1 , naser aghamohamadzade1, majid mobasseri11Tabriz University of Medical sciences, Iran, Islamic Republic of

Bone/Calcium

P260

Could a neonatal hypocalcamia have a cultural origin?

Elke Mueller1 , Klaus Niethammer1, Gudrun Schmiedel1, Carl-Joachim Partsch11Klinikum Esslingen, Klinik fuer Kinder und Jugendliche, Esslingen, Germany

Bone/Calcium

P261

BONE MINERAL DENSITY AND BONE METABOLISM IN HEMODIALYSIS PATIENTS. CORRELATION WITH PTH, 25OHD3 AND LEPTIN.

Antonis Polymeris1 , Helen Karga1, Eirini Grapsa21Alexandra Hospital, 2nd Dpt of Endocrinology, Greece, 2Alexandra Hospital, Renal Unit, Greece

Bone/Calcium

P262

Thyrotoxicosis presenting as severe life-threatening hypocalcaemia – a case report

Vooi-Lee Loh1 , Edney Boston-Griffiths1, Andrew Rodin1, Steve Hyer11St. Helier Hospital, United Kingdom

Bone/Calcium

P263

BONE RESORPTION AND ANTIRESORPTIVE EFFECT OF BISPHOSPHONATES RELATED TO HOMOCYSTEINAEMIA

Tijana Icin1 , Branka Kovacev-Zavisic1, Milica Medic-Stojanoska1, Velibor Cabarkapa2, Jovanka Novakovic-Paro1, Ivana Bajkin11Clinic of endocrinology, diabetes and metabolic diseases, Clinical Centre of Vojvodina, Serbia, 2Centre of laboratory medicine, Clinical Centre of Vojvodina, Serbia

Bone/Calcium

P264

A simple method for osteoporotic fracture risk assessment in women of all ages, using computed clinical and densitometrical data

George Dorin Pop1 , Stelian Petcu1, Paul Lazar1, Marius Mihaila1, Ileana Duncea11University of Medicine and Pharmacy Cluj-Napoca, Romania

Bone/Calcium

P265

LIPID LEVELS BEFORE AND AFTER RADICAL TREATMENT OF PRIMARY HYPERPARATHYROIDISM

Aleksandra Kendereski1 , Dragan Micic1, Goran Cvijovic1, Svetlana Zoric1, Mirjana Sumarac-Dumanovic1, Danica Stamenkovic- Pejkovic11Institute of Endocrinology, Diabetes and diseases of metabolism, Serbia

Bone/Calcium

P266

VITAMIN D LEVELS IN YOUNG HEALTLY PREMENOPAUSAL FEMALES IN SLOVAKIA

P Vanuga1 , Z Killinger2, P Masaryk3, S Tomkova4, Z Kmecova5, V Spustova6, A Stecova7, J Payer21Osteocentre, National Institute of Endocrinology and Diabetology, Slovakia, 25th Clinic of Internal Medicine, Faculty Hospital of Comenius University, Slovakia, 3National Institute of Rheumatic Diseases, Slovakia, 4Osteocentre, Slovakia, 5Osteocentre, FD Roosevelt Faculty Hospital, Slovakia, 6Clinic of Pharmacotherapy, Slovak Medical University, Slovakia, 7Department of Laboratory Medicine, Medirex, Slovakia

Clinical case reports and clinical reports

P267

Graves' disease accompanied by pheochromocytoma presenting with normal levels of catecholamines: Report of a case

Sang-Yong Kim1 , Hak-Yeon Bae11Chosun university, Korea, Republic of

Clinical case reports and clinical reports

P268

Toxic liver damage after antithyroid drugs – 2 cases. The role of 131-I in treatment.

Renata Orlowska-Florek, Marek Grzywa11Department of Internal Medicine, Poland

Clinical case reports and clinical reports

P269

LYMPHOCYTIC HYPOPHYSITIS CASE WHO DEVELOPED EMPTY SELLA TO FOLLOW UP

Sebila Dokmetas1 , Fatih Kilicli1, Meryem Timucin1, Fettah Acibucu11Cumhuriyet University, Faculty of Medicine, Department of Endocrinology, Turkey, 2Cumhuriyet University, Faculty of Medicine, Department of Endocrinology, Turkey, 3Cumhuriyet University, Faculty of Medicine, Department of Internal Medicine, Turkey, 4Cumhuriyet University, Faculty of Medicine, Department of Internal Medicine, Turkey

Clinical case reports and clinical reports

P270

Liver manifestation of poorly controlled Type 1 Diabetes Mellitus: Hepatic glycogenosis

Serkan Yener1 , Erdener Ozer2, Ozlem Yuce1, Firat Bayraktar1, Sena Yesil11Dokuz Eylul University, Division of Endocrinology, Turkey, 2Dokuz Eylul University, Department of Pathology, Turkey

Clinical case reports and clinical reports

P271

CONCURRENT THYROİD MEDULLARY, PAPILLARY CARCİNOMA AND HASHIMOTO THYROIDITIS: CASE REPORT

Kamile GUL1 , Didem Ozdemir SEN1, Nevzat Serdar UGRAS2, serap S. INANCLI1, Reyhan ERSOY1, Bekir CAKIR11Ankara Ataturk Education and Research Hospital, Department of Endocrinology and Metabolism, Turkey, 2Ankara Ataturk Education and Research Hospital, Department of Pathology, Turkey

Clinical case reports and clinical reports

P272

The peripheral primitive neuroectodermal tumor (PNET) with neuroendocrine differentiation-case presentation

Muresan Anca Maria1 , Lazar Elena1, Dema Alis1, Faur Alexandra1, Cornea Remus1, Herman Diana1, Suciu Cristian1, Sargan Izabella11University of Medicina and Pharmacy, Romania

Clinical case reports and clinical reports

P273

TRANSIENT ISCHEMIC ATTACK AFTER ORAL L-THYROXINE LOADING TEST: A CASE REPORT

Özen Öz Gül1 , Sinem Kiyici1, Oguz Kaan Ünal1, Soner Cander1, Ali Nizamoglu2, Erdinc Ertürk1, Sazi Imamoglu11Endocrinology and Metabolism Department, Uludag University, Faculty of Medicine, Turkey, 2Internal Medicine, Uludag University, Faculty of Medicine, Turkey

Clinical case reports and clinical reports

P274

Hypopituitarism revealed after repetitive hyponatremia as complication of hemorrhagic fever

Matej Zavrsnik1 , Tanja Kok11University Clinical Center Maribor, Slovenia

Clinical case reports and clinical reports

P275

Paget’s disease of sacrum : A case report

Goknur Yorulmaz1 , Aysen Akalin1, Banu Sensoy Serbetci21Eskisehir Osmangazi University, Department of Endocrinology, Turkey, 2Eskisehir Osmangazi University, Department of Radiology, Turkey

Clinical case reports and clinical reports

P276

Possible Effects of IGF-1 and IGF-3 In The Development Of Growth Failure, Type 2 Diabetes Mellitus and Severe Insulin Resistance In A Case of Seckel Syndrome

Nur Kebapci1 , Kevser Onbasi1, Goknur Yorulmaz1, Belgin Efe1, Hikmet Basmak21Eskisehir Osmangazi University, Department of Endocrinology, Turkey, 2Eskisehir Osmangazi University, Department of Ophthalmology, Turkey

Clinical case reports and clinical reports

P277

Polyuria as a main feature of parathyroid crisis due to parathyroid glands hyperplasia

Oleg Bogatyriow1, Richard Parhimovich1, Irina Kotova11Moscow Regional Research Clinical Institute, Russian Federation

Clinical case reports and clinical reports

P278

Cushing syndrome caused by topical corticosteroids coexistent with pituitary incidentaloma – case report

Monika Karczewska-Kupczewska 1 , Agnieszka Adamska1, Irina Kowalska1, Maria Górska11Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, Poland

Clinical case reports and clinical reports

P279

Long-term Follow-up of A 46XX Case with Congenital Adrenal Hyperplasia and Male Gender Identity

Nur Kebapci1 , Belgin Efe1, Mahmut Kebapci2, Turgut Dönmez3, Cengiz Çetin4, Hikmet Hassa51Eskisehir Osmangazi University, Department of Endocrinology, Turkey, 2Eskisehir Osmangazi University, Department of Radiology, Turkey, 3Eskisehir Osmangazi University, Department of Urology, Turkey, 4Eskisehir Osmangazi University, Department of Plastic Surgery, Turkey, 5Eskisehir Osmangazi University, Department of Gynecology, Turkey

Clinical case reports and clinical reports

P280

AN UNUSUAL PRESENTATION OF AUTOIMMUNE POLYENDOCRINE SYNDROME: A CASE REPORT

Oguz Kaan Ünal1 , Sinem Kiyici1, Tunay Sentürk2, Tülay Sahin3, Mahmut Yavuz4, Murat Kiyici5, Sazi Imamoglu11Department of Endocrinology and Metabolism, Turkey, 2Department of Cardiology, Turkey, 3Department of Haematology, Turkey, 4Department of Rheumatology, Turkey, 5Department of Gastroenterelogy, Turkey

Clinical case reports and clinical reports

P281

Amiodarone-induced thyrotoxicosis – case report

Selma B Souto1 , Maria J Matos1, Paula Freitas1, Joana Queirós1, Ângela Magalhães1, Daniel Carvalho-Braga1, José Luís Medina11Endocrinology department, São João Hospital, Portugal

Clinical case reports and clinical reports

P282

BREAST METASTASES BY MEDULLARY THYROID CARCINOMA: CASE REPORT WITH AN UPDATE

ELISA MOYA CHIMENTI1 , BEATRIZ LECUMBERRI SANTAMARÍA1, JOSE ANTONIO ROSADO SIERRA1, BEATRIZ BARQUIEL ALCALÁ1, LUIS FELIPE PALLARDO SÁNCHEZ1, CRISTINA ÁLVAREZ ESCOLÁ11LA PAZ UNIVERSITARY HOSPITAL, Spain

Clinical case reports and clinical reports

P283

NESIDIOBLASTOSIS IN A PATIENT WITH GASTRINOMA

CRISTINA ÁLVAREZ ESCOLÁ1 , ELISA MOYA CHIMENTI1, VIRGINIA MARTÍN BORGE1, MARÍA GARCÍA DOMÍNGUEZ1, SUSANA AYUELA1, LUIS FELIPE PALLARDO SÁNCHEZ11LA PAZ UNIVERSITARY HOSPITAL, Spain

Clinical case reports and clinical reports

P284

Common variable immune deficiency as a rare cause of osteoporosis

Kevser Onbasi1 , Nur Kebapci1, Belgin Efe11Eskisehir Osmangazi University, Turkey

Clinical case reports and clinical reports

P285

TREATMENT OF METASTATIC MEDULLARY THYROID CARCINOMA WITH SORAFENIB

Philippos Kaldrymides1 , Ifigenia Kostoglou-Athanassiou1, Anastasios Goudouvas1, Eirini Veniou1, Theodosia Bakola1, Anastasia Agelopoulou1, Dimitrios Thomas1, Nikolaos Ziras21Department of Endocrinology, Metaxa Hospital, Greece, 2Department of Internal Medicine, Metaxa Hospital, Greece

Clinical case reports and clinical reports

P286

Gasser Ganglion as Pituitary Tumor- case report

Mara Carsote1 , Dan Peretianu2, Adriana Gruia3, Cristina Ene4, Dan Hortopan4, Catalina Poiana1,41Carol Davila University of Medicine and Pharmacy, Romania, 2SCM Povernei, Romania, 3Medlife Medical Centre, Romania, 4CI Parhon National Institute of Endocrinology, Romania

Clinical case reports and clinical reports

P287

Progression of Endocrine Hypofunction: A case of Polyglandular Autoimmune Syndrome Type 2

Risheka Ratnasabapathy1,2 , Akila De Silva11Hillingdon Hospital, United Kingdom, 2Imperial College, United Kingdom

Clinical case reports and clinical reports

P288

Retroesophageal Parathyroid Adenoma – Scintigraphic and intraoperative scintimetric localization of an ectopic parathyroid adenoma with Tc-99m Tetrofosmin: A Case Report

V Capova1 , J Lepej1, I Marin1, M Kudlac211Institute of Nuclear and Molecular Medicine, Slovakia, 22-nd Clinic of Surgery, Medical Faculty UPJŠ, Slovakia

Clinical case reports and clinical reports

P289

Glucocorticoid resistance syndrome: treatment with Ketoconazole, an efficient therapy solution – case report

Erika-Emoke Molnar1 , Cristina Ghervan1, Georgeta Hazi1, Ileana Duncea11University of Medicine and Pharmacy “Iuliu Hateganu”, Romania

Clinical case reports and clinical reports

P290

Intramuscular testosterone undecanoate – the experience of 11 years

Michael Zitzmann1 , Farid Saad1,2, Eberhard Nieschlag11University Clinics, Germany, 2Medical University, United Arab Emirates, 3BayerScheringHealthCare, Germany

Clinical case reports and clinical reports

P291

The R106C mutation of the V2 vasopressor receptor gene (AVPR2) causing X linked Congenital Nephrogenic Diabetes Insipidus (NDI) is responsive to short term desmopressin (dDAVP) challenge.

Marinos Fysekidis1, Jean-Jacques Boffa2, Laurent Baud1, Jean-Philippe Haymann11Tenon Hospital,Service d' Explorations Fonctionnelles Multidisciplinaires, France, 2Tenon Hospital,Service de Néphrologie et Dialyses, France

Clinical case reports and clinical reports

P292

Clinical analysis of 150 patients with pituitary insufficiency (20 years experience)

cristina preda1 , letitia leustean1, maria-christina ungureanu1, cristina cristea1, voichita mogos1, corina galesanu1, carmen vulpoi1, eusebie zbranca11University of medecine and Pharmacy "gr.T.Popa", Romania

Clinical case reports and clinical reports

P293

Prevalence and peculiarity of arterial hypertension treatment in acromegaly patients.

Galina Melnichenko1, Abram Syirkin1, Vyachelav Pronin1, Alexey Svet1, Ekaterina Chaplyigina1, Evgeniy Gitel1, Yuriy Poteshkin11I.M. Sechenov Moscow Medical Academy, Russian Federation

Clinical case reports and clinical reports

P294

The Ramadan: do Muslim diabetes patients adhere to their religion or to the doctor?

Guven Yildiz2,1 , Yeter Ozturk3,2, Marina Hertogen3, Veerle Van Vlaslare3, Dirk Avonts11University of Antwerp, Belgium, 2Huisartsenpraktijk Vijfhoek, Belgium, 3Plantinhogeschool, Belgium

Clinical case reports and clinical reports

P295

Adherence of internists and family physicians to SEMT guidelines for type 2 diabetes mellitus in Turkey

Ilhan Satman1 , Sazi Imamoglu2, Candeger Yilmaz3, R. Demet Ozkaya1, Oktay Ozdemir11Istanbul University Istanbul Faculty of Medicine, Turkey, 2Uludag University Faculty of Medicine, Turkey, 3Ege University Faculty of Medicne, Turkey

Clinical case reports and clinical reports

P296

Subclinical hypothyroidism as a cardiovascular risk factor

Sinziana Ghita11University Transilvania, Romania

Clinical case reports and clinical reports

P297

Sustained response to interferon alpha in a patient with advanced metastatic seritonin secreting endocrine tumour:- case report

Joy Ardill1,2 , Brian Johnston1, David McCance1, Martin Eatock31Royal Victoria Hospital, United Kingdom, 2Queens University Belfast, United Kingdom, 3Belfast Cancer Centre, United Kingdom

Clinical case reports and clinical reports

P298

PRIMARY HYPERPARATHYROIDISM IN THE EASTERN BLACK SEA REGION OF TURKEY: A DESCRIPTION OF 101 CASES

CIHANGIR EREM1, MUSTAFA KOCAK1, ARIF B. HACIHASANOGLU1, IRFAN NUHUOGLU1, OZGE UCUNCU1, S. TUBA KAPLAN1, H. ONDER ERSOZ11Karadeniz Technical University, Medical Faculty, Endocrinology and Metabolism Department, Turkey

Clinical case reports and clinical reports

P299

NUROENDOCRINE TUMOURS OF UNUSUALLOCALIZATION

Malgorzata Trofimiuk1 , Alicja Hubalewska-Dydejczyk1, Dorota Pach1, Anna Sowa-Staszczak1, Piotr Szybinski2, Jan Kulig2, Ryszard Anielski3, Stanislaw Cichon3, Maciej Matlok4, Danuta Karcz4, Wieslaw Bonicki51Chair and Department of Endocrinology, Medical College, Jagiellonian University, Poland, 2Department of Gastrointestinal Surgery, Medical College, Jagiellonian University, Poland, 3Endocrine Surgery, Medical College, Jagiellonian University, Poland, 4Department of Endoscopic Surgery, Medical College, Jagiellonian University, Poland, 5Department of CNS Neoplasms, Oncology Centre, Poland

Clinical case reports and clinical reports

P300

Successful pregnancy in a patient with Carney’s Complex, Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and biochemical cortisol excess.

David Cole1 , Steven Soule11Christchurch Hospital, New Zealand

Clinical case reports and clinical reports

P301

HUNGRY BONE SYNDROME FOLLOWING THYROIDECTOMY FOR THYROTOXICOSIS: CASE REPORT

Sharimini Ramasamy1 , Ahtzaz Hassan1, Charles Williams11William Harvey Hospital, United Kingdom

Clinical case reports and clinical reports

P302

Paraneoplastic Cushing’s syndrome due to prostate cancer – a rare occurrence

Subash Sivaraman1 , David Jenkins11Worcestershire royal hospital, United Kingdom

Clinical case reports and clinical reports

P303

Large intrathoracic goiter mimicking lung cancer

Kevser Onbasi1 , Aysen Akalin1, Göknur Yorulmaz1, Nur Kebapci1, Belgin Efe11Eskisehir Osmangazi University School Of Medicine, Turkey

Clinical case reports and clinical reports

P304

Double primary ovarian malignancies in a patient with bipolar disease complicating Swyer Syndrome

Evangelia Zapanti1 , Athanasia Giakioumi1, Konstantinos Terzidis1, Nikolaos Thomakos2, Alexandros Rodolakis2, P Grigori3, Maria Alevizaki11Department of Clinical Therapeutics, Alexandra hospital, Athens University School of Medicine, Greece, 21st Department of Obstetrics- Gynecology, Athens University School of Medicine, Alexandra hospital, Greece, 3Department of Genetics, Alexandra hospital, Greece

Clinical case reports and clinical reports

P305

THREE CASES WITH INAPPROPRIATE TSH SYNDROME

Sebila Dokmetas1 , Fatih Kilicli1, Fettah Acibucu1, Mahmut Ucar11Cumhuriyet University, Faculty of Medicine, Department of Endocrinology,, Turkey, 2Cumhuriyet University, Faculty of Medicine, Department of Endocrinology,, Turkey, 3Cumhuriyet University, Faculty of Medicine, Department of Internal Medicine, Turkey, 4Cumhuriyet University, Faculty of Medicine, Department of Internal Medicine, Turkey

Clinical case reports and clinical reports

P306

STROMAL LUTEOMA OF THE OVARY. CASE REPORT.

Selma B Souto1 , Daniel Carvalho-Braga1, Pedro Vieira Baptista2, Ana S Fernandes2, Jorge Beires2, José Luís Medina11Endocrinology departement, São João Hospital, Portugal, 2Obstetrics and Gynecology Department, São João Hospital, Portugal

Clinical case reports and clinical reports

P307

Coincidence of Primary Hyperaldosteronism with Thyrotoxic Nodular Goiter Presenting as Hypokalemic Periodic Paralysis; Complicating or Mimicking One Another?

Inan Anaforoglu1 , Ekrem Algün11Department of Endocrinology; Trabzon Numune Training and Research Hospital, Turkey

Clinical case reports and clinical reports

P308

HYPERGONADOTROPIC HYPOGONADISM DUE TO VANISHING TESTIS SYNDROME – CASE REPORT

Selma B Souto1 , Daniel Carvalho-Braga1, José Luís Medina11Endocrinology departement, São João Hospital, Portugal

Clinical case reports and clinical reports

P309

A case of giant-cell jaw tumour and primary hyperparathyroidism

Voichita Mogos1 , Eugenia Popescu1, Teodora Popa1, Cipriana Stefanescu1, Eusebie Zbranca1, Alexandru Grigorovici1, Sultana Mihailovici1, Dumitru Branisteanu11University of Medicine and Pharmacy "Gr.T.Popa", Romania

Clinical case reports and clinical reports

P310

α-Adrenergic blockade with Doxazosin – Case report

Maria Raquel Carvalho, Teresa Dias1, António Pedro Machado2, Rui Esteves3, Isabel do Carmo11Endocrinology, Diabetes and Metabolism Department, Hospital de Santa Maria, Portugal, 2Internal Medicine 1 Department, Hospital de Santa Maria, Portugal, 3Surgery Department 1, Hospital de Santa Maria, Portugal

Clinical case reports and clinical reports

P311

Graves´ Disease and Thymic Hyperplasia – Case Report

Maria Raquel Carvalho, Teresa Dias1, Fernando Baptista1, Isabel do Carmo11Endocrinology, Diabetes and Metabolism Department, Portugal

Clinical case reports and clinical reports

P312

CASE REPORT: PAPILLARY THYROID CARCINOMA IN A PATIENT WITH PENDRED SYNDROME

Ayten OGUZ1, Kamile GUL1, Serap S.INANCLI1, Birol KORUKLUOGLU2, Reyhan ERSOY1, Bekir CAKIR11Ankara Ataturk Education and Research Hospital, Department of Endocrinology and Metabolism, Turkey, 2Ankara Ataturk Education and Research Hospital, Department of 2.General Surgery, Turkey

Clinical case reports and clinical reports

P313

The study of a immunohistochemical aggresivity marker in mammary carcinomas

Muresan Anca Maria1 , Lazar Elena1, Dema Alis1, Taban Sorina1, Cornianu Marioara1, Costi Simona1, Cioroboreanu Ramona1, Sargan Izabella11University of Medicine and Pharmacy, Romania

Clinical case reports and clinical reports

P314

Schmidt’s Syndrome Atypical Case.

Larisa Dzeranova1, Olga Gerasimenko11National Research Centre for Endocrinology, Russian Federation

Clinical case reports and clinical reports

P315

Non-insulinoma pancreatogenic hypoglycemia syndrome (NIPHS) – recently described disease entity. Case report.

Aldona Kowalska1 , Iwona Palyga1, Danuta Gasior-Perczak1, Jacek Sygut1, Janusz Sluszniak1, Stanislaw Gozdz11Holycross Cancer Centre, Poland

Clinical case reports and clinical reports

P316

Malignant pheochromocytoma with brain metastases and coexisting meningioma – case report.

Aldona Kowalska1 , Katarzyna Lizis-Kolus11Holycross Cancer Centre, Poland

Clinical case reports and clinical reports

P317

Postmenopausal hyperandrogenism: report of two cases

Miguel Paja1 , Aitzol Lizarraga1, Nerea Egaña1, Rafael Ibarrola2, Alvaro Gorostiaga31Endocrinología. Hospital de Basurto, Spain, 2Anatomía Patológica. Hospital de Basurto, Spain, 3Ginecología. Hospital de Basurto, Spain

Clinical case reports and clinical reports

P318

Prader-Willi syndrome - case report

Denise Rosso1 , Arnaud Resende1, Alisson Valle1, Fauzi Neto1, Ana Paula Zanini1, Alberto Arbex11Federal University of Rio de Janeiro, Brazil, 2Institute of Medical Research - IPEMED, Brazil

Clinical case reports and clinical reports

P319

Dwarfism and Female Extenal Genitalia due to Congenital Partial Hypopituitarism in a 46XY Seckel Syndrome with Microcephaly and Multiple Skeletal Deformities.

Nur Kebapci1 , Belgin Efe1, Ayten Yakut2, Baki Adapinar3, Hikmet Basmak41Eskisehir Osmangazi University, Department of Endocrinology, Turkey, 2Eskisehir Osmangazi University, Department of Pediatric Neurology, Turkey, 3Eskisehir Osmangazi University, Department of Radiology, Turkey, 4Eskisehir Osmangazi University, Department of Ophthalmology, Turkey

Clinical case reports and clinical reports

P320

A Case of Adrenomyeloneuropathy and Addison Disease

Goknur Yorulmaz1 , Nur Kebapci1, Kevser Onbasi1, Aysen Akalin1, Belgin Efe1, Demet Ozbabalik21Eskisehir Osmangazi University, Department of Endocrinology, Turkey, 2Eskisehir Osmangazi University, Department of Neurology, Turkey

Clinical case reports and clinical reports

P321

A PRIMARY DIFFERENTIATED CARCINOMA OF ECTOPIC MEDIASTINAL THYROID:REPORT OF TWO CASES

ARIBI YAMINA1 , OULD KABLIA SAMIA1, AKROUF ROSA1, KEMALI ZAHRA11central hospital of the army department of endocrinology, Algeria

Clinical case reports and clinical reports

P322

TRİPLE X SYNDROME (47, XXX) WITH INFERTILITE AND OBESITY

MUSTAFA KOCAK1 , CIHANGIR EREM1, IRFAN NUHOGLU1, FIGEN CELEP2, OZGE UCUNCU1, MUSTAFA KARAGULLE1, H. ONDER ERSOZ11Karadeniz Technical University, Medical Faculty, Endocrinology and Metabolism Department, Turkey, 2Karadeniz Technical University, Medical Faculty, Medical Biology and Genetics Department, Turkey

Clinical case reports and clinical reports

P323

TREATMENT OF A CASE OF METASTATIC THYROID CANCER WITH SORAFENIB

Philippos Kaldrymides1 , Ifigenia Kostoglou-Athanassiou1, Anastasios Goudouvas1, Dimitrios Thomas1, Athanasia Tertipi1, Nikolaos Ziras21Department of Endocrinology, Metaxa Hospital, Greece, 2Department of Internal Medicine, Metaxa Hospital, Greece

Clinical case reports and clinical reports

P324

INSULIN AUTOIMMUNE SYNDROME IN A PATIENT WITH TYPE 2 DIABETES – A CASE REPORT

Leone Duarte1,2 , José Silva-Nunes1, Zulmira Peerally2, Lurdes Gomes2, Maria- Cristina Rogado2, Ana-Filipa Lopes1, João-Filipe Raposo2, Fernando Malheiro11Hospital Curry Cabral, Portugal, 2Portuguese Diabetes Association, Portugal

Clinical case reports and clinical reports

P325

Malignant struma ovarii - a case report

Maria Gryczynska1 , Magdalena Matysiak-Grzes1, Aleksandra Klimowicz1, Rafal Czepczynski1, Pawel Gut1, Katarzyna Wachowiak-Ochmanska1, Blazej Nowakowski1, Jerzy Sowinski11Poznan University of Medical Sciences, Poland

Clinical case reports and clinical reports

P326

Cushing’s Syndrome in a Patient with Bilateral Adrenal Masses and Pituitary Incidentaloma- Case Report

Catalina Poiana1,2 , Mara Carsote1, Raluca Trifanescu1,2, Dan Hortopan2, Andra Caragheorgheopol2, Ramona Samoila2, Bogdan Stanescu1,21Carol Davila University of Medicine and Pharmacy, Romania, 2CI Parhon National Institute of Endocrinology, Romania

Clinical case reports and clinical reports

P327

Cerebrospinal fluid rhinorrhoea following dopamine agonist therapy for large macroprolactinoma

Mahamood Edavalath1 , Ravi Nannapaneni2, M Keston Jones11Singleton Hospital, United Kingdom, 2University Hospital of Wales, United Kingdom

Comparative endocrinology

P328

Characterization of a vasoactive intestinal peptide receptor type 2 (VPAC2R) in an early jawed vertebrate, sturgeon (Acipenser schrenckii)

Billy KC Chow1 , Elisa HY Lau1, Leo TO Lee11The University of Hong Kong, China

Comparative endocrinology

P329

Influence of orchidectomy and testosterone replacement on adrenal cortex activity in the Saharan gerbil Gerbillus tarabuli

Yamina Zatra1 , Nawel Aknoun1, Farida Khammar1, Zaina Amirat11USTHB, Algeria

Comparative endocrinology

P330

Comparative Analyses between the Glycoprotein-Hormone Receptors and the orphan Leucine-rich repeat containing G-protein coupled receptor 4 (LGR4)

Gunnar Kleinau1 , Annette Grüters2, Heike Biebermann2, Gerd Krause11Leibniz-Institut für Molekulare Pharmakologie, Germany, 2Institute for Experimental Pediatric Endocrinology, Charité Universitätsmedizin, Germany

Comparative endocrinology

P331

Diabetes Insipidus Prevalence in the Republic o Uzbekistan according to National Register

said Ismailov1 , Zamira Khalimova1, Yulduz Urmanova1, Dinara Alieva1, Gulchekhra Narimova11Institute of Endocrinology, Uzbekistan

Comparative endocrinology

P332

Cortisol and Biochemical Changes in Pregnant Women

Oluyemi Akinloye1 , Olabisi Motunrayo Ogunkoya1, Pius Dolapo Oparinde11Ladoke Akintola University of Technology, Nigeria

Diabetes and cardiovascular

P333

Characterization of a young population of type 1 diabetics

Alexandra Vieira1 , Ana Fagulha1, Luisa Barros1, Júlia Figueiredo1, Jacinta Santos1, Mariana Martinho2, Francisco Carrilho1, Manuela Carvalheiro11Endocrinology, Diabetes and Metabolism Department, Coimbra's University Hospital. EPE, Portugal, 2Endocrinology Department, Portuguese Oncology Institue, FJ, EPE, Portugal

Diabetes and cardiovascular

P334

How Diabetic Children's Families inject them insulin at home

Marjan Kouhnavard1 , Mahin Kohankary2, Alavieh Razavi31Iran University of Medical Sciences, Iran, Islamic Republic of, 2Iranian Society of Diabetes, Iran, Islamic Republic of, 3Uroumieh University of Medical Sciences, Iran, Islamic Republic of

Diabetes and cardiovascular

P335

HLA DQB1 AND HLA DQA1 GENOTYPES PREVALENCE IN CHILDREN AND ADOLESCENCE WITH NEW-ONSET DIABETES TYPE 1 IN THE LOWER SILESIA REGION.

Teresa Zak1 , Malgorzata Malodobra1, Agnieszka Zubkiewicz1, Anna Noczynska11Depertment of Endocrinology and Diabetology for Children and Adolescents, Poland

Diabetes and cardiovascular

P336

Comparative Molecular Analysis of TRAIL Ligand and Receptor Expression Profiles in Cyclophosphamide versus Streptozotocin-Induced Diabetes in Non- Obese Diabetic (NOD) Mice

Sevim KAHRAMAN1, Ercument DIRICE1, Ozlem ELPEK1, Mustafa Kemal BALCI1, Abdulkadir OMER2, Salih SANLIOGLU1, Ahter SANLIOGLU11Akdeniz University, Turkey, 2Harvard Medical School, United States

Diabetes and cardiovascular

P337

Association of IL-4 Promoter Polymorphisms in Taiwanese Patients with Type 2 Diabetes Mellitus

Ming-Yuh Shiau1, Chien-Ning Huang2, Kuo-Ting Ho3, Yih-Hsin Chang41Hung Kuang University, Taiwan, 2Chung Shan Medical University-Hospital, Taiwan, 3Chung Hsing University, Taiwan, 4Chung Shan Medical University, Taiwan

Diabetes and cardiovascular

P338

Saxagliptin added to a thiazolidinedione, metformin or a sulphonylurea improves glycaemic control in patients with inadequately controlled type 2 diabetes mellitus

Pierre Maheux1 , Elsie Allen2, Shoba Ravichandran2, James List2, Roland Chen21AstraZeneca ISMO Europe, Belgium, 2Clinical Research, Bristol-Myers Squibb, United States

Diabetes and cardiovascular

P339

Change of physical activity, diet habits and risk of diabetes after lifestyle intervention. Diabetes in Europe – Prevention using Lifestyle, Physical Activity, and Nutritional Intervention: The DePlan Project Krakow

Aleksandra Gilis-Januszewska, Alicja Hubalewska-Dydejczyk1, Beata Piwonska- Solska1, Zbigniew Szybinski1, Jaana Linstrom2, Marku Peltonen3, Peter Schwarz1, Noel Barengo2, Jaakko Tuomilehto21Chair and Department of Endocrinology Collegium Medicum, Jagiellonian University, Poland, 2Department of Public Health, University of Helsinki,, Finland, 3Diabetes Unit, Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute,, Finland, 4Department of Medicine III, Medical Faculty Carl Gustav Carus of the Technical University Dresden,, Germany

Diabetes and cardiovascular

P340

Limits in using brain natriuretic peptide (BNP) as a biomarker of acute right ventricular dysfunction in pulmonary embolism

Alina Mihaela Pascu1 , Mariana Radoi2, Mihail Coculescu31Transilvania University, Faculty of Medicine, Department of Pathophysiology, Clinic of Cardiology, Romania, 2Transilvania University, Faculty of Medicine, Department of Internal Medicine, Clinic of Cardiology, Romania, 3Carol Davila University of Medicine and Pharmacy, Department of Endocrinology, C.I. Parhon Institute of Endocrinology, Romania

Diabetes and cardiovascular

P341

DETERMINATION OF OXIDIZED LDL AND ANTI OXIDIZED LDL ANTIBODY IN PATIENTS WITH TYPE 2 DIABETES

mitra niafar1 , manouchehr nakhjavani1,2, alireza esteghamati11Tabriz University of Medical sciences, Iran, Islamic Republic of, 2Tehran university of medical sciences, Iran, Islamic Republic of

Diabetes and cardiovascular

P342

Relationship between lipid oxidation and insulin resistance in type 2 diabetes mellitus

mitra niafar1 , manouchehr nakhjavani1, alireza esteghamati1, mehrshad abasi11Tabriz University of Medical sciences, Iran, Islamic Republic of, 2Tehran University of Medical sciences, Iran, Islamic Republic of

Diabetes and cardiovascular

P343

Role of Soluble Fas/Fas Ligand Pathway and Osteoprotegerin Levels in Patients with Diabetic Foot

Sibel Guldiken1, Bengur Taskiran1, Muzaffer Demir2, Armagan Tugrul1, Betul Ugur Altun11Trakya University Medical Faculty, Department of Endocrinology, Turkey, 2Trakya University Medical Faculty, Department of Hematology, Turkey

Diabetes and cardiovascular

P345

Evaluation of cronary artery disease prevalence in diabetic patients with no or atypical cardiac symptoms.

rasoul Zakavi1 , haleh rokni1, zohreh mousavi1, Mahdi taherpour1, reza rajabian1, mohamad khajeh dalooei11Mashad medical sience univercity, Iran, Islamic Republic of, 2razavi hospital, Iran, Islamic Republic of

Diabetes and cardiovascular

P346

Impaired glucose regulation and arterial stiffness.

Marina Shargorodsky11wolfson medical center and Sakler school of medicine, Tel-Aviv University, Israel

Diabetes and cardiovascular

P347

Association between polymorphisms in the promoter of heme oxygenase-1 and vascular complications in type 2 diabetic patients

Yong-Ho Lee1, Eun Seok Kang1, Chul Woo Ahn1, Bong Soo Cha1, Hyun Chul Lee11Yonsei University College of Medicine, Korea, Republic of

Diabetes and cardiovascular

P348

Paradoxical effects of GABA on glucose-stimulated insulin secretion from isolated islets in rat

Farzaneh Faraji Shahrivar, Asghar Ghasemi1, Fereshteh Motamedi2, Saleh Zahedi Asl11Endocrine Physiology Laboratory, Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University (M.C.), Iran, Islamic Republic of, 2Neurosciences Research Center, Shahid Beheshti University (M.C.), Iran, Islamic Republic of

Diabetes and cardiovascular

P349

INSPIRATORY MUSCLE STRENGTH IS CORRELATED WITH CARNITINE LEVELS IN TYPE 2 DIABETES

Fatih Kilicli1 , Hatice Sebila Dokmetas1, Ferhan Candan1, Sefa Levent Ozsahin1, Serdal Korkmaz1, Elvan Amasyali1, Koray Fakioglu1, Fettah Acibucu1, Kürsat Dal11Cumhuriyet University, Faculty of Medicine, Department of Endocrinology, Turkey, 2Cumhuriyet University, Faculty of Medicine, Department of Endocrinology, Turkey, 3Cumhuriyet University, Faculty of Medicine, Department of Nephrology, Turkey, 4Cumhuriyet University, Faculty of Medicine, Department of Chest Disease, Turkey, 5Cumhuriyet University, Faculty of Medicine, Department of Internal Medicine, Turkey, 6Cumhuriyet University, Faculty of Medicine, Department of Internal Medicine, Turkey, 7Cumhuriyet University, Faculty of Medicine, Department of Internal Medicine, Turkey, 8Cumhuriyet University, Faculty of Medicine, Department of Internal Medicine, Turkey, 9Cumhuriyet University, Faculty of Medicine, Department of Internal Medicine, Turkey

Diabetes and cardiovascular

P350

Mildronate positively affects compensation of diabetes in streptozotocin rats and alters iNOS gene expression in rat tissues.

Jelizaveta Sokolovska1 , Ivars Kalvinsh1, Jelena Sharipova1, Lasma Lauberte1, Nikolajs Sjakste11Latvian Institute of Organic Synthesis, Latvia

Diabetes and cardiovascular

P351

Local Atorvastatine may be Beneficial in the Treatment of the Wounds in Diabetic Rats

Erim Gulcan1 , Kasim Çayci2, Serdar Toker1, Esra G. Olgun1, Yusuf Ozay21Dumlupinar University School of Medicine, Department of Internal Medicine, Orthopaedics and Pathology, Turkey, 2Dumlupinar Univesity, Faculty of Sciences and Arts, Department of Biology, Turkey

Diabetes and cardiovascular

P352

CORONARY HEART DISEASE RISK REDUCTION IN OBESE PATIENTS SUBMITTED TO ADJUSTABLE GASTRIC BAND

Leone Duarte1 , José Silva-Nunes1, Ana-Filipa Lopes1, Cristina Santos1, José- Mário Coutinho1, Maria-Manuel Botelho1, António Albuquerque1, Fernando Malheiro11Hospital Curry Cabral, Portugal

Diabetes and cardiovascular

P353

ATHEROGENIC AND ANTI-ATHEROGENIC RISK MARKERS IN SUBJECTS WITH OBESITY AND/OR TYPE 2 DIABETES

Denise Rosso1 , Valeria Bender1, Valeria Furtado11Federal University of Rio de Janeiro, Brazil, 2Federal University of State of Rio de Janeiro, Brazil

Diabetes and cardiovascular

P354

Optimal Fasting Plasma Glucose Level For Diagnosis Of Diabetes In A Singaporean Population

Joan Khoo11Changi General Hospital, Singapore

Diabetes and cardiovascular

P355

ENDOGENOUS ESTROGEN LEVELS ARE ASSOCIATED WITH ENDOTHELIAL FUNCTION IN MALES INDEPENDENTLY OF LIPID LEVELS

Katerina Saltiki1,2 , Kimon Stamatelopoulos3, Paraskevi Voidonikola3, Emily Mantzou1, Christos Papamichael3, Maria Alevizaki1,21Endocrine Unit, Evgenidion Hospital, Athens University School of Medicine, Greece, 2Endocrine Unit, Dept Medical Therapeutics, Alexandra Hospital, Athens University School of Medicine, Greece, 3Vascular Laboratory, Dept of Medical Therapeutics, Alexandra Hospital, Athens University School of Medicine, Greece

Diabetes and cardiovascular

P356

Glucose intolerance and risk of cardiovascular disease: results of the 7.6 year follow-up of the Tehran Lipid and Glucose Study (TLGS)

Farzad Hadaegh1 , Davood Khalili1, Nooshin Fahimfar1, Maryam Tohidi1, Farhad Sheikholeslami1, Fereidoun Azizi21Prevention of metabolic disorders research centers, Research institute for endocrine sciences, Shahid Beheshti University (M.C.), Iran, Islamic Republic of, 2Endocrine research center, Research institute for endocrine sciences, Shahid Beheshti University (M.C.), Iran, Islamic Republic of

Diabetes and cardiovascular

P357

Pharmacokinetics of the Dipeptidyl Peptidase-4 Inhibitor Saxagliptin in Subjects with Renal Impairment

David Boulton1 , Angela Tang1, Chirag Patel1, Li Li1, Xiaohui Xu1, Ernst Frevert1, David Kornhauser11Bristol-Myers Squibb R&D, United States

Diabetes and cardiovascular

P358

Biphasic insulin aspart 30/70 improves glycaemic control in patients with type 2 diabetes: clinical practice experience from Indian subgroup of the IMPROVETM study

Unnikrishnan AG1 , Siddharth Shah2, Arthur Asirvatham3, Praful Chakkarwar5, Ashok Moharana5, Dheeraj Kapoor41Amrita Institute of Medical Sciences, India, 2Bhatia Hospital, India, 3Madurai Medical College, India, 4Artemis Health Institute, India, 5Novo Nordisk, India

Diabetes and cardiovascular

P359

Saxagliptin either as add-on therapy to metformin or as initial combination therapy with metformin improves glycaemic control in patients with type 2 diabetes

Andreas Pfützner1 , Irina Gurieva2, Mikhail Antsiferov3, Elsie Allen4, Shoba Ravichandran4, Roland Chen41Institute for Clinical Research and Development, Germany, 2Federal Bureau of Medicine and Social Expertise, Russian Federation, 3Endocrinology Dispensary, Russian Federation, 4Global Clinical Research, Bristol-Myers Squibb, United States

Diabetes and cardiovascular

P360

Effects of estrogen therapy on cardiovascular risk factor in transsexuals

Mara Bochetti1 , Laura Casalino2, Sergio Agosti2, Claudia Teti1, Francesco M. Minuto1, Diego Ferone11DISEM-CEBR, Italy, 2DIMI-Department of Cardiology, Italy

Diabetes and cardiovascular

P361

Carotid Intima Media Thickness and Serum Osteoprotegerin and RANKL Levels in Diabetic and Prediabetic Patients

Serife Mehlika Isildak, Anil Barak1, Yakup Yesilkaya1, Deniz Akata1, Omer Alper Gurlek11Hacettepe University Faculty of Medicine, Turkey

Diabetes and cardiovascular

P362

Klotho gene polymorphism may be a genetic risk factor for metabolic syndrome in men.

Constantinos Katsoulis1, Anthi Chatzikyriakidou1, Nektaria Xita1, Ioannis Georgiou1, Agathocles Tsatsoulis11University of Ioannina, Greece

Diabetes and cardiovascular

P363

CHEMOTHERAPY DOES NOT INFLUENCE MEASURES OF GLYCAEMIC CONTROL IN NON-DIABETIC PATIENTS AFFECTED BY ACUTE LEUKAEMIA

Vincenzo Triggiani1 , Edoardo Guastamacchia1, Vincenzo Liso2, Giorgina Specchia2, Francesco Resta3, Carlo Sabbà3, Brunella Licchelli1, Emilio Tafaro11Endocrinology. University of Bari, Italy, 2Ematology. University of Bari, Italy, 3Internal Medicine. University of Bari, Italy

Diabetes and cardiovascular

P364

PANCREATIC FUNCTION IN BETA-THALASSEMIC PATIENTS Vryonidou A, Loi V, Vasiliou G, Terzi T, Karagianni O, Tzioras C, Phenekos C Department of Endocrinology, Diabetes and Metabolism, Red Cross Hospital, Athens, Greece

Andromachi Vryonidou-Bompota, Vasiliki Loi1, Georgia Vasiliou1, Thomais Terzi1, Olympia Karagianni1, Costas Tzioras1, Costas Phenekos11Red Cross Hospital, Greece

Diabetes and cardiovascular

P365

Characterization of Type I Interferon (IFN) mediated diabetes sparing activity

Douglas Sobel1 , Behrouz Ahvazi1, Carol Pontzer21Georgetown University, United States, 2University of Maryland, United States

Diabetes and cardiovascular

P366

A comparison between adhesion molecules (as markers of inflammation) in identifying cardiovascular disease in postmenopausal women

Adela-Viviana Sitar-Taut1 , Mirela Cebanu1, Olga Soritau2, Carmen Stugren2, Dana Pop1, Dumitru Tudor Zdrenghea11University Of Medicine and Pharmacy “Iuliu Hatieganu”, Romania, 2Cancer Hospital “Prof I Chiricuta”, Romania

Diabetes and cardiovascular

P367

THE RELATIONSHIP BETWEEN HEMOGLOBIN LEVELS AND ENDOTHELIAL FUNCTIONS IN DIABETES MELLITUS

Alper Sonmez1 , M. Ilker Yilmaz2, Carmine Zoccali3, Mutlu Saglam4, Selim Kilic5, Gokhan Uckaya1, Tayfun Eyileten2, Mujdat Yenicesu2, Mustafa Kutlu11Gulhane Military Medical School, Department of Endocrinology and Metabolism, Turkey, 2ulhane Military Medical School, Department of Nephrology, Turkey, 3Nephrology, Dialysis and Transplantation Unit and CNR-IBIM Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension, Italy, 4Gulhane Military Medical School, Department of Radiology, Turkey, 5Gulhane Military Medical School, Department of Epidemiology, Turkey

Diabetes and cardiovascular

P368

Lack of association between polymorphisms at the adiponectin gene locus and type 2 diabetes as well as body mass index in Latvian population.

Janis Klovins1 , Ineta Kalnina1, Vitolds Mackevics3, Davids Fridmanis1, Liene Nikitina-Zake1, Valdis Pirags21Latvian Biomedical Research and Study Center, Latvia, 2University of Latvia and Department of Endocrinology, Pauls Stradins Clinical University Hospital, Latvia, 3Department of Internal Medicine, Faculty of Medicine, Riga Stradins University, Latvia

Diabetes and cardiovascular

P369

EPICARDIAL ADIPOSE TISSUE THICKNESS AND SERUM VISFATIN LEVELS IN PATIENTS WITH NEW DIAGNOSED PREDIABETES AND TYPE II DIABETES MELLITUS

Abdullah Taslipinar1 , Mine Y. Taslipinar2, Omer Azal3, Mustafa Sahin4, Levent Kebapcilar5, Levent Ozdemir6, Cagatay Savashan7, Gokhan Uckaya8, Cem Koz9, Halil Yaman10, Cengizhan Acikel11, Mustafa Kutlu121GATA Department of Endocrinology ve Metabolism, Turkey, 2DISKAPI HOSPITAL Department of Biochemistry, Turkey, 3GATA Department of Endocrinology ve Metabolism, Turkey, 4GATA Department of Endocrinology ve Metabolism, Turkey, 5GATA Department of Endocrinology ve Metabolism, Turkey, 6GATA Department of Family Medicine, Turkey, 7GATA Department of Family Medicine, Turkey, 8GATA Department of Endocrinology ve Metabolism, Turkey, 9GATA Department of Cardiology, Turkey, 10GATA Department of Biochemistry, Turkey, 11GATA Department of Public Health, Turkey, 12GATA Department of Endocrinology ve Metabolism, Turkey

Diabetes and cardiovascular

P370

THE RELATIONSHIP BETWEEN BODY MASS INDEX- LEFT VENTRICLE MASS INDEX- MYOCARDIAL PERFORMANCE INDEX IN TYPE 2 DIABETES

FATMA ALIBAZ ONER1 , ZEYNEP GURCAN1, ISIL UZUNHASAN1, MEHMET EMIN PISKINPASA1, MECDI ERGUNEY11ISTANBUL EDUCATION AND RESEARCH HOSPITAL, Turkey, 2UNIVERSITY OF ISTANBUL, CARDILOGY INSTITUE OF HASEKI, Turkey

Diabetes and cardiovascular

P371

Correlation between serum 25 hydroxy vitamin D3 and laboratory risk markers of cardiovascular diseases in type 2 diabetic patients

shokoufeh bonakdaran1 , Abdol-Reza varasteh11medical siences, Iran, Islamic Republic of, 2medical siences, Iran, Islamic Republic of

Diabetes and cardiovascular

P372

N-Acetylcysteine is able to reduce the oxidation status and the endothelial activation after a high-glucose content meal in patients with type 2 diabetes mellitus.

Andi Masha1 , Loredana Brocato1, Stefano Dinatale1, Cinzia Mascia2, Fiorella Biasi2, Valentino Martina11Department of Internal Medicine, Division of Endocrinology, University of Turin, Italy, 2Department of Clinical and Biological Sciences, University of Turin, Italy

Diabetes and cardiovascular

P373

Hyperhomocysteinemia may be a risk factor for diabetic foot ulcer development

Soner Solmaz1, Mehmet Erdogan2, Mustafa Kulaksizoglu3, Sencer Ganidagli1, Aybike Kosenli1, Hakan Sakalli1, Abdullah Canataroglu11Numune Education and Research Hospital, Department of Internal Medicine, Turkey, 2Ege University Medical School, Department of Endocrinology and Metabolism Disease, Turkey, 3Numune Education and Research Hospital, Department of Endocrinology, Turkey

Diabetes and cardiovascular

>P374

Incidence of Diabetic Ketoacidosis during Ramadan fasting in Benghazi-Libya

Rafik Elmehdawi1 , Mohammad Ehmida2, Hanan Elmagrehi31Al-Arab medical university, Libyan Arab Jamahiriya, 2Al-Jamahiriya hospital, Libyan Arab Jamahiriya, 37th of October hospital, Libyan Arab Jamahiriya

Diabetes and cardiovascular

P375

ECoRI POLYMORPHISM BUT NOT XbaI POLYMORPHISM OF APOLIPOPROTEIN B GENE IS ASSOCIATED WITH CAROTIS INTIMA MEDIA THICKNESS IN TYPE II DIABETIC PATIENTS

Meral Yüksel1, Seda Sancak2, Dilek Dereli Yazici2, Beste Özben3, Dilek Gogas-Yavuz2, Nefise Sema Akalin21Marmara University, Vocational School of Health Related Professions, Turkey, 2Marmara University, School of Medicine, Section of Endocrinology and Metabolism, Turkey, 3Marmara University, School of Medicine, Department of Cardiology, Turkey

Diabetes and cardiovascular

P376

Insulin-loaded lipid nanospheres surfaced with polysaccharides for oral delivery

Eliana B. Souto1 , Selma B. Souto21Universidade Fernando Pessoa, Faculty of Health Sciences, Portugal, 2Endocrinology Department, Hospital S. João, Portugal

Diabetes and cardiovascular

P377

INFLUENCE OF ADMISSION PLASMA GLUCOSE LEVEL ON SHORT AND LONG-TERM PROGNOSIS IN PATIENTS WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION

Violeta Mladenovic1 , Aleksander Djukic1, Marina Jovic2, Vladimir Zdravkovic2, Mirko Rosic31Center for endocrinology, diabetes and metabolic disesase, Internal Clinic, Clinical Center, Serbia, 2Center for cardiology, Internal Clinic, Clinical Center, Serbia, 3Institute for cardiology, Internal Clinic, Clinical Center, Serbia

Diabetes and cardiovascular

P378

The effect of glycemic control on mean platelet volume in patients with Type 2 Diabetes Mellitus

Alptekin Gürsoy1 , Cüneyd Anil1, Semra Aytürk1, Asli Nar1, Neslihan Bascil Tütüncü11Baskent University Faculty of Medicine, Department of Endocrinology and Metabolism, Turkey

Diabetes and cardiovascular

P379

Association between APOE genotype and hsCRP in Iranian population: Thehran, Lipid and glucose study

Maryam Daneshpour1 , Sara Behnami1, Mehdi Hedayati1, Fereidoun Azizi11Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University (MC), Iran, Islamic Republic of

Diabetes and cardiovascular

P380

Ca 19-9 LEVELS IN TYPE 2 DIABETES MELLITUS PATIENTS

Kamile GUL1 , Sevinc NAS1, Didem Ozdemir SEN1, Mehmet GUMUS2, Reyhan ERSOY1, Bekir CAKIR11Ankara Ataturk Education and Research Hospital, Department of Endocrinology and Metabolism, Turkey, 2Ankara Ataturk Education and Research Hospital, Department of Radiology, Turkey

Diabetes and cardiovascular

P381

PLASMINOGEN ACTIVATOR INHIBITOR 1 AND ATHEROSCLEROSIS IN DIABETES MELLITUS TYPE 2

Sanja Ilic1 , Nada Kostic1, Zorica Caparevic1, Jana Radojkovic1, Svetlana Jelic1, Djordje Marina11Clinical Centre Dr Dragisa Misovic, Serbia

Diabetes and cardiovascular

P382

COMBINED TREATMENT IN CHILDHOOD DIABETES COULD INFLUENCE REMISSION PERIOD

Ljiljana Saranac1 , Snezana Zivanovic1, Gordana Kostic1, Bojko Bjelakovic1, Martin Novak11Children's Clinic CC Nis, Serbia

Diabetes and cardiovascular

P383

Impact of age, gender, DM duration and BMI on metabolic control of T2DM patients in Jordan

FARES HADDAD1 , OMAR MALKAWI1, Abdallah Abdelaziz1, Khaldon Srehein1, Alia Izzat1, Reem Qadah1, Ala'a Rifa'i1, Niveen Foqaha11King Hussein Medical Center, Jordan

Diabetes and cardiovascular

P384

Retinol binding protein-4 is associated with TNF-α and not insulin resistance in subjects with type 2 diabetes mellitus and coronary heart disease

Nasser Al-Daghri1 , Omar Al-Attas1, Majed Alokail1, Hossam Draz1, Ahmed Bamakhramah1, Shaun Sabico11King Saud University, Saudi Arabia

Diabetes and cardiovascular

P385

Impact of metabolic syndrome, diabetes and prediabetes on cardiovascular events: Tehran Lipid and Glucose Study

Farzad Hadaegh1 , Gita Shafiee1, Asghar Ghasemi1, Parvin Sarbakhsh1, Fereidoun Azizi21Prevention of metabolic disorders research center, Research institute for endocrine sciences, Shahid Beheshti University (M.C), Iran, Islamic Republic of, 2Endocrine rsearch center, Research institute for endocrine sciences, Shahid Beheshti University (M.C), Iran, Islamic Republic of

Diabetes and cardiovascular

P386

NovoMix30® reduces hypoglycemic events with favorable weight change in poorly controlled type 2 diabetes patients: Results from Indian cohort of IMPROVETM Study

Sanjay Kalra1 , Unnikrishnan AG2, Ajay Kumar3, Ashok Moharana4, Vinay Prusty4, Manash Baruah51Bharti Hospital,, India, 2Amrita Institute of Medical Sciences, India, 3Diabetes Care & Research Center, India, 4Novo Nordisk, India, 5Excel Care Hospital, India

Diabetes and cardiovascular

P387

Plasma Thrombin-Activatable Fibrinolysis Inhibitor (TAFI) Antigen Levels in diabetic foot ulcers

Mehmet Erdogan1 , Soner Solmaz2, Abdullah Canataroglu2, Mustafa Kulaksizoglu3, Sevki Cetinkalp1, Gokhan Ozgen1, Fusun Saygili1, Candeger Yilmaz11Ege University Medical School, Department of Endocrinology and Metabolism Disease, Turkey, 2Numune Education and Research Hospital, Department of Internal Medicine, Turkey, 3Numune Education and Research Hospital, Department of Endocrinology, Turkey

Diabetes and cardiovascular

P388

Relationship between Adipocytokines and Cardiovascular Risk Factors in Patients with Type 2 Diabetes Mellitus

Sema Uslu1 , Nur Kebapci2, Mehmet Kara1, Cengiz Bal31Eskisehir Osmangazi University, Department of Biochemistry, Turkey, 2Eskisehir Osmangazi University, Department of Endocrinology, Turkey, 3Eskisehir Osmangazi University, Department of Biostatistics, Turkey

Diabetes and cardiovascular

P389

Prevalence of atopic profile in patients with type 1, type 2 and LADA Diabetes Mellitus

Erifili Hatziagelaki1 , Ioanna Koti2, Kyriaki Sideri2, Michael Makris2, Ekaterini Chliva2, Theofanis Economopoulos1, Dimitrios Kalogeromitros212nd Dept. of Internal Medicine & Research Institute, ''Attikon'' University Hospital, Medical School, University of Athens, Greece, 2Allergy Clinical Research Center, Allergy Unit, ''Attikon'' University Hospital, Medical School, University of Athens, Greece

Diabetes and cardiovascular

P390

Prevalence of cardiovascular risk polymorphisms and its association with microvascular complications in an adolescent type 1 diabetes population

Miguel Melo1 , Ana Fagulha1, Luisa Barros1, Jacinta Santos1, Alexandra Vieira1, Manuela Carvalheiro11University Hospital of Coimbra, Portugal

Diabetes and cardiovascular

P391

VISFATIN SEEMS NOT TO BE RELATED IN INSULIN RESISTANCE

Abdullah Taslipinar1 , Mine Y. Taslipinar2, Omer Azal3, Levent Kebapcilar4, Mustafa Sahin5, Gokhan Uckaya6, Y.Alper Sonmez7, Ozge Kucukerdonmez8, Mustafa Kutlu91GATA Department of Endocrinology and Metabolism, Turkey, 2DISKAPI HOSPITAL Department of Biochemistry, Turkey, 3GATA Department of Endocrinology and Metabolism, Turkey, 4GATA Department of Endocrinology and Metabolism, Turkey, 5GATA Department of Endocrinology and Metabolism, Turkey, 6GATA Department of Endocrinology and Metabolism, Turkey, 7GATA Department of Endocrinology and Metabolism, Turkey, 8GATA Department of Endocrinology and Metabolism, Turkey, 9GATA Department of Endocrinology and Metabolism, Turkey

Diabetes and cardiovascular

P392

ANTHROPOMETRIC DETERMINANTS OF ADIPONECTIN LEVELS IN OBESE AND NON OBESE PREMENOPAUSAL WOMEN

José Silva-Nunes1,2 , Léone Duarte1, Luísa Veiga2, Alice Melão2, Miguel Brito2, Fernando Malheiro11Endocrinology Department-Curry Cabral Hospital, Portugal, 2High School for the Health Technology of Lisbon, Portugal

Diabetes and cardiovascular

P393

Is brachial artery diameter most significant determinator of the flow -mediated dilatation?

Banu Kale Koroglu1 , Zeynep Dilek Aydin2, Sema Sezgin Goksu3, Mehmet Numan Tamer11Suleyman Demirel University Department of Endocrinology and Metabolism, Turkey, 2Suleyman Demirel University Department of Geriatry, Turkey, 3Suleyman Demirel University Department of Internal Medicine, Turkey

Diabetes and cardiovascular

P394

General and central obesity and risk of cardiovascular disease: results of the 7.6-year follow up study in Iranian men

Azadeh Zabetian1 , Farzad Hadaegh1, Fereidoun Azizi11Research Institute for Endocrine Science, Iran, Islamic Republic of

Diabetes and cardiovascular

P395

Prevalence of Undiagnosed Glucose Intolerance Changes According to Age and Gender in Japanese Middle Aged Working People

Hiroaki Kawano1 , Hirofumi Soejima1, Yasuhiro Nagayoshi1, Hiroshige Yamabe1, Yoshihiro Kinoshita1, Hisao Ogawa11Kumamoto Univ, Japan

Diabetes and cardiovascular

P396

Diabetes and obesity associated difference in aggregation platelet capacity.

Anastasiya Hlazkova1 , Natalya Yaroshevich1, Alieksey Romanovskiy1, Irina Melnik1, Valentina Pishik11Belarussian Medical Academy of Post-Graduate Education, Belarus

Diabetes and cardiovascular

P397

Functional balance in diabetic neuropathy

Tabassom Ghanavati1 , Mohammad jafar Shaterzadeh Yazdi1, Shahin Goharpey1, Ali asghar arastoo11Jondi-Shapour Medical Sciences University, Iran, Islamic Republic of

Diabetes and cardiovascular

P398

Terminalia bellerica (Belliric Myrobalan) stimulates the secretion and action of insulin and inhibits starch digestion and protein glycation

violet kasabri1 , peter flatt2, yasser abdelwahab21university of jordan, Jordan, 2university of ulster, United Kingdom

Diabetes and cardiovascular

P399

THE FREQUENCY OF DİABETİC RETİNOPATHY AND RELEVANT FACTORS FOR PREDİABETİC SUBJECTS

Erim Gulcan1 , Fatih Ozcura2, Sayime Aydin2, Esin Erbilen3, Lokman Koral11Dumlupinar University Faculty of Medicine, Department of Internal Medicine, Turkey, 2Dumlupinar Univesity Faculty of Medicine, Department of Ophtalmology, Turkey, 3Private Hekim Sinan Medicine Central, Ophtalmology, Turkey

Diabetes and cardiovascular

P400

Prognostic values of diabetic retinopathy progression for the assessment of lower limbs and heart muscle perfusion disturbances in patients with diabetes 2.

Tryniszewski Wieslaw1 , Gadzicki Mariusz1, Kusmierczyk Jaroslaw1, Gos Roman1, Rysz Jacek1, Maziarz Zbigniew11Medical University, Poland

Diabetes and cardiovascular

P401

ASSOCIATION BETWEEN INFLAMATION MARKERS AND METABOLIC PARAMETERS IN TYPE 2 DIABETIC PATIENTS, METABOLIC SYNDROME, IMPAIRED GLUCOSE TOLERANCE

Erdinc Ataman1 , Sebila Dokmetas1, Fatih Kilicli1, Fettah Acibucu11Cumhuriyet University, Faculty of Medicine, Department of Internal Medicine, Turkey, 2Cumhuriyet University, Faculty of Medicine, Department of Endocrinology, Turkey, 3Cumhuriyet University, Faculty of Medicine, Department of Endocrinology, Turkey, 4Cumhuriyet University, Faculty of Medicine, Department of Internal Medicine, Turkey

Diabetes and cardiovascular

P402

CRP level early after starting standard treatment of diabetic foot infection is associated with amputation risk

Baris Akinci1, Serkan Yener1, Sena Yesil1, Nur Yapar1, Yasin Kucukyavas1, Abdurrahman Comlekci1, Sevinc Eraslan1, Firat Bayraktar11Dokuz Eylul University, Turkey

Diabetes and cardiovascular

P403

Use of metformin in pregnancy: A survey of Turkish physicians’ attitudes

Baris Akinci1, Pinar Tosun1, Emine Bekci1, Serkan Yener1, Tevfik Demir1, Sena Yesil11Dokuz Eylul University, Turkey

Diabetes and cardiovascular

P404

Predictors of amputation in diabetic foot ulcer: Single centre experience in a large Turkish cohort

Sena Yesil1 , Baris Akinci1, Serkan Yener1, Firat Bayraktar1, Ozalp Karabay1, Hasan Havitcioglu1, Nur Yapar1, Atay Atabey1, Yasin Kucukyavas1, Abdurrahman Comlekci1, Sevinc Eraslan11Dokuz Eylul University, Turkey

Diabetes and cardiovascular

P405

The prevalence of anemia in Iranian type 2 diabetic patients and the role of nephropathy

SHOKOUFEH BONAKDARAN1 , Mohammad Vahedian1, mohammad Gharebaghi11medical sciences, Iran, Islamic Republic of

Diabetes and cardiovascular

P406

Frequency of hypogonadism in men with type 2 diabetes

Bahman Ghaderian1 , Mozhgan afkhamizadeh1, Reza rajabian1, Mohammad khajeh dalouei1, Hosein Ayatollahi1, sahar Ghareh11Mashhad university of medical science, Iran, Islamic Republic of

Diabetes and cardiovascular

P407

IS TESTOSTERONE THERAPY SAFE FOR CARDIOVASCULAR SYSTEM? THE IMPACT OF CARDIAC ULTRASOUND MONITORING.

Marina Uryadnova1 , Svetlana Kalinchenko2, Yuliya Tishova3, George Mskhalaya3, Leonid Vorslov3, Farid Saad41City Clinical Hospital No.81, Center of Clinical Diagnostics No.7, Russian Federation, 2Chair of the Clinical Andrology, Medical Faculty, PFUR, Russian Federation, 3Research Center for Endocrinology, Russian Federation, 4Bayer Schering Pharma, Dpt. of Men’s Healthcare, and Gulf Medical University School of Medicine, United Arab Emirates

Diabetes and cardiovascular

P408

Effects of Alteration in Serum Testosterone Levels on Beta Cell Functions in Male Patients with Hypogonadism and in Female Patients with Polycystic Ovary Syndrome

Gökhan Üçkaya1 , S. Erol Bolu1, Taner Özgürtas2, M. Kemal Erbil2, Mustafa Kutlu11Dept. of Endocrinology and Metabolism, Gülhane School of Medicine, Turkey, 2Dept. of Biochemistry and Clinical Biochemistry, Gülhane School of Medicine, Turkey

Diabetes and cardiovascular

P409

Endothelium Dependent Hemostatic Factors and Subclinical Inflammation in Women with Previous Gestational Diabetes Mellitus

Tevfik Demir1 , Sevinc Biberoglu Eraslan1, Serkan Yener1, Baris Akinci1, Mehmet Ali Özcan11Department of Endocrinology and Metabolism, Dokuz Eylul University, School of Medicine,, Turkey

Diabetes and cardiovascular

P410

METABOLIC SYNDROME AND MEAL STIMULATED C-PEPTIDE LEVELS AS USEFUL CLINICAL MARKERS IN CHOOSING METFORMIN FOR COMBINATION THERAPY WITH SULPHONYLUREA IN TYPE 2 DIABETIC SUBJECTS

Branka Koprivica1 , Teodora Beljic Zivkovic21Special Hospital Stari Slankamen, Serbia, 2Department Of Endocrinology, Zvezdara University Medical Centre, Serbia

Diabetes and cardiovascular

P411

ANALYSIS OF THE EFFECTIVENESS AND SECURITY OF THE INSULINIZATION IN A DAILY DIABETES HOSPITAL

Cristobal Morales1 , Juan M Garcia-Quiros1, Monica Tome1, Ignacio Fernandez1, Isabel Serrano1, Guillermo Martinez de Pinillos1, Angel Sendon11Virgen Macarena Hospital, Spain

Diabetes and cardiovascular

P412

CLINICAL CHARACTERISTICS AND MOTHER-FETAL RESULTS IN PATIENTS WITH GESTATIONAL DIABETES

Cristobal Morales1 , Guillermo Martinez de Pinillos1, Juan M Garcia-Quiros1, Monica Tome1, Ignacio Fernandez1, Isabel Serrano1, Angel Sendon11Virgen Macarena Hosputal, Spain

Diabetes and cardiovascular

P413

Quality of life in Diabetes Mellitus: conditional issues of treatment and coping strategies.

Miguel Pereira1 , Celestino Neves1,2, João Pereira3, Eduardo Carqueja1, Marta Alves1, Davide Carvalho1,2, Rui Coelho1,2, José Medina1,21Hospital S. João, Portugal, 2University of Porto, Portugal, 3Maia's Superior Institute, Portugal

Diabetes and cardiovascular

P414

THYROID DYSFUNCTIONS AND SERUM CREATINE KINASE LEVELS IN STATINS-USING PATIENTS WITH HYPERLIPIDEMIA

Taner Bayraktaroglu1,4 , Mesut Ozkaya2, Faruk Kutluturk3,4, Adil Dogan Azezli4, Yusuf Orhan41Zonguldak Karaelmas University, Faculty of Medicine, Endocrinology and Metabolism, Turkey, 2Sutcuimam University, Faculty of Medicine, Endocrinology and Metabolism, Turkey, 3Gaziosmanpasa University, Faculty of Medicine, Endocrinology and Metabolism, Turkey, 4Istanbul University, Istanbul Faculty of Medicine, Endocrinology and Metabolism, Turkey

Diabetes and cardiovascular

P415

HISTOPATOLOGICAL EFFECTS OF STRESS ON THE HEART MUSCLE IN RATS

TUBA DEMIRCI1 , ELVAN ÖZBEK11ATATÜRK UNIVERSITY MEDICAL SCHOOL DEPARTMENT OF HISTOLOGY AND EMBRYLOGY, Turkey

Diabetes and cardiovascular

P416

Insulin casts in type 2 patients different shadows with proliferate retinopathy and those with Stent or Bypass on Coronary Arteries

Dragan Tesic1 , Pavle Pantelinac1, Milena Mitrovic1, Bojan Vukovic11Clinic of Endocrinology, Diabetes and Metabolic Diswases, Serbia

Diabetes and cardiovascular

P417

Evaluation of the severity of hepatic steatosis in type 2 diabetes.

Leila Ben Salem Hachmi, Leila Ben Farhat2, Ridha Waghlani1, Chiraz Bouzid1, Lotfi Hendaoui2, Claude Ben Slama11National institut of nutrition, Tunisia, 2Mongi Slim Hospital, Tunisia

Diabetes and cardiovascular

P418

Microalbuminuria and cardiovascular risk in diabetic patients.

Ergita Nelaj1 , Margarita Gjata1, Mihal Tase11UHC "Mother Teresa", Albania

Diabetes and cardiovascular

P419

Type 2 diabetes mellitus: Failure to recognize cardiovascular risk jeopardizes prevention of diabetes complications in type 2 diabetic patients in daily practice

Eckart Jungmann1 , Gisela Jungmann11St. Vincent's Hospital, Germany

Diabetes and cardiovascular

P420

Prevalence of diabetic retinopathy and its relation with other risk factors.

Ergita Nelaj1 , Margarita Gjata1, Ilda Lilaj1, Orledia Bare1, Edite Sadiku1, Ledio Collaku1, Jola Klosi1, Mihal Tase11Dept of Internal Medicine, UHC "Mother Teresa", Albania

Diabetes and cardiovascular

P421

Screening of the Romani population in Serbia for diabetes

Teodora Beljic Zivkovic, Rodoljub Zivkovic2, Toma Ignjatovic2, Milica Marjanovic1, Ivan Soldatovic2, Stela Prgomelja2, Branka Koprivica3, Dragoljub Ackovic41¹Zvezdara University Medical Center, Divison of Endocrinology, Serbia, 2² Diabetes Association of Serbia,, Serbia, 3³ Special Hospital Stari Slankamen, Serbia, 44Roma Community Centar «8 April», Serbia

Diabetes and cardiovascular

P422

Thyrotropin and thyroxine are associated with fasting insulin and insulin resistance in euthyroid impaired glucose tolerant subjects

Tasnim Farasat1 , Abdul Majeed Cheema1, M. Naeem Khan11Lahore College for Women University, Lahore, Pakistan, 2Faculty of Biotechnology & Informatics, Balochistan University of I.T., Engineering & Management Sciences, Quetta, Pakistan, 3Registrar & Professor, Zoology Department, University of the Punjab, Lahore, Pakistan

Diabetes and cardiovascular

P423

The effects of Urtica Diocia on rat pancreatic β cell

Majid Mobasseri1 , Akbar Aliasgarzadeh1, Amir Bahrami1, Mitra Niafar1, Frrzad Najafipoor1, Nosratollah Zargami11Tabriz University (Medical Sciences), Iran, Islamic Republic of

Diabetes and cardiovascular

P424

Urtica Diocia effects on glucose utilization by human muscle cells

Majid Mobasseri1 , Akbar Aliasgarzadeh1, Naser Aghamohammadzadeh1, Nosratollah Zargami1, Amir Bahrami11Tabriz University (Medical Sciences), Iran, Islamic Republic of

Diabetes and cardiovascular

P425

Effects of oral contraceptives versus no treatment on glucose tolerance and patients’ satisfaction during long time follow up in 69 hirsute patients

Magdalene Andries1 , Dorte Glintborg1, Marianne Andersen11Department of Endocrinology, Odense University Hospital, Denmark

Diabetes and cardiovascular

P426

The effect of creatinine clearance on the short term outcome of neuropathic diabetic foot ulcers

Baris Akinci1, Sena Yesil1, Firat Bayraktar1, Yasin Kucukyavas1, Serkan Yener1, Abdurrahman Comlekci1, Sevinc Eraslan11Dokuz Eylul University, Turkey

Diabetes and cardiovascular

P427

Mean platelet volume in women with previous gestational diabetes and its alteration during pregnancy

Aygul Celtik1, Baris Akinci1, Tevfik Demir1, Serkan Yener1, Sena Yesil11Dokuz Eylul University, Turkey

Diabetes and cardiovascular

P428

Reduction of Major Amputations after Starting a Multidisciplinary Diabetic Foot Care Team: Single centre experience from Turkey

Sena Yesil1 , Baris Akinci1, Firat Bayraktar1, Hasan Havitcioglu1, Ozalp Karabay1, Nur Yapar1, Cenk Demirdover1, Serkan Yener1, Muhittin Yalcin1, Abdurrahman Comlekci1, Sevinc Eraslan11Dokuz Eylul University, Turkey

Diabetes and cardiovascular

P429

Prediction of developing metabolic syndrome after gestational diabetes mellitus

Baris Akinci1, Aygul Celtik1, Serkan Yener1, Sena Yesil11Dokuz Eylul University, Turkey

Diabetes and cardiovascular

P430

EXERCISE INDUCED OXIDATIVE STRESS IN TYPE 2 DIABETES: RELATION TO DIASTOLIC DYSFUNCTION AND HYPERTENSION

Nada Kostic11Clinical Hospital Center Dr Dragisa Misovic, Clinic for Internal Medicine, School of medicine, Univerisity of Belgrade, Serbia

Diabetes and cardiovascular

P431

serum homocysteine levels in diabetes and its relationship to nephropathy

Mozhgan Afkhamizadeh1 , Hosein Ayatollahi1, Majid Abrishami1, Zohreh Musavi1, Shokufeh Bonakdaran1, Robab Aboutorabi1, Mohammad Khajeh dalouei11mashhad university of medical science, Iran, Islamic Republic of

Diabetes and cardiovascular

P432

CAN TESTOSTERONE THERAPY BE INCLUDED INTO DIABETES TREATMENT IN MEN WITH METABOLIC SYNDROME (MS) AND HYPOGONADISM?

Svetlana Kalinchenko1 , Farid Saad2, George Mskhalaya3, Yuliya Tishova31PFUR, Medical faculty, Chair of Clinical Andrology, Russian Federation, 2Bayer Schering Pharma, Dpt. of Men’s Healthcare, and Gulf Medical University School of Medicine, United Arab Emirates, 3Research Center for Endocrinology, Russian Federation

Diabetes and cardiovascular

P433

THE EFFECT OF TELMISARTAN AND IRBESARTAN TREATMENTS ON INSULIN RESISTANCE OF PATIENTS WITH TYPE 2 DIABETES AND HYPERTENSION

Babürsah Tasli1, Özen Öz Gül1, Ercan Tuncel1, Metin Güclü1, Sinem Kiyici1, Sazi Imamoglu11Endocrinology and Metabolism Department, Uludag University, Faculty of Medicine, Turkey

Diabetes and cardiovascular

P434

INSULIN TREATMENT INTENSIFICATION IN DAILY DIABETES HOSPITAL

Juan M Garcia-Quiros1 , Cristobal Morales1, Isabel Serrano1, Guillermo Martinez de Pinillos1, Monica Tome1, Ignacio Fernandez1, Angel Sendon11Virgen Macarena Hospital, Spain

Diabetes and cardiovascular

P435

WELFARE ACTIVITY IN DAY DIABETES HOSPITAL IN OUR AREA: OUR EXPERIENCE IN 2007.

Isabel Serrano1 , Cristobal Morales1, Juan M Garcia-Quiros1, Guillermo Fernandez1, Monica Tome1, Ignacio Fernandez1, Angel Sendon11Virgen Macarena Hospital, Spain

Obesity and Metabolism

P436

ASSOCIATION BETWEEN VISCERAL FAT AND CARDIOVASCULAR DISEASE RISK FACTORS

DILEK BERKER1 , YUSUF AYDIN1, SERHAT ISIK1, YASEMIN TUTUNCU1, LALE PASAOGLU2, TUNCAY DELIBASI1, SERDAR GULER11S.B. ANKARA NUMUNE RESEARCH AND TRAINING HOSPITAL, ENDOCRINOLOGY AND METABOLISM CLINIC, Turkey, 2S.B. ANKARA NUMUNE RESEARCH AND TRAINING HOSPITAL, RADIOLOGY DEPARTMENT, Turkey

Obesity and Metabolism

P437

SEVERE HYPERTRIGLYCERIDEMIA AND TRIGLYCERIDE APHERESIS

Taner Bayraktaroglu1,3 , Mesut Ozkaya2, Faruk Kutluturk3, Adil Dogan Azezli4, Yusuf Orhan41Zonguldak Karaelmas University, Faculty of Medicine, Endocrinology and Metabolism, Turkey, 2Sutcu Imam University, Medical Faculty, Endocrinology and Metabolism, Turkey, 3Gaziosmanpasa University, Medical Faculty, Endocrinology and Metabolism, Turkey, 4Istanbul University, Istanbul Faculty of Medicine, Endocrinology and Metabolism, Turkey

Obesity and Metabolism

P438

Lower dietary acid load is related to a lower incidence of the metabolic syndrome

Mònica Bulló1 , Nancy Babio1, Jordi Salas-Salvadó11Rovira i Virgily University, Spain

Obesity and Metabolism

P439

THE EVALUATION OF METABOLIC EFFECTS FOLLOWING GHRELIN AND SALBUTAMOL ADMINISTRATION

Andrea Benso1, David H. St-Pierre1, Elena Gramaglia1, Fabrizio Riganti1, Barbara Lucatello1, Ilaria Olivetti1, Ezio Ghigo1, Fabio Broglio11University of Turin, Italy

Obesity and Metabolism

P440

TNFR-1 knockout protects against diet induced obesity

Talita Romanatto1 , Erika A Roman1, Rapahel G Denis1, Ana Paula Arruda1, Marciane Milanski1, Giovanna Degasperi1, Carina Sólon1, Lício A Velloso11State University of Campinas, Brazil

Obesity and Metabolism

P441

ACUTE INFLAMMATORY BIOMARKER MODIFICATIONS AS A RESULT OF A SINGLE SESSION OF SUBMAXIMAL EXERCISES IN OBESE SUBJECTS.

Zorica Caparevic11Clinical Hospital Center Dr Dragisa Misovic, Clinic for Internal Medicine, School of Medicine, Univerisity of Belgrade, Serbia

Obesity and Metabolism

P442

Adipokines’ variations due to a lower caloric intake in endocrine obese patients associating the metabolic syndrome S.Oros1, O.Ianaş2, L.Lerescu3, A.Sălăgeanu3, M.Giurcăneanu2, S.Vlădoiu2, A.Dragomir1, I.Gherlan1,2, L.Iconaru1,2, R.Hristea1, Constantin Dumitrache1,2 1. Carol Davila University of Medicine and Pharmacy, Bucharest 2. C.I.Parhon National Institute of Endocrinology, Bucharest 3. I. Cantacuzino National Institute for Research-Development in Mycrobiology and Immunology, Bucharest

Sabina Oros1 , Olga Ianas2, Liviu Lerescu3, Aurora Salageanu3, Mihaela Giurcaneanu2, Suzana Vladoiu2, Adina Dragomir1, Iuliana Gherlan1,2, Laura Iconaru1,2, Ruxandra Hristea1, Constantin Dumitrache1,21Carol Davila University of Medicine and Pharmacy, Romania, 2C.I.Parhon National Institute of Endocrinology, Romania, 3I. Cantacuzino National Institute for Research-Development in Mycrobiology and Immunology, Romania

Obesity and Metabolism

P443

Influence of metformin on carbohydrate metabolism in young women with metabolic syndrome.

Justyna Kuliczkowska-Plaksej, Grazyna Bednarek-Tupikowska1, Alicja Filus1, Anna Trzmiel-Bira1, Wlodzimierz Bednorz1, Andrzej Milewicz11Department of Endocrinology, Diabetology and Isotope Therapy, Medical University Wroclaw, Poland, Poland

Obesity and Metabolism

P444

Letrozole normalizes serum testosterone and reduces body weight in morbidly obese men with obesity-related hypogonadotropic hypogonadism

Sandra Loves1 , Jos de Jong1, Adriaan van Sorge1, Darryl Telting1, Hans de Boer11Rijnstate Hospital, Netherlands

Obesity and Metabolism

P445

Effect of Metformine Treatment on Serum Paraoxonase and Oxidative Status in Obese Women

Semin Fenkci1 , Nedim Karagenc2, Fulya Akin31Pamukkale University, School of Medicine, Department of Internal Medicine, Turkey, 2Pamukkale University, School of Medicine, Department of Medical Biology, Turkey, 3Pamukkale University, School of Medicine, Department of Endocrinology and Metabolism, Turkey

Obesity and Metabolism

P446

Serum visfatin concentration in obesity and impaired glucose tolerance - relationship with insulin resistance, blood pressure and proinflammatory factors

Irina Kowalska1 , Marek Straczkowski1, Agnieszka Nikolajuk1, Monika Karczewska- Kupczewska1, Agnieszka Adamska1, Maria Gorska11Medical University of Bialystok, Department of Endocrinology, Diabetology and Internal Medicine, Poland

Obesity and Metabolism

P447

Intracerebroventricular leptin increase AKT phosphorylation stimulated by insulin in skeletal muscle: the role of adrenergic signal and JAK2 activation.

Erika Anne Roman1 , Daniel Reis2, Talita Romanatto1, Denis Maimoni2, Carina Solon1, Joseane Morari1, Lício Augusto Velloso1, Márcio Alberto Torsoni21State University of campinas, Brazil, 2Braz Cubas University, Brazil

Obesity and Metabolism

P448

CANNABINOIDS AND REGULATION OF ADIPOGENESIS IN DIFFERENTIATING 3T3-L1 PREADIPOCYTES

Andrea M Isidori1 , Francesca Lolli1, Silvia Pierotti1, Carlotta Pozza1, Vincenzo Bonifacio1, Loredana Gandini1, Andrea Lenzi11'Sapienza' University of Rome, Italy

Obesity and Metabolism

P449

Metabolic syndrome highly correlates to non toxic multinodular goiter progression: iperinsulinism a way to growth

Roberto Citarrella1 , Francesco Chiofalo1, Calogero Vetro1, Alessio Lo Coco1, Luciana Puleo11Endocrinology section of Universitary Policlinic, Italy

Obesity and Metabolism

P450

IGF-1 GENE POLYMORPHISM IN OBESE PATIENTS WITH INSULIN RESISTANCE

Güzin Fidan Yaylali1 , Fulya Akin1, Sabahat Turgut1, Raziye Kursunluoglu11Pamukkale University, Turkey

Obesity and Metabolism

P451

Familial obesity and the role of nutrition

Maryam Beheshti Zavareh 1, Saeid Sadeghian1, Parvin Mirmiran1, Firoozeh Hosseini11Research institute for Endocrine Sciences, Shahid Beheshti University of Medical Siences, Iran, Islamic Republic of

Obesity and Metabolism

P452

Adiponectin and vascular properties in obese patients. Is it a novel biomarker of early atherosclerosis?

Ninel Wolfson1, Yffat Goldberg1, Marina Shargorodsky11wolfson medical center, Israel

Obesity and Metabolism

P453

A Comparison of Serum Leptin Levels and Metabolic Parameters Included Serum Lipoproteins and Glucose Homeostasis between National Wrestlers and Healthy Males

Faruk Yamaner1, Taner Bayraktaroglu2, Hulusi Atmaca2, Mehmet Akif Ziyagil3, Kemal Tamer41School of Physical Education and Sports, Zonguldak Karaelmas University, Turkey, 2Endocrinology and Metabolism, Faculty of Medicine, Zonguldak Karaelmas University, Turkey, 3Deparment of Physical Education and Sports, Amasya University, Turkey, 4School of Physical Education and Sports, Gazi University, Turkey

Obesity and Metabolism

P454

Impact of protein content of low-carbohydrate/high-fat diets upon ketosis, energy expenditure and glucose utilization in rats

Max Bielohuby1 , Ellen Kienzle2, Matthias H. Tschöp3, Andreas Hoeflich4, Martin Bidlingmaier11Neuroendocrine Unit, Medizinische Klinik - Innenstadt, LMU, Germany, 2Institute of Physiology, Biochemistry, and Animal Nutrition, LMU, Germany, 3Obesity Research Center, Dept. of Psychiatry, University of Cincinnati, United States, 4Laboratory of Mouse Genetics, Research Unit Genetics and Biometry - FBN, Germany

Obesity and Metabolism

P455

ΤΗΥROID FUNCTION TESTS (TFTS), MEASURES OF ADIPOSITY AND METABOLIC SYNDROME IN APPARENTLY HEALTHY EUTHYROID INDIVIDUALS

Katerina Saltiki1,2 , Kimon Stamatelopoulos3, Paraskevi Voidonikola3, Emily Mantzou1, Christos Papamichael3, Maria Alevizaki1,21Endocrine Unit, Evgenidion Hospital, Athens University School of Medicine, Greece, 2Endocrine Unit, Dept Medical Therapeutics, Alexandra Hospital, Athens University School of Medicine, Greece, 3Vascular Laboratory, Dept of Medical Therapeutics, Alexandra Hospital, Athens University School of Medicine, Greece

Obesity and Metabolism

P456

25-Hydroxyvitamin D is associated with insulin resistance, obesity, and serum lipids in polycystic ovary syndrome

Elisabeth Wehr1 , Stefan Pilz1, Natascha Schweighofer1, Albrecht Giuliani1, Daisy Kopera1, Thomas R. Pieber1, Barbara Obermayer-Pietsch11Medical University Graz, Austria

Obesity and Metabolism

P457

CHRONIC RENAL DISEASE, HYPERFILTRATION, METABOLIC SYNDROME AND HYPOGONADISM: IS THERE A LINK?

Yuliya Tishova1 , Svetlana Kalinchenko2, Maria Novikova3, Evgeniy Shilov3, Vladimir Borisov3, Farid Saad41Research Center for Endocrinology, Russian Federation, 2Chair of the Clinical Andrology, Medical Faculty, PFUR, Russian Federation, 3I.M. Sechenov Moscow Medical Academy, Russian Federation, 4Bayer Schering Pharma, Dpt. of Men’s Healthcare, and Gulf Medical University School of Medicine, United Arab Emirates

Obesity and Metabolism

P458

Changes in serum levels of Fetal Antigen 1 (FA1/pref-1/Dlk1) in extreme nutritional states

Alin Andries1 , René Støving1, Andrea Wolf2, U. Beisiegel3, Kirsten Hørder1, S.B. Martin1, B.M. Abdallah1, Moustapha Kassem11Department of Endocrinology, Odense University Hospital, Denmark, 2Department for Visceral and Transplantation Surgery, University Hospital Ulm, Germany, 3Institute for Molecular Cell Biology, Center for Experimental Medicine, University Hospital Hamburg Eppendorf, Germany

Obesity and Metabolism

P459

Influence of metformin on selected lipids and apolipoproteins concentrations in young women with metabolic syndrome.

Justyna Kuliczkowska-Plaksej, Grazyna Bednarek-Tupikowska1, Alicja Filus1, Anna Trzmiel-Bira1, Andrzej Milewicz11Department of Endocrinology, Diabetology and Isotope Therapy, Medical University Wroclaw, Poland, Poland

Obesity and Metabolism

P460

Correlation of Leptin, Total Body Fat Mass and Body Fat distribution in overweight postmenopausal women

Nino Dolidze1, Ellen Giorgadze1, Ketevan Asatiani1, Marina Tsagareli1, Marina Lomidze1, Arkadi Surmava1, Ketevan Bochorishvili11N4 Clinical Hospital, Ltd Healthy Life, Georgia

Obesity and Metabolism

P461

Diabetic patient with abnormal LFTS

Gideon Mlawa1 , Charles Bodmer2, Raymond D'Souza3, Robert Skelly41Colchester General Hospital, United Kingdom, 2Colchester Hospital, United Kingdom, 3ChaseFarm Hospital, United Kingdom, 4Colchester Hospital, United Kingdom

Obesity and Metabolism

P462

Impact of growth hormone receptor blockade on Substrate Metabolism during Short-Term Fasting in Healthy Subjects

Louise Moller1 , Helene Norrelund2, Jan Frystyk1, Niels Moller1, Jens OL Jorgensen11Medical Department M (Endocrinology and Diabetes), Denmark, 2Department of Internal Medicine, Denmark

Obesity and Metabolism

P463

Are hypothalamic oscillators dysfunctional with high fat feeding?

Sara Namvar1 , Amie Gyte2, Susan Birtles2, John Myatt2, Brendan Leighton1, Hugh Piggins11The University of Manchester, United Kingdom, 2AstraZeneca, United Kingdom

Obesity and Metabolism

P464

Glucose-dependent insulinotropic polypeptide (GIP) increases glucose-uptake in muscle- and adipocyte cells in-vitro

Janin Andres1 , Katrin Biedasek1, Özlem Goegebakan1, Knut Mai1, Andreas Pfeiffer1, Joachim Spranger11Charité - CBF, Germany

Obesity and Metabolism

P465

Glucose-dependent insulinotropic polypeptide (GIP) modulates inflammatory markers in adipose tissue

Özlem Gögebakan1 , Martin Osterhoff1, Sandy Mosig3, Ines Middelbeck1, Natalia Rudovich2, Rita Schüler1, A.F.H. Pfeiffer1,21German Institute of Human Nutrition (DIfE), Germany, 2Endocrinology, Diabetes and Nutrition, Charité- University Medicine Berlin, Campus Benjamin Franklin, Germany, 3Friedrich-Schiller-University Medicine, Institute for Vascular Medicine, Germany

Obesity and Metabolism

P466

Glucose RapidSpray™ as Adjuvant in Diet Restriction Programmes

Yeganeh Manon Khazrai1 , Fabio Cacciapaglia1, Maria Altomare2, Sergio Leotta2, Paolo Pozzilli11Depart. Endocrinology and Diabetes, University Campus Bio-Medico, Italy, 2Sandro Pertini Hospital, Italy

Obesity and Metabolism

P467

Plasma monocyte chemoattractant protein-1 and macrophage inflammatory protein-1alpha are increased in patients with polycystic ovary syndrome and associated with adiposity, but unaffected by pioglitazone treatment.

Dorte Glintborg1 , Marianne Andersen1, Bjørn Richelsen2, Jens Bruun21Department of Endocrinology, Odense University Hospital, Denmark, 2Department of Endocrinology and Metabolism C, Aarhus University Hospital, Aarhus Sygehus, Denmark

Obesity and Metabolism

P468

ELEVATED PROLACTIN SERUM LEVEL IN ERECTILE DYSFUNCTION CASES CAN BE PREDICT BY METABOLIC SYNDROME

Vasile Coca1 , Mariana Cecilia Coca11Diabetes Clinical Center, Romania

Obesity and Metabolism

P469

SEXUAL DYSFUNCTION IN WOMEN WITH OBESITY

Güzin Fidan Yaylali1 , Selma Tekekoglu1, Fulya Akin11Pamukkale University, Turkey

Obesity and Metabolism

P470

Effects of green tea consumption on blood pressure, total cholesterol, body weight and fat in healthy volunteers

Emad Al-Dujaili1 , Jon-Paul Bradley1, Suzana Almoosawi1, Lorna Fyfe11Queen Margaret University, United Kingdom

Obesity and Metabolism

P471

Subcutaneous Adipose Tissue Topography and Metabolic Disturbances in Polycystic Ovary Syndrome

Elisabeth Wehr1 , Reinhard Möller1, Renate Horejsi1, Albrecht Giuliani1, Daisy Kopera1, Natascha Schweighofer1, Thomas R. Pieber1, Barbara Obermayer-Pietsch11Medical University Graz, Austria

Obesity and Metabolism

P472

Melanocortin-4-Receptor Gene Variants: Hotspot or Identical by Descent?

Jessica Grothe1 , Harald Brumm1, André Scherag4, Susann Friedel3, Anke Hinney3, Johannes Hebebrand3, Thomas Illig2, Harald Grallert2, Susanna Wiegand1, Heiko Krude1, Sadaf Farooqi5, Annette Grüters1, Heike Biebermann11Institute of Experimental Pediatric Endocrinology, Charité Campus Virchow- Klinikum, Germany, 2Helmholtz Zentrum München - German Research Center for Environmental Health, Institute of Epidemiology, Germany, 3Department of Child and Adolescent Psychiatry, Rheinische Kliniken Essen, University of Duisburg-Essen, Germany, 4Institut für Medizinische Informatik, Biometrie und Epidemiologie Universitätsklinikum Essen, Germany, 5University of Cambridge Metabolic Research Laboratories, Addenbrooke's Hospital, United Kingdom

Obesity and Metabolism

P473

ASSOCIATION BETWEEN PLATELET COUNT AND METABOLIC RISK FACTORS IN OVER WEIGHT AND OBESE WOMEN

FARUK KUTLUTURK1 , SINAN TANYOLAC2, ADIL AZEZLI2, YUSUF ORHAN21Gaziosmanpasa University, Faculty of Medicine, Division of Endocrinology and Metabolism, Turkey, 2Istanbul University, Istanbul Faculty of Medicine, Division of Endocrinology and Metabolism, Turkey

Obesity and Metabolism

P474

THE EVALUATION OF THE OXIDATIVE STRESS IN OBESE ADOLESCENT GIRLS WITH FULL OR PARTIAL METABOLIC SYNDROME

Ioannis Karamouzis1 , Christina Kanaka-Gantenbein1, Panagiota I. Pervanidou1, Maria-Alexandra Magiakou1, Anna-Betina Haidich2, Sofia Sakka1, Ioannis Papasotiriou1, George P. Chrousos11Department of Endocrinology, Diabetes and Metabolism, First Pediatric Clinic, University of Athens, Greece, 2Laboratory of Hygiene, Faculty Medicine, Aristotle University of Thessaloniki, Greece

Obesity and Metabolism

P475

The role of family and parental factors in childhood obesity.

Anjelika Solntsava1, Mariya Vishnevskaya11Belarusian State Medical University, Belarus

Obesity and Metabolism

P476

RELATIONSHIP OF SERUM GAMMA-GLUTAMYLTRANSFERASE AND ADIPOSITY MEASURES WITH C- REACTIVE PROTEIN IN SEVERE OBESE WOMEN

Mirjana Sumarac-Dumanovic, Dragan Micic1, Danica Stamenkovic-Pejkovic1, Goran Cvijovic1, Danka Jeremic1, Aleksandra Kendereski11Institute of Endocrinology, Diabetes and Diseases of Metabolism, Seychelles

Obesity and Metabolism

P477

A Retrospective Analysis of the Relationship between Thyroid Function and Obesity in a Single Center Obesity Outpatient Policlinic

Özen Öz Gül1 , Canan Ersoy1, Bülent Gül2, Metin Güclü1, Mahmut Ibanoglu2, Sengül Cangür3, Sinem Kiyici1, Soner Cander1, Oguz Kaan Ünal1, Erdinc Ertürk1, Ercan Tuncel1, Sazi Imamoglu11Endocrinology and Metabolism Department, Uludag University, Faculty of Medicine, Turkey, 2Internal Medicine, Uludag University, Faculty of Medicine, Turkey, 3Biostatistics, Uludag University, Faculty of Medicine, Turkey

Obesity and Metabolism

P478

RELATIONSHIP BETWEEN PREHYPERTENSION AND METABOLIC RISK MARKERS IN OVER WEIGHT AND OBESE WOMEN

FARUK KUTLUTURK1 , TANER BAYRAKTAROGLU2, ADIL AZEZLI2, YUSUF ORHAN21Gaziosmanpasa University, Faculty of Medicine, Division of Endocrinology and Metabolism, Turkey, 2Istanbul University, Istanbul Faculty of Medicine, Division of Endocrinology and Metabolism, Turkey

Obesity and Metabolism

P479

Short term elevation of estradiol concentrations does not affect hepatic VLDL-TG production

Lars C. Gormsen1 , Christian Host1, Claus Gravholt1, Jens S. Christiansen1, Soren Nielsen11Aarhus University Hospital, Denmark

Obesity and Metabolism

P480

Serum Adiponectin Levels and Polymorphism of CB1 Endocannabinoid Receptor (A3813G, A4895G, G1422A) in Postmenopausal Women

Diana Jedrzejuk1 , Felicja Lwow2, Katarzyna Dunajska2, Lukasz Laczmanski1, Andrzej Milewicz11Wroclaw University of Medicine, Poland, 2University School of Physical Education, Wroclaw, Poland

Obesity and Metabolism

P481

Relationships of TNFα system with glucose and lipid oxidation in subjects with different degree of insulin sensitivity

Agnieszka Adamska1 , Monika Karczewska-Kupczewska1, Irina Kowalska1, Agnieszka Nikolajuk1, Maria Górska1, Marek Straczkowski11Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, Poland

Obesity and Metabolism

P482

Variation of daytime melatonin levels

Beata Racz1 , Karel Vondra1, Michaela Duskova1, Katerina Simunkova1, Martin Hill1, Luboslav Starka11Institute of Endocrinology, Czech Republic

Obesity and Metabolism

P483

Aromatase expression in peripheral blood leukocytes from adult and elderly female and male subjects.

Elisa Pignatti1 , Alessandra Rossi1, Sara Scaltriti1, Erica Taliani1, Vincenzo Rochira1, Manuela Simoni1, Cesare Carani11Integrated Department of Medicine, Endocrinology and Metabolism, and Geriatrics, University of Modena and Reggio Emilia, Italy

Obesity and Metabolism

P484

Non-diabetic Metabolic Syndrome and Obesity do not affect Serum Paraoxonase-1, HDL-Paraoxonase and arylestherase activities but affects oxidative stress and inflamation

Suzan Tabur1 , Ayse Nur Torun1, Tevfik Sabuncu1, Mehmet Nuri Turan1, Ali Riza Ocak2, Hakim Celik21Harran University, Faculty of Medicine, Department of Endocrinology, Turkey, 2Harran University, Faculty of Medicine, Department of, Turkey

Obesity and Metabolism

P485

Carotid IMT values are related to insulin resistance and visceral disposition of adiposity in obese patients

Anca Sirbu1,2 , Horia Nicolae1,2, Tudor Arbanas1,2, Serban Gologan1,2, Carmen Barbu1,2, Aura Reghina1,2, Claudia Lenghen2, Simona Fica1,21Carol Davila University of Medicine and Pharmacy, Romania, 2Elias University Hospital, Romania

Obesity and Metabolism

P486

The effect of weight loss on serum mannose binding lectin (MBL) levels

Pernille H. Hoeyem1 , Jens M. Bruun2, Steen B. Pedersen2, Bjoern Richelsen2, Jens S. Christiansen1, Troels K. Hansen11Immunoendocrine Research Unit and Medical Department M, Aarhus University Hospital, Denmark, 2Department of Endocrinology and Metabolism C, Aarhus University Hospital, Denmark

Obesity and Metabolism

P487

INSULIN RESİSTANCE AND ANEMİA MARKERS

Süheyla Görar1 , Cavit Çulha1, Y.Selim Demir1, Rüstü Serter1, Yalcin Aral11Endocrinology and Metabolic Disease Department, Ankara Education and Research Hospital, Turkey

Obesity and Metabolism

P488

Vasomotor dysfunction and alterations of adipokines in metabolic syndrome patients with insulin resistance

Peteris Tretjakovs1,2 , Antra Jurka1,2, Inga Bormane1,2, Dace Reihmane1, Indra Mikelsone1, Liga Balode1, Juris Aivars1, Valdis Pirags1,21University of Latvia, Latvia, 2Pauls Stradins Cinical University Hospital, Latvia

Obesity and Metabolism

P489

Effect of pharmaceutical intervention on serum levels of Advanced Glycated End products in women with Polycystic Ovary Syndrome

Evanthia Diamanti-Kandarakis 1,2 >, Charikleia Christakou1,2, Chistina Piperi2, Eleni Kandaraki1,2, Ilias Katsikis3, Christos Adamopoulos2, Athanasios G Papavasiliou2, Dimitrios Panidis31Endocrine Section,First Department of Internal Medicine,Laiko Hospital, Greece, 2Laboratory of Biological Chemistry, University of Athens Medical School, Greece, 3Division of Endocrinology & Human Reproduction, Second Department of Obstetrics & Gynaecology, Medical School, Aristotle University of Thessaloniki, Greece

Obesity and Metabolism

P490

Insulin-resistance and abnormal glycaemia characterize the metabolic syndrome of polycystic ovary syndrome but not of matched controls

Serban Radian1,2 , Valentina Raluca Mihaila1, Ileana Botusan1, Nicoleta Baculescu1, Monica Gheorghiu1,2, Simona Fica1, Florin Grigorescu3, Mihail Coculescu1,21C. Davila University of Medicine, Romania, 2Institute of Endocrinology, Romania, 3Molecular Endocrinology Laboratory, IURC, Montpellier 1 University, France

Obesity and Metabolism

P491

Regulation of novel metabolic regulator fibroblast growth factor-21 by body adiposity and hypercortisolemia: studies in patients with obesity and Cushing’s syndrome

Viktoria Durovcova1 , Michal Krsek1, Vaclav Hana1, Josef Marek1, Marketa Bartlova1, Petra Kavalkova1, Martin Haluzik113rd Department of Internal Medicine, 1st Faculty of Medicine, Charles University, Czech Republic

Obesity and Metabolism

P492

THE INFLUENCE OF WEIGHT LOSE ON IMMUNE SYSTEM

Mahmut YAZICI1,2 , Deniz Engin GOK1, Aysel PEKEL2, Serkan TAPAN3, Yusuf Alper SONMEZ1, Ugur MUSABAK2, Sinasi Erol BOLU1, Mustafa KUTLU11Gulhane Military Medical Academy, Dept. of Endocrinology and Metabolism, Turkey, 2Gulhane Military Medical Academy, Dept. of Immunology, Turkey, 3Gulhane Military Medical Academy, Dept. of Clinical Biochemistry, Turkey

Obesity and Metabolism

P493

PLASMA LEVELS OF URIC ACID IN THE PATIENTS WITH FATTY LIVER.

Güngör Akçay1 , Müfide Nuran Akçay11University of Atatürk,School of Medicine,Department of Internal Medicine,Division of Endocrinology, Turkey, 2University of Atatürk,School of Medicine,Department of Surgery, Turkey

Obesity and Metabolism

P494

THE ATHEROGENIC INDEX IN THE FATTY LIVER.

Güngör Akçay1 , Müfide Nuran Akçay11University of Atatürk,School of Medicine,Department of Internal Medicine,Division of Endocrinology, Turkey, 2University of Atatürk,School of Medicine,Department of Surgery, Turkey

Obesity and Metabolism

P495

Energy and nutrients intake among overweight/obese school children in Tehran

Maryam Amini1 , Monireh Dadkhah11Nutrition Research Department, National Nutrition & Food Technology Research Institute, Iran, Islamic Republic of, 2Nutrition Research Department,National Nutrition & Food Technology Research Institute, Iran, Islamic Republic of

Obesity and Metabolism

P496

Influence of finasteride treatment on metabolic profile of men with androgenetic alopecia

Michaela Duskova1 , Martin Hill1, Luboslav Starka11Institute of Endocrinology, Czech Republic

Obesity and Metabolism

P497

Prevalence of hypo- and hypermagnesemia in an urban population

Leila siadmoradi1, Asghar Ghasemi1, Saleh Zahedi Asl1, Fereidoun Azizi21Endocrine Physiology Laboratory, Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University, Iran, Islamic Republic of, 2Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University, Iran, Islamic Republic of

Obesity and Metabolism

P498

The Effect of α-lipoic Acid on myostatin and Myosin Heavy Chain isoform profile of Skeletal Muscle of OLETF Rats

Soon Jib Yoo1 , Oak Kee Hong1, Do Man Kim2, Hyuk Sang Kwon1, Ho Young Son1, Sung Koo Kang1, Dong-Sun Kim31The Catholic University of Korea, Korea, Republic of, 2Kandong Sacred Hospital, Korea, Republic of, 3Hanyang University, Korea, Republic of

Obesity and Metabolism

P499

Comparing the activity of orlistat and sibutramine on obesity treatment

Ibrahim Sahin1, Lezzan Keskin1, Melda Comert21Division of Endocrinology and Metabolism, Department of Internal Medicine, Inonu University Medical School,, Turkey, 2Department of Internal Medicine, Inonu University Medical School,, Turkey

Obesity and Metabolism

P500

Normal metabolic flexibility despite insulin resistance in lean and obese women with polycystic ovary syndrome

Marek Straczkowski1 , Irina Kowalska1, Agnieszka Adamska1, Monika Karczewska- Kupczewska1, Agnieszka Nikolajuk1, Agnieszka Lebkowska1, Maria Gorska11Medical University of Bialystok, Department of Endocrinology, Diabetology and Internal Medicine, Poland

Obesity and Metabolism

P501

Lipid levels in anorexia nervosa patients

Marina Nikolic-Djurovic, Sandra Pekic1, Dragana Miljic1, Mirjana Doknic1, Milan Petakov1, Marko Stojanovic1, Vera Popovic11Institute of Endocrinology, Serbia

Obesity and Metabolism

P502

Prevalence of the metabolic syndrome in men with late-diagnosed Klinefelter syndrome

Daria Gusakova1 , Svetlana Kalinchenko2, George Mskhalaya2, Yuliya Tishova31Scientific and Research Institute of Urology, Russian Federation, 2Peoples’ Friendship University of Russia, Russian Federation, 3Research Center for Endocrinology, Russian Federation

Obesity and Metabolism

P503

Metabolically Healthy But Obese Individuals

Joana Mesquita1 , Selma Souto1, Ana Varela1,2, Paula Freitas1,2, Maria João Matos1,2, Miguel Ferreira3, Flora Correia1,4, Daniel Braga1,2, Davide Carvalho1,2, José Luís Medina1,21Department of Endocrinology, Hospital São João-EPE, Portugal, 2Faculty of Medicine, Universidade do Porto, Portugal, 3Department of Mathematics, Universidade do Minho, Portugal, 44Faculty of Food and Nutritional Sciences, Universidade do Porto, Portugal

Obesity and Metabolism

P504

EFFECTS OF STRESS ON KIDNEY: A HISTOCHEMICAL STUDY ON RAT MODEL

TUBA DEMIRCI1 , ELVAN ÖZBEK11ATATÜRK UNIVERSITY MEDICAL SCHOOL DEPARTMENT OF HISTOLOGY AND EMBRYOLOGY, Turkey

Obesity and Metabolism

P505

Anthropometric parameters and non alcoholic hepatic steatosis in type 2 diabetes

Leila Ben Salem Hachmi, Chiraz Bouzid1, Leila Ben farhat2, Azza Doraï1, Ridha Waghlani1, Lotfi Hendaoui2, Claude Ben Slama11National institut of nutrition, Tunisia, 2Mongi Slim Hospital, Tunisia

Endocrine Disruptors

P506

Reproductive and haematological toxicity of Nurelle D 220 EC in male rats

Mosbah Rachid1 , Boulakoud M. Salah2, Youssef I. Mokhtar31University of Boumerdes, Algeria, 2University of Annaba, Algeria, 3University of Alexandria, Egypt

Endocrine Disruptors

P507

The association between organochlorine compounds, iodine intake and thyroid hormones during pregnancy

Mar Alvarez-Pedrerol 1,2 >, Mònica Guxens1,2, Àgueda Rodriguez3, Rosa Martorell4, Mercedes Espada5, Marisa Rebagliato6, Jesús Ibarlucea5, Jordi Sunyer1,71Centre for Research in Environmental Epidemiology, Spain, 2CIBER Epidemiologia y Salud Pública (CIBERESP), Spain, 3Hospital Parc Taulí, Spain, 4Hospital de Terrassa, Spain, 5Laboratorio Normativo de Salud Pública, Spain, 6Miguel Hernandez University, Spain, 7Municipal Institute of Medical Research (IMIM-Hospital del Mar), Spain

Endocrine Disruptors

P508

HISTOPATHOLOGIC CHANGES OF EXOCRINE AND ENDOCRINE PANCREAS IN STRESS-EXPOSED FEMALE RATS

TUBA DEMIRCI1 , ELVAN ÖZBEK1, NURAY BILGE11ATATÜRK UNIVERSITY MEDICAL SCHOOL DEPARTMENT HISTOLOGY AND EMBRYOLOGY, Turkey

Endocrine Disruptors

P509

The effect of feeding of aerial part of Vaccinium myrtillus on blood glucose and lipids of diabetic rats

Mehrdad Roghani1 , Tourandokht Baluchnejadmojarad2, Samaneh Taheri31Shahed University, Iran, Islamic Republic of, 2Iran University of Medical Sciences, Iran, Islamic Republic of, 3Shahed University, Iran, Islamic Republic of

Endocrine Disruptors

P510

Effect of silymarin on nerve conduction velocity, hyperalgesia and oxidative stress in experimental diabetic neuropathy

Tourandokht Baluchnejadmojarad, Mehrdad Roghani2, Zeynab Khastehkhodaie31Iran University of Medical Sciences, Iran, Islamic Republic of, 2Shahed University, Iran, Islamic Republic of, 3Iran University of Medical Sciences, Iran, Islamic Republic of

Endocrine Disruptors

P511

Testosterone serum level in haemodialysed male patients positively correlates with adequacy of dialysis.

Małgorzata Gąsiorek1,2 , Marek Maciejewski1,2, Krzysztof Marczewski1,21Department of Nephrology, Endocrinology, Metabolic and Internal Disease with Dialyses Unit Voivodeship Hospital of Pope John Paul II, Poland, 2University of Management and Administration, Poland

Endocrine Disruptors

P512

Effects of Permethrin on sexual behaviour and plasma ‎ concentrations of pituitary-gonadal hormones in adult male ‎ NMRI mice ‎

Jalal Solati1, Mahdi Tondar1, Neda abutalebi11Islamic azad university - karaj branch, Iran, Islamic Republic of

Endocrine Disruptors

P513

Hyperprolactinaemia in men.

Elen Giorgadze 1, Shota Janjgava1, Marina Lomidze1, Tamta Bakchtadze1, Natia Nozadze1, lasha Uchava1, Nino Svani11City Clinical Hospital N4, Department of Endocrine Disorders, Georgia

Endocrine Disruptors

P514

Association of CTLA4 +49 A/G polymorphism with type 1 diabetes in Tunisian population

Benmansour jihen1 , Stayoussef Mouna1, Almawi WWassim1, Mahjoub Touhami11Universityof Monastir, Tunisia

Endocrine Disruptors

P515

Why does Klinefelter syndrome often remain undiagnosed?

Daria Gusakova1 , Svetlana Kalinchenko2, George Mskhalaya2, Yuliya Tishova31Scientific and Research Institute of Urology, Russian Federation, 2Peoples’ Friendship University of Russia, Russian Federation, 3Research Center for Endocrinology, Russian Federation

Paediatric Endocrinology

P516

Short stature in pediatric Cushing’s syndrome: effectiveness of hypercortisolism cure.

Rosa Maria Paragliola1, Rosa Maria Lovicu1, Francesca Ingraudo1, Francesca Ianni1, Pietro Locantore1, Carlo Antonio Rota1, Alfredo Pontecorvi1, Salvatore Maria Corsello11Department of Endocrinology, Catholic University School of Medicine, Italy

Paediatric Endocrinology

P517

Serum nitric oxide metabolites and clustering of metabolic syndrome components in paediatrics: an exploratory factor analysis

Asghar Ghasemi1 , Saleh Zahedi-Asl1, Fereidoun Azizi11Endocrine Physiology Laboratory, Endocrine Research Center, Research Institute for endocrine Sciences, Shahid Beheshti University (M.C.), Iran, Islamic Republic of

Paediatric Endocrinology

P518

A common deletion in the uridine diphosphate glucuronyltransferase (UGT) 2B17 gene is a strong determinant of androgen excretion in healthy pubertal boys.

Anders Juul1 , Kaspar Sørensen1, Lise Aksglæde1, Inger Garn1, Ewa Rajpert- deMetys1, Ingunn Hullstein2, Peter Hemmersbach2, Anne- Marie Ottesen11Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Denmark, 2Norwegian oping Control Laboratory, Aker University Hospital, Norway

Paediatric Endocrinology

P519

Sex Hormone-Binding Globulin Levels Predict Insulin Sensitivity, Disposition Index and Cardiovascular Risk During Puberty

Kaspar Soerensen1 , Lise Aksglaede1, Thor Munch-Andersen2, Niels Aachmann- Andersen2, Joern Helge2, Linda Hilsted3, Joergen Petersen4, Anders Juul11Dept. of Growth and Reproduction, Rigshospitalet, Denmark, 2Copenhagen muscle research center, Rigshospitalet, Denmark, 3Dept. of biochemistry, Rigshospitalet, Denmark, 4Dept. of Biostatistics, University of Copenhagen, Denmark

Paediatric Endocrinology

P520

MILD HYPOTHYROIDISM IN CHILDREN WITH CONGENITAL HEART MALFORMATIONS

Elena Passeri1, Federica Ermetici1, Massimo Carminati2, Elena Costa3, Laura Fugazzola4, Luca Persani5, Bruno Ambrosi1, Sabrina Corbetta11Endocrinology Unit, Dept Med Surg Sciences, University of Milano, IRCCS Policlinico San Donato, Italy, 2Pediatric Cardiac Surgery Unit, Dept Med Surg Sciences, IRCCS Policlinico San Donato, Italy, 3Laboratory Clinical Pathology, IRCCS Policlinico S. Donato, Italy, 4Endocrinology Unit, Fondazione Ospedale Maggiore Policlinico, Mangiagalli, Regina Elena, Italy, 5Dept Med Surg Sciences, University of Milano, Laboratory of Sperimental Endocrinology, IRCCS Istituto Auxologico Italiano, Italy

Paediatric Endocrinology

P521

Increased intra-erythrocyte magnesium is associated with gamma-glutamyl transferase in obese children

Maryam Tohidi1 , Asghar Ghasemi2, Farzad Hadaegh1, Shamsi Arbabi1, Firoozeh Hosseini Isfahani3, Fereidoun Azizi211- Prevention of Metabolic Disorders Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University (M.C.), Iran, Islamic Republic of, 22- Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University (M.C.), Iran, Islamic Republic of, 33- Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University (M.C.), Iran, Islamic Republic of

Paediatric Endocrinology

P522

IODINE LEVELS AND THYROID HORMONES IN HEALTHY PREGNANT WOMEN AND BIRTH WEIGHT OF THEIR OFFSPRING

Mar Alvarez-Pedrerol, Mònica Guxens1,2, Michelle Mendez1, Yolanda Canet3, Rosa Martorell4, Mercedes Espada5, Estel Plana1,2, Marisa Rebagliato2,6, Jordi Sunyer1,71Centre for Research in Environmental Epidemiology, Spain, 2CIBER Epidemiologia y Salud Pública (CIBERESP), Spain, 3Hospital Parc Taulí, Spain, 4Hospital de Terrassa, Spain, 5Laboratorio Normativo de Salud Pública, Departamento de Sanidad Gobierno Vasco, Spain, 6Miguel Hernandez University, Spain, 7Municipal Institute of Medical Research (IMIM-Hospital del Mar), Spain

Paediatric Endocrinology

P523

Development of multiple pituitary hormone deficiency (MPHD) in pediatric patients originally diagnosed with isolated GH deficiency (IsGHD)

Werner Blum1 , Cheri Deal2, Alan Zimmermann3, Elena Shavrikova4, Catherine Sampson5, Anja Ignatenko4, Christopher Child6, Ron Rosenfeld71Eli Lilly and Company, Germany, 2University of Montreal, Canada, 3Eli lilly and Company, United States, 4Pharma Support Inc., Russian Federation, 5i3 Statprobe, United States, 6Eli Lilly and Company, United Kingdom, 7Lucile Packard Foundation and ProteoGenix Inc., United States

Paediatric Endocrinology

P524

Clinical and Genetic Features of Type 1 Diabetes Mellitus and Autoimmune Thyroiditis Combination in Belarusian Children

Liudmila Viazova1 , Angelika Solntseva1, Elena Aksenova1, Tatiana Pokladok1, Nina Danilenko1, Michail Maitak112 city children's hospitals, Belarus, 2Belarus state medical university, Belarus, 3Belarus National Academy of Sciences, Genetic and cytology institution, Belarus, 4Belarus National Academy of Sciences, Genetic and cytology institution, Belarus, 5Belarus National Academy of Sciences, Genetic and cytology institution, Belarus, 6Belarus state medical university, Belarus

Paediatric Endocrinology

P525

LEOPARD syndrome and pilocytic astrocytoma – a random association?

Carmen Vulpoi1 , Cristina Rusu1, Martin Zenker2, Ion Poeata1, Aurora Constantinescu1, Anca Indrei1, Ioana Stoica1, Eusebie Zbranca11University of Medicine, Romania, 2Humangenetisches Institut, Germany

Paediatric Endocrinology

P526

Genetic characterization of children with isolated Growth Hormone Deficiency in Turkish Population

Ahmet Arman1 , Ajda Coker2, Ergun Cetinkaya3, Bumin Dundar4, Zeynep Siklar5, Ozlem Sarioz6, Atilla Buyukgebiz71The Faculty of Engineering, Marmara University, Turkey, 2The Department of Molecular Biology and Genetics, Kultur University, Turkey, 3The Department of Pediatric Endocrinology, SB Ankara Diskapi Children Hospital, Turkey, 4The Department of Pediatric Endocrinology, Suleyman Demirel University, Turkey, 5The Department of Pediatric Endocrinology, Ankara University, Turkey, 6The Department of Biology, Marmara University, Turkey, 7The Department of Pediatric Endocrinology, Acibadem Hospital, Turkey

Paediatric Endocrinology

P527

Growth hormone receptor (GHR) mutations in Turkish Children with Laron Syndrome

Ajda COKER1 , Ahmet ARMAN2, Ozlem SARIOZ3, Bilgin YUKSEL4, Alev OZON51The Department of Molecular Biology and Genetics, Istanbul Kultur University, Turkey, 2The Faculty of Engineering, Marmara University, Turkey, 3The Department of Biology, Marmara University, Turkey, 4The Department of Pediatrics, Division of Endocrinology, Cukurova University, Turkey, 5The Department of Pediatrics, Division of Endocrinology, Hacettepe University, Turkey

Paediatric Endocrinology

P528

CHILDHOOD OBESITY AND BONE AGE

Vassilios Petrou1 , Athanasia Tertipi1, Thomas Georgoulas1, Eleni Papastathi1, Maria Deligeorgi1, Vassiliki Skarpa1, Asteroula Papathanasiou11Children's Hospital of Athens " P. and A. Kyriakou ", Greece

Paediatric Endocrinology

P529

THE EFFECT OF ONE YEAR OF THERAPY WITH RHGH ON GROWTH VELOCITY IN PATIENTS WITH GROWTH HORMONE DEFICIENCY (GHD).

Teresa Zak1 , Agnieszka Zubkiewicz1, Anna Noczynska11Department of Endocrinology and Diabetology for Children and Adolescents UM, Poland

Paediatric Endocrinology

P530

THE GOITER ETIOLOGY IN CHILDREN OF THE SOUTH WEST OF ROMANIA

Marginean Otilia1 , Simedrea Ioan1, Lesovici Marilena1, Crista Corina21. Ist Pediatric Clinic, “Louis Turcanu” Children Hospital,, Romania, 2Endocrinology Department, Country Hospital,, Romania

Paediatric Endocrinology

P531

Influence of the Exon 3 – deleted polymorphism of the GH receptor on glucose and lipid metabolism in GH treated subjects with GH deficiency: results of a preliminary study

Michela Baiocchi1, Chiara Donati1, Mara Maselli3, Patrizia Mella2, Elena Prandi1, Alba Pilotta1, Giorgio Radetti3, Fabio Buzi11Auxoendocrinologia, Clinica Pediatrica, University of Brescia, Italy, 2Istituto di Medicina Molecolare A. Nocivelli, University of Brescia, Italy, 3Department of Paediatrics, Regional Hospital, Italy

Paediatric Endocrinology

P532

“Hidden” Congenital Adrenal Hyperplasia – Case Report

Monica Livia Gheorghiu 1,2 >, Corina Chirita1, Olga Ianas1, Andra Caragheorgheopol1, Anda Dumitrascu11“C.I. Parhon” Institute of Endocrinology, Romania, 2“Carol Davila” University of Medicine and Pharmacy, Romania

Paediatric Endocrinology

P533

Prevalence of autoimmune thyroiditis in children with diabetes mellitus

Andreia Veloza1 , Catarina Coelho1, Isabel Manita1, Maria Cordeiro1, Dolores Passos1, Luísa Raimundo1, Jorge Portugal11Hospital Garcia de Orta, Portugal

Growth and Developmental Endocrinology

P534

Characterization of growth hormone (GH) mutants R77C and D112G found in patients with retarded growth

Riia Junnila1 , Friederike Braig1, Katri Piilonen1, Christian Strasburger1, Zida Wu11Div. of Clinical Endocrinology, Charité Campus Mitte, Charité Universitätsmedizin, Germany

Growth and Developmental Endocrinology

P535

The effect of fetal hypothyroidism on carbohydrate metabolism during adulthood in rats

Hamid Farahani1, Saleh Zahedi Asl1, Asghar Ghasemi11Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Iran, Islamic Republic of

Growth and Developmental Endocrinology

P536

Development of specific monoclonal antibodies and highly sensitive immunoassays for 20 kDa and 22 kDa human growth hormone (hGH)

Zida Wu 1 , Emral Devany1, Giovanna Lima2, Martin Bidlingmaier3, Charistian Strasburger11Department of Internal Medicine, Campus Charite Mitte, Universitaetsmedizin Berlin, Germany, 2Department of Internal Medicine, Universidade Federal do Rio de Janeiro, Brazil, 3Medical Clinic, University Hospital Innenstadt, Ludwig Maximilians University, Germany

Growth and Developmental Endocrinology

P537

The Effect of Gestational Hypothyroidism on Insulin Secretion from Isolated Islets of Adult Offspring in Male Rats

Saleh Zahedi-Asl1 , Hamid Farahani2, Asghar Ghasemi1, Farzaneh Faraji1, Homa Manaheji21Endocrine Physiology Laboratory, Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University (M.C.), Iran, Islamic Republic of, 2Department of Physiology, The Medical School, Shahid Beheshti University (M.C.), Iran, Islamic Republic of

Growth and Developmental Endocrinology

P538

Short stature in betathalassemia major-a multifactorial condition

Alice Albu1 , Anca Zirnea1, Florentina Vladareanu2, Daniela Voicu2, Larisa Nitu2, Suzana Florea1, Simona Fica1,31Elias Hospital, Romania, 2National Institute of Transfusional Haematology, Romania, 3University of Medicine and Pharmacy Carol Davila, Romania

Growth and Developmental Endocrinology

P539

HISTOPATHOLOGIC CHANGES IN PREGNANT RAT PANCREAS

ELVAN ÖZBEK1, TUBA DEMIRCI11ATATÜRK UNIVERSITY MEDICAL SCHOOL DEPARTMENT OF HISTOLOGY AND EMBRYOLOGY, Turkey

Growth Factors

P540

IGFBP3 and IGFBP2 negatively and positively modulate IGFs autocrine effect in lung cancer cell lines

Marica Arvigo1 , Federico Gatto1, Pietro Ameri1, Diego Ferone1, Francesco Minuto11Dept of Endocrinology and Medical Sciences and Centre of Excellence for Biomedical Research, University of Genova, Italy

Growth Factors

P541

Exogenous growth hormone administration effects organ weights but does not markedly change serum IGF-I levels in common mice

Moritz Kummann1 , Max Bielohuby1, Jenny Manolopoulou1, Martin Bidlingmaier11Medizinische Klinik - Innenstadt, LMU, Germany

Growth Factors

P542

Immunohistochemical analysis of VEGF and CD34 in adrenal cortical tumors

Timur Britvin1 , Larisa Gurevich1, Irina Kazantseva1, Arian Kalinin11Moscow Regional M.F. Vladimirsky Clinical Research Institute, Russian Federation

Growth Factors

P543

Effects of intraperitoneal Gibberelic acid (GA3) on IGF-1 and Growth Hormone (GH) in the rats

Berna Afacan1 , Nuray Erin1, Özkan Ulusoy1, Mustafa Kemal BALCI11AKDENIZ UNIVERSITY, Turkey

Neuroendocrinology, Pituitary and Behaviour

P544

The effects of selective serotononin reuptake inhibitors on the thyroid axis in perimenopausal depression

Sokratis Karaoulanis1 , Andreas Rizoulis2, Georgios Lalios3, Eleni Damani4, Katerina Rizouli4, Nikos Liakos4, Alexandros Papadimitriou5, Nikiforos Angelopoulos11Department of Psychiatry, University of Thessaly, Greece, 2Department of Medicine, psychiatric Hospital of Attici, Greece, 3Department of Obstetrics and Gynecology, University Hospital of Larissa, Greece, 4Biochemical Laboratory, University Hospital of Larissa, Greece, 5Department of Neurology, university Hospital of Larissa, Greece

Neuroendocrinology, Pituitary and Behaviour

P545

Pre-treatment IGF-I concentrations predict radiographic osteoarthritis in acromegalic patients with long-term cured disease

Nienke R Biermasz1 , Moniek JE Wassenaar1, Agatha A van der Klaauw1, Alberto M Pereira1, Johannes WA Smit1, Ferdinand Roelfsema1, Ron Wolterbeek1, Herman M Kroon1, Margreet Kloppenburg1, Johannes A Romijn11leiden university medical center, Netherlands

Neuroendocrinology, Pituitary and Behaviour

P546

The Prevalence of Diabetes Mellitus in 9776 Adult Patients with Childhood- and Adult-Onset Growth Hormone (GH) Deficiency before GH Replacement. A KIMS Analysis

Roger Abs1 , Anton Luger2, Patrick Wilton3, Maria Thunander4,5, Johan Verhelst6, Miklos Goth7, Maria Koltowska-Haggstrom8, Anders Mattsson81Department of Endocrinology, University of Antwerp, Belgium, 2Universitätsklinik fur Innere Medizin III, Klinik Abt. fur Endokrinologie und Stoffwechsel, Austria, 3Pfizer Endocrine Care, Pfizer Ltd., United States, 4Department of Internal Medicine, Central Hospital, Sweden, 5Department of Diabetology and Endocrinology, Lund University, Sweden, 6Department of Endocrinology, General Hospital Middelheim,, Belgium, 7Division of Endocrinology, Department of Medicine, National Medical Centre, Hungary, 8KIMS Medical Outcomes, Pfizer Endocrine Care, Sweden

Neuroendocrinology, Pituitary and Behaviour

P547

Effects of 3 years growth hormone (GH) replacement in adult-onset growth hormone deficiency (GHD) due to controlled Cushing’s disease (CD)

Charlotte Hoybye1 , Peter J Jonsson2, Ulla Feldt-Rasmussen3, Oskar Ragnarsson4, Peter Trainer5, Beverly Biller6, Maria Koltowska- Haggstrom21Department of Endocrinology, Metabolism and Diabetology, Karolinska University Hospital, Sweden, 2KIMS Medical Outcomes, Pfizer Endocrine Care, Sweden, 3Department of Medical Endocrinology, Rigshospitalet, Denmark, 4Sahlgrenska University Hospital, Sweden, 5Department of Endocrinology, Christie Hospital, United Kingdom, 6Neuroendocrine Unit, Massachusetts General Hospital, Harvard Medical School, United States

Neuroendocrinology, Pituitary and Behaviour

P548

The cost-effectiveness of growth hormone (GH) treatment (Genotropin®) in adult patients with growth hormone deficiency (GHD)

Kristian Bolin1 , Bjorn Jonsson2, Maria Koltowska-Haggstrom3, Christin Prutz4, Rickard Sandin41Department of Economics and Lund University Centre for Health Economics, Sweden, 2Department of Women´s and Children´s Health, Uppsala University, Sweden, 3KIMS Medical Outcomes, Pfizer, Endocrine Care, Sweden, 4Pfizer Sweden AB, Sweden

Neuroendocrinology, Pituitary and Behaviour

P549

High TSH levels in healthy pregnant women are related to a decrease in motor development of their children at 14 months of age.

Mar Alvarez1,2 , Jordi Júlvez1, Mònica Guxens1,2, Àgueda Rodriguez3, Rosa Martorell4, Mercedes Espada5, Jordi Sunyer1,61Centre for Research in Environmental Epidemiology, Spain, 2CIBER Epidemiologia y Salud Pública (CIBERESP), Spain, 3Hospital Parc Taulí, Spain, 4Hospital de Terrassa, Spain, 5Laboratorio Normativo de Salud Pública, Spain, 6Municipal Institute of Medical Research (IMIM-Hospital del Mar), Spain

Neuroendocrinology, Pituitary and Behaviour

P550

Growth Hormone Receptor polymorphism and the effects of Pegvisomant in acromegaly

Antonio Bianchi1 , Gherardo Mazziotti2, Laura Tilaro1, Vincenzo Cimino1, Teresa Porcelli1, Marilda Mormando1, Linda Tartaglione1, Alfredo Pontecorvi1, Andrea Giustina2, Laura De Marinis11Department of Endocrinology, Catholic University, School of Medicine, Italy, 2Department of Medical and Surgical Sciences, University of Brescia, Italy

Neuroendocrinology, Pituitary and Behaviour

P551

The low-dose ACTH stimulation test in the assessment of outcome of pituitary surgery for Cushing’s disease

Rehmat A. Alwani1 , Wouter W. De Herder1, Frank H. De Jong1, Aart-Jan Van der Lely1, Richard A. Feelders11Erasmus Medical Centre, Netherlands

Neuroendocrinology, Pituitary and Behaviour

P552

The D3 GH receptor polymorphism is associated with osteoarthritis, especially of the hip, in patients with long-term cured acromegaly

Moniek JE Wassenaar1 , Nienke R Biermasz1, Agatha A van der Klaauw1, Johannes WA Smit1, Alberto M Pereira1, Ferdinand Roelfsema1, Tahar van der Straaten1, Herman M Kroon1, Margreet Kloppenburg1, HJ Guchelaar1, Johannes A Romijn11leiden university medical center, Netherlands

Neuroendocrinology, Pituitary and Behaviour

P553

GHRELIN AS NEW PROVOCATIVE TEST FOR THE DIAGNOSIS OF GH DEFICIENCY IN ADULTS

Valentina Gasco1 , Silvia Rovere1, Guglielmo Beccuti1, Fabio Broglio1, Gianluca Aimaretti2, Silvia Grottoli1, Felipe Casanueva3, Ezio Ghigo11Department of Internal Medicine, Division of Endocrinology and Metabolism, University of Turin, Italy, 2Endocrinology, Department of Clinical and Experimental Medicine, University of Eastern Piedmont, Italy, 3Endocrine Division, Department of Medicine, Santiago de Compostela University, Spain

Neuroendocrinology, Pituitary and Behaviour

P554

SCREENING FOR NEUROENDOCRINE DYSFUNCTION IN PATIENTS AFTER SPONTANEOUS SUBARACHNOID HEMORRHAGE

Sandra Pekic Djurdjevic, Vladimir Jovanovic2, Marko Stojanovic1, Branko Djurovic2, Mirjana Doknic1, Dragana Miljic1, Marina Nikolic-Djurovic1, Vera Popovic11Institute of Endocrinology, University Clinical Center, Serbia, 2Institute of Neurosurgery,University Clinical Center, Serbia

Neuroendocrinology, Pituitary and Behaviour

P555

Characterisation of PARS, a novel putative pituitary regulator of hormone secretion

Marie Helene Reiter1 , Greisa Vila1, Engelbert Knosp2, Ludwig Wagner1, Anton Luger11Division of Endocrinology and Metabolism, Department of Medicine III, Medical University of Vienna, Austria, 2Department of Neurosurgery, Medical University of Vienna, Austria

Neuroendocrinology, Pituitary and Behaviour

P556

Combined treatment for acromegaly with long-acting somatostatin analogues and pegvisomant: Long-term safety up to 4.5 years of follow-up in 86 patients

sebastian neggers1 , wouter de herder1, Joop Janssen1, Richard feelders1, Aart-Jan van der Lely11erasmus university medical center, Netherlands

Neuroendocrinology, Pituitary and Behaviour

P557

Impact of long-term growth hormone (GH) substitution on lipid metabolism and bone mineralisation (BMD) in pituitary insufficient patients with growth hormone deficiency (GHD)

Josefine Roemmler1 , Maren Kuenkler1, Jochen Schopohl11Department of Internal Medicine (Endocrinology) – Innenstadt, University of Munich, Germany

Neuroendocrinology, Pituitary and Behaviour

P558

Effect of intracerebroventricular infusion of bombesin in glucose dependent insulinotropic peptide on conscious dogs

Maria Yavropoulou1 , Olympia Anastasiou1, Kalliopi Kotsa1, John Yovos11Aristotle University of Thessaloniki, Greece

Neuroendocrinology, Pituitary and Behaviour

P559

Plurihormonal cells are more frequent in early embryofetal stages of the human pituitary

Andy R.M. Chirculescu1, John F Morris2, Mihail Gr Coculescu31Department of Anatomy, University of medicine and Pharmacy "Carol Davila", Romania, 2Department of Physiology, Human Anatomy and Genetics, Oxford University, United Kingdom, 3Department of Endocrinology, University of Medicine and Pharmacy "Carol Davila", Romania

Neuroendocrinology, Pituitary and Behaviour

P560

Ovariectomy causes hippocampal neuronal loss and cognitive dysfunction and restored by Ginkgo biloba extract EGb761 in rats

Koji Koike1 , Kazuhiro Takuma2, Yuki Hoshina1, Nobutaka Suzuki1, Masaki Inoue1, Kiyofumi Yamada31Kanazawa University, Japan, 2Osaka University, Japan, 3Nagoya University, Japan

Neuroendocrinology, Pituitary and Behaviour

P561

Glucose tolerance and somatostatin analogues treatment in acromegaly. A 12 month open, prospective study.

Annamaria Colao1 , Renata S Auriemma1, Silvia Savastano1, Mariano Galdiero1, Ludovica FS Grasso1, Gaetano Lombardi1, Rosario Pivonello11Department of Molecular and Clinical Endocrinology and Oncology, University Federico II of Naples, Italy

Neuroendocrinology, Pituitary and Behaviour

P562

HEART RATE VARIABILITY OF YOUNG MEN WITH HYPOGONADOTROPIC HYPOGONADISM

FERHAT DENIZ1 , NECIP ERMIS1, ALPER KEPEZ1, BATUHAN KARA1, AZAL OMER21ETIMESGUT MILITARY HOSPITAL, Turkey, 2GULHANE MILITARY MEDICAL ACADEMY, Turkey

Neuroendocrinology, Pituitary and Behaviour

P563

The impact of infertility on the relationship of people with a Pituitary condition

Marianne Morris1 , Pascale Harrison11University of the West of England, United Kingdom

Neuroendocrinology, Pituitary and Behaviour

P564

CAROTID INTIMA MEDIA THICKNESS AND OTHER CARDIOVASCULAR RISK FACTORS IN ACROMEGALIC PATIENTS

Seda Sancak1 , Ayse Serap Yalin1, Beste Ozben2, Oguzhan Deyneli1, Mutlu Gunes1, Dilek Gogas Yavuz1, Nefise Sema Akalin11Marmara University, School of Medicine, Section of Endocrinology and Metabolism, Turkey, 23Marmara University, School of Medicine, Department of Cardiology, Turkey

Neuroendocrinology, Pituitary and Behaviour

P565

Expression and regulation of HIF-1a and RSUME in murine and human pituitary tumor cells

Bing Shan1 , Marily Theodoropoulou1, Michael Buchfelder2, Walter Rachinger3, Marco Losa4, Günter Stalla1, Eduardo Arzt5, Ulrich Renner11Max Planck Institute of Psychiatry, Germany, 2University of Erlangen-Nuremburg, Germany, 3University of Munich, Germany, 4Istituto San Raffaele, Italy, 5FCEN-Universidad de Buenos Aires, Argentina

Neuroendocrinology, Pituitary and Behaviour

P566

MicroRNA expression in human sporadic pituitary adenomas

Henriett Butz1 , István Likó2, Belema Boyle1, Sándor Czirják3, Péter Igaz1, Attila Patócs4, Károly Rácz112nd Department of Medicine, Semmelweis University, Faculty of Medicine, Hungary, 2Gedeon Richter Ltd., Hungary, 3National Institute of Neurosurgery, Hungary, 4Molecular Medicine Research Group, the Hungarian Academy of Sciences and the Semmelweis University, Hungary

Neuroendocrinology, Pituitary and Behaviour

P567

PROGESTERONE UP-REGULATES TRANSTHYRETIN LEVELS IN PRIMARY CULTURES OF CHOROID PLEXUS EPITHELIAL CELLS

Telma Quintela1 , Henrique Alves1, Isabel Gonçalves1, Graça Baltazar1, Cecília Santos11Centre of Investigation in Health Sciences – CICS, University of Beira Interior, Portugal

Neuroendocrinology, Pituitary and Behaviour

P568

Long-term follow-up of female patients with prolactinoma : Is there a place for surgery in the therapy of prolactinoma?

Janine Frey1 , Ina Krull1, Rahel Sahli1, Christoph Stettler1, Stefan Fischli1, Peter Diem1, Emanuel Christ11Division of Endocrinology, Diabetology and CLinical Nutrition, University hospital of Bern, Inselspital, Switzerland

Neuroendocrinology, Pituitary and Behaviour

P569

Clinical presentation, long-term follow-up and bone morbidity of male patients with prolactinoma

Janine Frey1 , Ina Krull1, Rahel Sahli1, Christoph Stettler1, Stefan Fischli1, Peter Diem1, Emanuel Christ11Division of Endocrinology, Diabetology and Clinical Nutrition, University Hospital of Bern, Inselspital, Switzerland

Neuroendocrinology, Pituitary and Behaviour

P570

Effects of somatostatin analogs on glucose homeostasis: a meta-analysis of acromegaly studies.

Gherardo Mazziotti1 , Irene Floriani2, Stefania Bonadonna1, Valter Torri2, Philippe Chanson3, Andrea Giustina11University of Brescia, Italy, 2Istituto di Ricerche Farmacologiche “Mario Negri”, Italy, 3Université Paris-Sud, France

Neuroendocrinology, Pituitary and Behaviour

P571

Macroprolactinemia in patients with pituitary adenomas.

L. K. Dzeranova1, E. N. Giniyatullina1, I. I. Barmina2,1, A. D. Dobracheva1, N. P. Goncharov11Russian Research Centre for Endocrinology, Russian Federation, 2Moscow Medical Academy of I. M. Sechenov, Saint Helena

Neuroendocrinology, Pituitary and Behaviour

P572

Primary medical treatment of large and giant prolactinomas.

Ludmila Astafieva1 , Boris Kadashev11N.N. Burdenko Neurosurgery Institute, Russian Federation

Neuroendocrinology, Pituitary and Behaviour

P573

Transport activities and plasma membrane localization of MCT8 mutant proteins identified in patients with severe psychomotor retardation depend on cell type. Implications for the interpretation of clinical phenotypes

Anita Kinne1 , Stephan Roth1, Ulrich Schweizer1, Joseph Köhrle11Charite-Berlin, Institute for Experimental Endocrinology, Germany

Neuroendocrinology, Pituitary and Behaviour

P574

Is it possible to avoid hypopituitarism after the irradiation of pituitary adenomas by the Leksell gamma-knife?

Josef Marek1 , Jana Jezkova1, Vaclav Hana1, Michal Krsek1, Roman Liscak2, Vilibald Vladyka211 Faculty of Medicine, Charles University, Czech Republic, 2Hospital na Homolce, Czech Republic

Neuroendocrinology, Pituitary and Behaviour

P575

Effect of prolonged treatment with potassium canrenoate, a MR antagonist, on basal and stimulated hypothalamus-pituitary-adrenal (HPA) axis in humans

Rita Berardelli1 , Elisa Marinazzo1, Elisa Prats1, Andreea Picu1, Roberta Giordano2, Ezio Ghigo1, Emanuela Arvat11University of Turin, Department of Internal Medicine, Division of Endocrinology and Metabolism, Italy, 2University of Turin, Department of Clinical and Biological Science,, Italy

Neuroendocrinology, Pituitary and Behaviour

P576

Initial and long-term outcome of surgery in acromegaly: a ten-year, single centre study in 115 patients.

Frédérique Albarel1 , Frédéric Castinetti1, Isabelle Morange1, Noémie Dubois1, Henry Dufour2, Bernard Conte-Devolx1, Thierry Brue11Department of Endocrinology, France, 2Department of Neurosurgery, France

Neuroendocrinology, Pituitary and Behaviour

>P577

Two repeated restraint stress paradigms differing in duration and frequency result in similar levels of HPA habituation, but differences in neuropeptide expression and testosterone levels.

Megan Gray1 , Brenda Bingham1, Victor Viau11Univ. of British Columbia, Canada

Neuroendocrinology, Pituitary and Behaviour

P578

Association of Interleukin-6 with hot flashes in perimenopausal women

Sokratis Karaoulanis1 , Katerina Rizouli2, Andreas Rizoulis3, Georgios Lalios4, Katerina Theodoridou2, Nikiforos.V Angelopoulos11Department of Psychiatry, University of Thessaly, Greece, 2Department of Immunology, University of Thessaly, Greece, 3Department of Medicine, Psychiatric Hospital of Attiki, Greece, 4Department of Obstetrics and Gynecology, University Hospital of Larissa, Greece

Neuroendocrinology, Pituitary and Behaviour

P579

Empty Sella And Primary Autoimmune Hypothyroidism

Rogelio Garcia-Centeno1 , Jose-Pablo Suarez-Llanos2, Elisa Fernandez-Fernandez1, Victor Andia- Melero1, Marcel Sambo1, Petra Sanchez1, Antonino Jara -Albarran11Hospital General Universitario Gregorio Marañon, Spain, 2Hospital Nuestra Señora de la Candelaria, Spain

Neuroendocrinology, Pituitary and Behaviour

P580

Human corticotropin releasing hormone (hCRH) test performance in the differential diagnosis between Cushing’s disease and pseudo-Cushing state is enhanced by combined ACTH and cortisol analysis

Giacomo Tirabassi1 , Giorgio Arnaldi1, Roberta Papa1, Giorgio Furlani1, Laura Trementino1, Marina Cardinaletti1, Emanuela Faloia1, Marco Boscaro11Clinica di Endocrinologia, Italy

Neuroendocrinology, Pituitary and Behaviour

P581

Hemostatic and fibrinolytic changes in patients with Cushing’s disease.

Juliya Chodakova1 , Svetlana Arapova1, Lidiya Chirkova1, Ludmila Rozhinskaya1, Galina Suhanova21National Endocrinology Research Center, Russian Federation, 2National Hematology Research Center, Russian Federation

Neuroendocrinology, Pituitary and Behaviour

P582

IMMUNOASSAY DETERMINATION OF MACROPROLACTIN IN HYPERPROLACTINEMIC PATIENTS: AN INTERASSAY COMPARATIVE STUDY

Mariana Martinho1 , Teresa Martinho1, Nuno Cunha1, Fatima Curado1, Leonor Gomes2, Frederico Valido1, Plamen Naidenov1, Fernando Rodrigues11Portuguese Institute of Oncology of Coimbra, Portugal, 2Coimbra’s University Hospital, Portugal

Neuroendocrinology, Pituitary and Behaviour

P583

Adiponectin and visfatin: a link with bone mineral density in acromegaly

Eugenia Resmini1 , Nuria Sucunza2, M.Jose Barahona1, Alicia Santos1,2, J.Maria Fernández-Real3, Wilfredo Ricart3, J.Maria Moreno3, José Farrerons4, José Rodríguez Espinosa5, AM Marin4, Susan M Webb11Hospital Sant Pau, CIBER-ER Unidad 747, Endocrinology, Spain, 2Hospital Manacor, Spain, 3Hospital Josep Trueta, Spain, 4Internal Medicine, Hospital Sant Pau, Spain, 5Biochemistry Department, Hospital Sant Pau, Spain

Neuroendocrinology, Pituitary and Behaviour

P584

Feedback inhibition of prednisolone on vasopressin (AVP) secretion but preserved renal water reabsorption after thirsting point to an AVP independent antidiuretic action

Friederike Ufer1, Knut Mai1, Sven Diederich2, Erling Pedersen3, Andreas Pfeiffer1, Volker Bähr11Charité, CBF, Endocrinology, Diabetes and Human Nutrition, Germany, 2Endokrinologikum, Germany, 3Holstebro Hospital, Aarhus University, Department of Medical Research, Denmark

Neuroendocrinology, Pituitary and Behaviour

P585

Genetic alterations of phosphodiesterase 11A (PDE11A) in acromegalic patients

Erika Peverelli1 , Federica Ermetici1, Marcello Filopanti1, Andrea Lania1, Stefano Ferrero2, Paolo Beck-Peccoz1, Anna Spada11Dpt of Medical Sciences, University of Milan, Endocrinology and Diabetology Unit, Fondazione Ospedale Maggiore IRCCS, Italy, 2Dpt of Medicine, Surgery and Dentistry, Pathology Unit, Azienda Ospedaliera San Paolo e Ospedale Maggiore, Italy

Neuroendocrinology, Pituitary and Behaviour

P586

NEUROENDOCRINE EFFECTS OF STRESS IN HOSTILE HEAVY SOCIAL DRINKERS: EXPLORING THE INVOLVEMENT OF SEROTONIN USING DIETARY TRYPTOPHAN MANIPULATION

Jelena Nesic1 , Theodora Duka11University of Sussex, United Kingdom

Neuroendocrinology, Pituitary and Behaviour

P587

GH response to oral glucose tolerance test: a comparison between patients with pituitary disease and healthy subjects.

Elisa Verrua1 , Cristina Lucia Ronchi1, Daniela Ilaria Ferrari1, Luca Olgiati1, Emanuele Ferrante1, Marcello Filopanti1, Andrea Gerardo Lania1, Paolo Beck-Peccoz1, Anna Spada11Department of Medical Science, University of Milan, Unit of Endocrinology and Diabetology, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Italy

Neuroendocrinology, Pituitary and Behaviour

P588

Quality of life (QoL) in patients with Cushing´s syndrome in a Spanish population: new experience with the CushingQoL questionnaire.

Santos Alicia1,2 , Resmini Eugenia1,2, Barahona MªJosé2, Martí Camelia1,2, Farkas Cheryl1, Roig Olga1,2, Martínez Mª Antonia1,2, Sucunza Nuria2, Badia Xavier3,2, Webb Susan M1,21Hospital Sant Pau, Spain, 2CIBER-ER Unidad 747, Spain, 3Health Economics and Outcomes Research, IMS Health, Spain

Neuroendocrinology, Pituitary and Behaviour

P589

FIVE YEAR EXPERIENCE WITH GH REPLACEMENT THERAPHY ON TUMOR OCCURRENCE OR RECURRENCE: ONE CENTER STUDY.

Carolina Di Somma1 , Francesca Rota1, Maria Cristina Savanelli1, Gaetano Lombardi1, Annamaria Colao11Federico II University, Italy

Neuroendocrinology, Pituitary and Behaviour

P590

Androgen Deficiency is Additional Risk Factor for Bone Health In Growth Hormone Deficient Men

Marko Stojanovic1 , Sandra Pekic1, Dragana Miljic1, Marina Nikolic-Djurovic1, Mirjana Doknic1, Vera Popovic11Neuroendrocrine Unit, Institute of Endocrinology, University Clinical Center of Serbia, Serbia

Neuroendocrinology, Pituitary and Behaviour

P591

The correlations of ghrelin concentrations and lipid profile in patients with acromegaly.

Magdalena Jaskula1 , Ryszard Wasko1, Hanna Komarowska1, Aleksandra Dziubandowska1, Jerzy Sowinski11University Of Medical Sciences, Department of Endocrinology, Metabolism and Internal Diseases, Poland

Neuroendocrinology, Pituitary and Behaviour

P592

Glucose metabolism alterations in acromegaly

Maria Rosaria Ambrosio, Alessandra Malaspina1, Grazia De Paola1, Marta Bondanelli1, Maria Chiara Zatelli1, Ettore degli Uberti11Dept of Biomedical Sciences and Advanced Therapies, Section of Endocrinology, University of Ferrara, Italy

Neuroendocrinology, Pituitary and Behaviour

P593

ACTH-secreting bronchial carcinoid: a role of somatostatin analogues in diagnosis and treatment

Maria Pavlova1 , Dmitry Koloda1, Vyacheslav Pronin1, Polina Zykova1, Sergey Harnas1, Leonid Ippolitov1, Alexey Egorov1, Georgy Polunin1, Pavel Yankin11Moscow Medical Academy, Russian Federation

Neuroendocrinology, Pituitary and Behaviour

P594

Dose interval comparison of Lanreotide Autogel 120mg in acromegalic patients previously treated with Octreotide LAR

Jochen Schopohl1 , Klaus Badenhoop2, Felix Beuschlein1, Michael Droste3, Ursula Plöckinger4, Stephan Petersenn5, Christian Strasburger61Medizinische Klinik Innenstadt, Germany, 2Endokrinlogie, Germany, 3Endokrinologie Praxis, Germany, 4Campus Virchow, Germany, 5Endokrinologie, Germany, 6Campus Mitte, Germany

Neuroendocrinology, Pituitary and Behaviour

P595

Growth Hormone Replacement Therapy in Adult Onset Growth Hormone Deficiency induces favorable long-term effects on Quality of Life, Bone, Body Composition and Lipids: A 55 month prospective study

Anders Palmstrøm Jørgensen 1,3 >, Krisitan J Fougner2, Thomas Schreiner1, Jens Bollerslev11Rikshospitalet University Hospital, Norway, 2St.Olavs University Hospital, Norway, 3Aker University Hospital, Norway

Neuroendocrinology, Pituitary and Behaviour

P596

GH deficiency in HIV-infected patients with lipodystrophy: preliminary data on the effects of r-hGH treatment on body composition.

Lucia Zirilli1, Gabriella Orlando2, Giulia Brigante1, Nicola Squillace2, Chiara Diazzi1, Cesare Carani1, Giovanni Guaraldi2, Vincenzo Rochira11Endocrinology and Metabolism, University of Modena and Reggio Emilia, Italy, 2Unit of Infectious Disease, University of di Modena and Reggio Emilia, Italy

Neuroendocrinology, Pituitary and Behaviour

P597

Can the pineal gland modulate the effects of kisspeptin on the puberty onset in female rats?

Haluk Kelestimur1 , Bayram Yilmaz2, Ahmet Ayar1, Ertugrul Kilic2, Mete Ozcan1, Ulkan Kilic2, Ergul Alcin11Firat University, Faculty of Medicine, Turkey, 2Yeditepe University, Faculty of Medicine, Turkey

Neuroendocrinology, Pituitary and Behaviour

P598

Central diabetes insipidus after transsphenoidal treatment for tumors of the sellar region: prognostic factors for transient course of the disease.

Ekaterina Pigarova1 , Liudmila Rozhinskaya1, Andrey Grigoriev1, Larisa Dzeranova11Research Centre for Endocrinology, Russian Federation

Neuroendocrinology, Pituitary and Behaviour

P599

FOOD DEPRIVATION AFFECTS ARCUATE NEURONS IN THE HYPOTHALAMUS OF YOUNG RATS

Jolanta Kubasik-Juraniec, Narcyz Knap11Medical University of Gdansk, Department of Electron Microscopy, Poland, 2Medical University of Gdansk, Department of Medical Chemistry, Poland

Neuroendocrinology, Pituitary and Behaviour

P600

Plasma levels of Neuropeptide Y and Peptide YY in patients affected by Anorexia Nervosa and severe Obesity

Maria Chiara Masoni1 , Claudia D'Alessandro1, Claudio Scarpellini1, Lorenzo Ghiadoni1, Stefano Taddei11University of Pisa, Italy

Neuroendocrinology, Pituitary and Behaviour

P601

From the horse’s mouth: recommendations to improve care for pituitary patients. Results from a survey on pituitary patients’ satisfaction with information and support from healthcare professionals

Sue Jackson1 , Marianne Morris1, Jane Murray1, Tony Woods21University of the West of England, United Kingdom, 2Pituitary Foundation, United Kingdom

Neuroendocrinology, Pituitary and Behaviour

P602

Pituitary insufficiency with a HESX1 mutation: a new case

Pierre Lecomte1,2 , Alexandranu Saveanu3, Anne Barlier-Setti3, Thierry Brue3, Claire Lecomte1,2, Gaelle Barrande4, Christine Chabrolle1,2, Peggy Pierre1,21CHRU Bretonneau, France, 2UFR F. Rabelais, France, 3Lab. Molecular Biology, France, 4CHR, France

Neuroendocrinology, Pituitary and Behaviour

P603

PREVALENCE OF COLONIC POLYPS IN ACROMEGALIC PATIENTS AND RELATIONSHIP BETWEEN GLYCEMIC STATUS

YASEMIN TUTUNCU1 , YUSUF AYDIN1, DILEK BERKER1, SERHAT ISIK1, GULHAN AKCIL1, OSMAN YUKSEL2, TUNCAY DELIBASI1, SERDAR GULER11S.B. ANKARA NUMUNE RESEARCH AND TRAINING HOSPITAL, ENDOCRINOLOGY AND METABOLISM CLINIC, Turkey, 2S.B. ANKARA NUMUNE RESEARCH AND TRAINING HOSPITAL, GASTROENTEROLOGY CLINIC, Turkey

Neuroendocrinology, Pituitary and Behaviour

P604

Results of Acromegaly Patients Treated with Surgery and/or Somatostatin Analog and/or Radiotherapy in a University Hospital in Turkey

Özgür Demir1 , Vedia Tonyukuk Gedik1, Rifat Emral1, Murat Faik Erdogan1, Sevim Güllü1, Demet Çorapçioglu1, Ali Riza Uysal1, Nilgün Baskal1, Nuri Kamel11Ankara University, Turkey

Neuroendocrinology, Pituitary and Behaviour

P605

Hypothalamic-pituitary-adrenal axis in chronic fatigue syndrome

Djordje Marina1 , Svetlana Jelic1, Nada Kostic1, Zorica Caparevic1, Bozo Trbojevic2, Biljana Beleslin2, Sanja Ilic1, Milos Zarkovic21Clinical Center Dr Dragisa Misovic-Dedinje, Serbia, 2Institute of endocrinology, diabetes and metabolic disorders, Serbia

Neuroendocrinology, Pituitary and Behaviour

P606

Normalization of ACTH and cortisol responses to ghrelin in patients cured from Cushing’s disease (CD)

Dragana Miljic1 , Mirjana Doknic1, Sandra Pekic1, Marko Stojanovic1, Marina Djurovic1, Vera Popovic11Institute of Endocrinology, Clinical Center of Serbia, Serbia

Neuroendocrinology, Pituitary and Behaviour

P607

The role of androgen receptors in the medial amygdala on biosynthesis and stress-induced cellular activation of the paraventricular nucleus of the hypothalamus.

Brenda Bingham1 , Megan Gray1, Victor Viau11University of British Columbia, Canada

Neuroendocrinology, Pituitary and Behaviour

P608

GH RESISTANCE IN A GROUP OF CHRONIC FATIGUE SYNDROME PATIENTS

Francis Coucke1 , Yanina Dockx11Metares, Belgium

Neuroendocrinology, Pituitary and Behaviour

P609

Presenting Pattern and Etiologies of Hyperprolactinemia in North West of IRAN

Akbar Aliasgarzadeh11Tabriz University (Medical Sciences), Iran, Islamic Republic of

Neuroendocrinology, Pituitary and Behaviour

P610

AN EXCEPTIONAL IMAGE: MULTIPLE SCLEROSIS AND HYPOGONADISM

Ruth Boente1 , Eloísa Santos1, Jaime Lorenzo1, Manuel Antonio Sas11POVISA hospital, Spain

Neuroendocrinology, Pituitary and Behaviour

P611

Health Related Quality of Life in Patients with Diabetes Mellitus Type 2 in Comparison to Patients with Other Endocrine Diseases

Lina Lasaite1 , Gintautas Kazanavicius1, Edita Stankute1, Egidija Zasytyte11Institute of Endocrinology of Kaunas University of Medicine, Lithuania

Neuroendocrinology, Pituitary and Behaviour

P612

A DEVELOPED PREGNANCY IN A PATIENT WITH ACROMEGALY UNDER OCTREOTIDE LAR® TREATMENT

Fatih Kilicli1 , Serdal Korkmaz1, Sebila Dokmetas1, Fettah Acibucu11Cumhuriyet University, Faculty of Medicine, Department of Endocrinology, Turkey, 2Cumhuriyet University, Faculty of Medicine, Department of Internal Medicine, Turkey, 3Cumhuriyet University, Faculty of Medicine, Department of Endocrinology, Turkey, 4Cumhuriyet University, Faculty of Medicine, Department of Internal Medicine, Turkey

Neuroendocrinology, Pituitary and Behaviour

P613

Observational Outcome of Korean Acromegalics Based on OASIS Registry.

Sung-Woon Kim11Kyung Hee University School of Medicine, Korea, Republic of

Neuroendocrinology, Pituitary and Behaviour

P614

Plasma Thrombin-Activatable Fibrinolysis İnhibitor (TAFI) Antigen Levels in Acromegalic Patients

Mustafa Ozbek1 , Mehmet Erdogan2, Ozcan Ceneli3, Hakan Saltas4, Erdem Akbal5, Mustafa Kizilgun6, Kemal Ureten51Ministry of Health, Diskapi Y.B. Education and Research Hospital, Endocrinology and Metabolism Disease, Turkey, 2Ege University Medical School, Department of Endocrinology and Metabolism Disease, Turkey, 3Kirikkale University School of Medicine, Department of Hematology, Turkey, 4Ministry of Health, Diskapi Y.B. Education and Research Hospital, Microbiology department, Turkey, 5Ministry of Health, Diskapi Y.B. Education and Research Hospital, 1th Department of Internal Medicine, Turkey, 6Ministry of Health, Diskapi Pediatric Education and Research Hospital, Biochemistry, Ankara, Turkey

Neuroendocrinology, Pituitary and Behaviour

P615

PROLACTINOMA IN EAST-BLACK SEA TURKEY: A DESCRIPTION OF 51 CASES

OZGE UCUNCU1 , IRFAN NUHOGLU1, MUSTAFA KOCAK1, CIHANGIR EREM1, KUBRA AYDIN BAHAT1, H. ONDER ERSOZ11Karadeniz Technical University Medical Faculty Endocrinology and metabolism Department, Turkey

Neuroendocrinology, Pituitary and Behaviour

P616

ACROMEGALY İN THE EASTERN BLACK SEA REGİON OF TURKEY: A DESCRİPTİON OF 42 CASES

irfan nuhoglu1 , mustafa koçak1, özge üçüncü1, cihangir erem1, fatma saglam1, önder ersöz11BLACKSEA TECNICHAL UNIVERSITY MEDICAL FACULTY, Turkey

Neuroendocrinology, Pituitary and Behaviour

P617

LONG -TERM TREATMENT OF A MİSDİAGNOSED TSH-OMA PATİENT WİTH ANTİDEPRESSANTS AND ANTİTHYROİD DRUGS

irfan nuhoglu1 , özge üçüncü1, mustafa koçak1, cihangir erem1, adem demirel1, önder ersöz11BLACKSEA UNIVERSTY MEDICAL FACULTY, Turkey

Reproduction

P618

THE EFFECT OF NUTRITIONAL SUPPLEMENT (MENOPACE®) ON THE FREQUENCY OF HOT FLUSHES, NIGHT SWEATS, MOOD AND QUALITY OF LIFE IN POST-MENOPAUSAL WOMEN: A PLACEBO-CONTROLLED DOUBLE BLIND STUDY

Maria Andrikoula1 , Dawn Baker1, Jelena Nesic1, Lih Mei Liao1, Theodora Duka1, Gordana Prelevic11Royal Free Hospital, United Kingdom

Reproduction

P619

CLINICAL CARACTERISTICS OF ALGERIAN PCOS WOMEN

OULD-KABLIA SAMIA1 , ARIBI YAMINA1, KEMALI ZAHRA1, SEMROUNI MOURAD21CENTRAL HOSPITAL OF THE ARMY, Algeria, 2CPMC, Algeria

Reproduction

P620

Influence of hyperprolactinemia on prolactin receptor manifestation and hepatic bilirubin excretory activity under condition of female rat obstructive cholestasis

Natalia Kushnareva1 , Maria Sergeeva1, Olga Smirnova11M.V. Lomonosov Moscow State University, Russian Federation

Reproduction

P621

THE PREVALENCE OF SUBCLINICAL LATE – ONSET HYPOGONADISM IN MEN WITH DIABETES TYPE 2

Olga Vasilkova1,3 , Tatyana Mokhort2, Tamara Sharshakova1, Igor Sanec31Gomel State Medical University, Belarus, 2Belorussian State Medical University, Belarus, 3Gomel State Medical University, Belarus, 4The Republican Research Centre for Radiation Medicine and Human Ecology, Belarus

Reproduction

P622

Adiponectin increases insulin-like growth factor I-induced progesterone and estradiol secretion in human granulosa cells

Christine Chabrolle1,2 , Lucie Tosca2, Christelle Ramé2, Pierre Lecomte1, Dominique Royère1,2, Joelle Dupont21CHRU Bretonneau Département d'Endocrinologie et de Diabétologie, France, 2Unité de Physiologie de la Reproduction et des Comportements, Institut National de la Recherche Agronomique, France

Reproduction

P623

Effects of thyroid hormones on ovary granulosa cells: regulation of proliferation, survival and function

Silvia Misiti1,2 , Cecilia Verga Falzacappa2,3, Claudia Mangialardo1,2, Barbara Bucci2, Salvatore Raffa1, Giuliana Silvestrini1, Antonio Stigliano1,2, Vincenzo Toscano1,31Sapienza University II Faculty of Medicine, Italy, 2S.Peter Hospital Centro Ricerca, Italy, 3D.E.M., Italy, 4Sapienza University I Faculty of Medicine, Italy

Reproduction

P624

Successive degradation of StAR by soluble and membrane-bound mitochondrial proteases: plausible mechanism protecting steroidogenic mitochondria under “protein Stress”

Assaf Bahat1 , Joseph Orly11Dept. Biological Chemistry, Inst. of Life Sciences, The Hebrew University of Jerusalem, Israel

Reproduction

P625

AdipoR1 and AdipoR2 Inactivation by RNA interference in the KGN human granulosa cell line: Potential involvement of AdipoR1 in cell survival and AdipoR2 in steroidogenesis

PIERRE Peggy1,2 , FROMENT Pascal3, NEGRE Didier4, RAME Christelle2, CHABROLLE Christine1,2, LECOMTE Pierre1, DUPONT Joelle21Unité d’endocrinologie, diabétologie, maladies métaboliques,CHRU Bretonneau, France, 2Unité de Physiologie de la Reproduction et des Comportements, Institut National de la Recherche Agronomique, France, 3Unité de recherches Avicoles, Institut National de la Recherche Agronomique, France, 4Ecole Nationale Supérieure de Lyon, BioSciences Lyon-Gerland, France

Reproduction

P626

Progesterone suppression of the male hypothalamo-pituitary gonadal axis is partially reversed by the progesterone antagonist mifepristone

Joseph McIntosh1, Ros Walley1, Baerbel Wittke1, David Sudworth1, David Howe11Pfizer Ltd, United Kingdom

Reproduction

P627

Isradipine inihibits oxytocin-induced contractions of isolated myometrium from late pregnant rat

Mehmet Nalbant1 , Selim Kutlu2, Selahattin Kumru1, Mete Ozcan3, Ergul Alcin2, Bilgin Gurates1, Ahmet Ayar21Firat University, Faculty of Medicine, Obs and Gyn, Turkey, 2Firat University, Faculty of Medicine, department of Physiology, Turkey, 3Firat University, Faculty of Medicine, department of Biophysics, Turkey

Reproduction

P628

Hormonal regulation of in vivo transfection efficiency after gene transfer into the uterus and oviduct.

Pedro Esponda1 , Miguel Relloso11Centro de Investigaciones Biológicas. CSIC, Spain

Reproduction

P629

PROLONGED QT (corrected) DISPERSION IN WOMEN WITH POLYCYSTIC OVARY SYNDROME

Kerem Sezer1 , Ozlem Pata3, Ahmet Camsari21Department of Endocrinology and Metabolic Diseases, School of Medicine, Mersin University, Turkey, 2Department of Cardiology, School of Medicine, Mersin University, Turkey, 3Department of Gynecology and Obstetrics, Acibadem Hospital, Turkey

Reproduction

P630

FREE THIOLS IN HUMAN SPERMATOZOA: CORRELATION WITH Na+/K+-ATPase, Ca2+- ATPase ACTIVITIES AND SPERM MOTILITY

ARIANNA VIGNINI1, EDDI BULDREGHINI2, LAURA NANETTI1, FRANCESCA RAFFAELLI1, FRANCESCA PAGGI2, MARCO BOSCARO2, LAURA MAZZANTI1, GIANCARLO BALERCIA21Institute of Biochemistry, School of Medicine, Polytechnic University of Marche, Italy, 2Andrology Unit, Endocrinology Division, Dept of Internal Medicine and Applied Technologies, Umberto I Hospital, School of Medicine, Polytechnic University of Marche, Italy

Reproduction

P631

Influence of polycystic ovary syndrome and obesity on vascular parameters (common carotid artery intima-media thickness - CCA-IMT, common carotid artery compliance - CP-CCA and endothelium function of the brachial artery – FMD) related to the process of atherosclerosis.

Jose Marcondes1 , Cristiano Barcellos1, Sylvia Lage1,3, Angela Romano1,3, Michele Rocha1, Sylvia Hayashida1,2, Daniela Curi1,2, Edmund Baracat1,21Endocrine Unit - Hospital das Clinicas, Brazil, 2Gynecological Unit - Hospital das CLinicas, Brazil, 3Itensive Care Unit - Instituto do Coracao, Brazil

Reproduction

P632

IMPACT OF THE TYPE OF DIABETES IN PREGNANCY UPON PREGNANCY OUTCOME

Malak Elazrag1, Mohammed Sultan1,2, Hamida Shaliry11Diabetic pregnancy Ciinic, Libyan Arab Jamahiriya, 2Diabetic pregnancy Unit, Libyan Arab Jamahiriya, 3Diabetic pregnancy Unit, Libyan Arab Jamahiriya

Reproduction

P633

Advanced Glycosylated End products are associated with Anovulatory markers in women with Polycystic Ovary Syndrome

Evanthia Diamanti-Kandarakis, Athanasia Piouka2, Sarantis Livadas1, Christine Piperi3, Ilias Katsikis2, Athanasios Papavasiliou3, Dimitrios Panidis21University of Athens Medical School, First Department of Medicine, Endocrine section, Greece, 2Division of Endocrinology and Human Reproduction, Second Department of Obstetrics and Gynecology, Greece, 3University of Athens Medical School, Laboratory of Biological Chemistry, Greece

Reproduction

P634

A systematic review and a meta-analysis on adiponectin levels in women with Polycystic Ovary Syndrome.

Konstantinos Toulis1 , Dimitrios Goulis1, Dimitrios Farmakiotis1, Ilias Katsikis1, Neoklis Georgopoulos1, Basil Tarlatzis1, Ioannis Papadimas1, Dimitrios Panidis11Aristotle University, Greece, 2Medical School, Greece

Reproduction

P635

Gonadotropin releasing hormone-induced histone modifications and gonadotropin gene expression

Philippa Melamed1,2 , Andrea Wijeweera11Technion - Israel Institute of Technology, Israel, 2National University of Singapore, Singapore

Reproduction

P636

Candidate gene analyses in Caucasian patients with Primary Ovarian Insufficiency (POI).

RAFFAELLA ROSSETTI1,2 , CHIARA CACCIATORI1, ANNA MAROZZI3, DANIELA CORDELLA1, SILVIA BIONE4, SALVATORE CANNAVO'5, DAN BERNARD6, TREVOR COLE7, JILL CLAYTON-SMITH8, PAOLO BECK-PECCOZ1, LUCA PERSANI1,21Dept. of Medical Sciences, University of Milan; Lab of Experimental Endocrinology, Istituto Auxologico Italiano IRCCS and Endocrinology and Diabetology Unit, Fondazione Ospedale Policlinico IRCCS, Italy, 2Centro Interuniversitario per la Ricerca della basi molecolari delle Malattie della Riproduzione (CIRMAR), Italy, 3Dept. of Biology and Genetics for Medical Sciences, University of Milan, Italy, 4Institute of Molecular Genetics, CNR, Italy, 5Dept. of Endocrinology, Ospedale Policlinico Universitario, Italy, 6Department of Pharmacology and Therapeutics, McGill University, Canada, 7Clinical Genetics Unit, Birmingham Women’s Hospital, United Kingdom, 8Dept. of Medical Genetics, St. Mary’s Hospital, United Kingdom

Reproduction

P637

Penile size and testicular volume in healthy Lithuanian newborns

Romualdas Tomas Preiksa1 , Birute Zilaitiene1, Valentinas Matulevicius11Institute of Endocrinology, Kaunas University of Medicine, Lithuania

Reproduction

P638

THE EFFECTS OF STRESS ON THE HISTOLOGICAL STRUCTURE OF RAT TESTIS

TUBA DEMIRCI1 , ELVAN ÖZBEK11ATATÜRK UNIVERSITY MEDICAL SCHOOL DEPARTMENT OF HISTOLOGY AND EMBRYOLOGY, Turkey

Reproduction

P639

Effect of Lamotrigine and Carbamazepine on Selected Reproductive Hormones, Lipid Profiles and Ovarian Histology in Female Rats

Bassim Irheim Mohammad, Najah Al-Mousawi2, Azhar Al-Terahi2, Ekhas Hassan21College of Medicine, Diwaniyah University, Iraq, 2College of Medicine, Kufa University, Iraq

Reproduction

P640

Effects of electromagnetic fields of cellular phone on testosterone and progesterone hormones rate in Syrian Hamsters (Mesocricetus auratus)

alireza lotfi1 , habib aghdam shahryar11department of animal science, Islamic Azad University, shabestar branch, Iran, Islamic Republic of

Reproduction

P641

Is there a need for withdrawal test with oral micronized natural progesterone in the evaluation of women with polycystic ovary syndrome?

Sarantis Livadas1 , Georgios Boutzios1, Frangiskos Economou1, Krystallenia Alexandraki1, Xenofon Xyrafis1, Aristea Zerva1, Athanasios Karachalios1, Evanthia Diamanti- Kandarakis11University of Athens Medical School, First Department of Medicine, Endocrine section, Greece

Reproduction

P642

Gonadal Function in Male Mountain Bikers

Faruk Yamaner1, Hulusi Atmaca1, Taner Bayraktaroglu1, Mustafa Aydin1, Selim Aydemir11Medical High School, Hitit University, Turkey, 2Medical Faculty, Endocrinology and Metabolism, Zonguldak Karaelmas University, Turkey, 3Medical Faculty, Endocrinology and Metabolism, Zonguldak Karaelmas University, Turkey, 4Medical Faculty, Cardiology, Zonguldak Karaelmas University, Turkey, 5Medical Faculty, Gastroenterology, Zonguldak Karaelmas University, Turkey

Reproduction

P643

THE EFFECTS OF METFORMIN THERAPY IN WOMEN WITH IDIOPATHIC HIRSUTISM

Kursad Unluhizarci1 , Nuran Ahu Baysal1, Zuleyha Karaca1, Fatih Tanriverdi1, Fahrettin Kelestimur11Department of Endocrinology Erciyes University Medical School, Turkey

Reproduction

P644

IMPACT OF GESTATIONAL IMPAIRED GLUCOSE TOLERANCE TEST (GIGTT) ON PREGNANCY OUTCOME

Mohamed Sultan1 , Malak Elazrag1, Huda Khiaif11Diabetic unit Aljalaa Maternity Hospital, Libyan Arab Jamahiriya, 2Diabetic pregnacy clinic Tripoli Medical Centerc, Libyan Arab Jamahiriya, 3Diabetic unit Aljalaa Maternity Hospital, Libyan Arab Jamahiriya

Reproduction

P645

A monocentric study of 360 consecutive patients presenting with Premature Ovarian Failure

Anne Bachelot1 , Agnès Rouxel1, Nathalie Massin1, Jérome Dulon1, Carine Courtillot1, Frédérique Kuttenn1, Philippe Touraine11Endocrinology and Reproductive Medicine, Hôpital Pitié-Salpétrière, France

Reproduction

P646

Effect of an Oral Contraceptive on Emotional Distress of Women with Polycystic Ovary Syndrome: A Prospective Study

Nese Cinar1 , Ayla Harmanci1, Basaran Demir2, Bülent O. Yildiz11Hacettepe University School of Medicine, Department of Internal Medicine, Endocrinology and Metabolism Unit, Turkey, 2Hacettepe University School of Medicine, Department of Psychiatry, Turkey

Reproduction

P647

Spermatogenesis in men with Late-Onset Hypogonadism (LOH), receiving testosterone- gel.

George Mskhalaya1 , Yulia Tishova3, Vadim Vadov1, Dariya Gusakova2, Svetlana Kalinchenko11Peoples' Friendship University of Russia, Russian Federation, 2Scientific and Research Institute of Urology, Russian Federation, 3Research Center for Endocrinology, Russian Federation

Reproduction

P648

Prostatic secreted proteins in mice and rats: Identification using mass spectrometric analysis and the hormone dependent expression

Nariaki Fujimoto1 , Tomoharu Suzuki1, Shigeru Ohta11Hiroshima University, Japan

Reproduction

P649

Erectile Dysfunction (ED) among HIV-infected Men is Associated with Protease Inhibitor (PI) Containing HAART.

Oscar Moreno-Perez1, Corina Escoin2, Carmen Serna- Candel4, Nieves Arias1, Rocio Alfayate3, Vicente Boix2, Esperanza Merino2, Joaquin Portilla2, Antonio Pico11Department Endocrinology, Hospital General Universitario Alicante, Spain, 2Unit of Infectious Diseases, Hospital General Universitario Alicante, Spain, 3Hormones Laboratory, Hospital General Universitario Alicante, Spain, 4Department Neurology, Hospital Clinico San Carlos, Spain

Reproduction

P650

Insulin like growth factor binding protein-1 in PCOS: a systematic review and meta-analysis.

Claire Kelly1 , Sophie Stenton1, Hany Lashen11University of Sheffield, United Kingdom

Reproduction

P651

SCREENING OF MATERNAL THYREOPATHIES IN SLOVAKIA – DOES IT WORTH FOR IT?

Helena Urbankova 1, Jan Hruska2, Peter Vanuga11Department of Endocrinology, National Institute of Endocrinology and Diabetology, Slovakia, 2Gynecology Outpatient Service, Slovakia

Reproduction

P652

Temporal Dexamethasone Treatment: Responses in Uterine Proliferative Mechanisms Induced by Neurogenic Stimulation.

Fitzgerald Spencer1 , Limen Qi21Southern University, United States, 2University of Illinois, United States

Reproduction

P653

HYPERPROLACTINEMIA IN POLYCYSTIC OVARY SYNDROME

Kemal Agbaht1 , Halis Yerlikaya1, Ozgur Demir1, Sevim Gullu11Ankara University, Faculty of Medicine, Endocrinology and Metabolic Diseases, Turkey

Reproduction

P654

SERUM ANDROGEN LEVELS CORRELATE WELL WITH METABOLIC PARAMETERS IN POLYCYSTIC OVARY SYNDROME

Kemal Agbaht1 , Halis Yerlikaya1, Sevim Gullu11Ankara University, Faculty of Medicine, Endocrinology and Metabolic Diseases, Turkey

Reproduction

P655

EFFECTS OF SURGICAL STRESS, LIGHTING STRESS AND LACK OF LIGHT ON LEPTIN PLASMATIC LEVELS adernal 'endocrine disrupts'' neuroendocrinology'pituitary and behaiviour

Mrcio Vilela1 , João Lúcio dos Santos Júniora1, Mamman Ziyona11aDepartment of Gynecology and Obstetrics, Brazil

Reproduction

P656

Use of Estradiol Benzoate in presynch method in lactating dairy cows

Vahid Ghaffari Laleh1 , Ali Asadi1, Mohammad Tagi Mohammadi11Young Researchers club of Tabriz, Iran, Islamic Republic of

Reproduction

P657

Prolonged treatment with N-acetylcysteine and L-arginine restores gonadal function in patients with PCO s